Systems and methods are provided for automated identification of vascular pathology in computed tomography images. A region of interest in a chest of a patient is imaged via a computed tomography scanner to provide an image. The region of interest includes at least one of the ascending aorta, the central pulmonary artery, the left and right pulmonary arteries, the lobar arteries extending from the left and right pulmonary arteries, the aortic arch, and the descending aorta of the patient. For each of a plurality of locations within the region of interest, a value representing a variation in radiodensity values for voxels within the location is determined from the image to provide a set of variation values. At a derived model, a parameter representing vascular pathology within the patient is determined from the set of variation values and provided to a user at an associated output device.

Methods, systems, and devices for accessing tissue outside a bronchus and marking the location of a biopsy are provided. The method includes loading a navigation plan into a navigation system with the navigation plan including a CT volume generated from a plurality of CT images, inserting an extended working channel (EWC) including a location sensor into a patient's airways, registering a sensed location of the EWC with the CT volume of the navigation plan, and selecting a target in the navigation plan located outside the periphery of a patient's airways. The method further includes navigating the EWC and location sensor proximate the target, inserting a piercing catheter into the EWC, piercing through an airway wall to reach the target, storing a position of the location sensor in the navigation system as a biopsy location, and performing a biopsy at the stored biopsy location.

Methods, systems, and devices for accessing tissue outside a bronchus and marking the location of a biopsy are provided. The method includes loading a navigation plan into a navigation system with the navigation plan including a CT volume generated from a plurality of CT images, inserting an extended working channel (EWC) including a location sensor into a patient's airways, registering a sensed location of the EWC with the CT volume of the navigation plan, and selecting a target in the navigation plan located outside the periphery of a patient's airways. The method further includes navigating the EWC and location sensor proximate the target, inserting a piercing catheter into the EWC, piercing through an airway wall to reach the target, storing a position of the location sensor in the navigation system as a biopsy location, and performing a biopsy at the stored biopsy location.

Imaging systems and methods for imaging assisted interventional procedure that receive images of a region of interest, that automatically detect in the images a contrast agent puff as it courses through the region of interest, and that generate a display including a video replay loop of contrast enhanced images based on the automatic detection of the contrast agent puff.

Imaging systems and methods for imaging assisted interventional procedure that receive images of a region of interest, that automatically detect in the images a contrast agent puff as it courses through the region of interest, and that generate a display including a video replay loop of contrast enhanced images based on the automatic detection of the contrast agent puff.

A system for constructing fluoroscopic-based three-dimensional volumetric data of a target area within a patient from two-dimensional fluoroscopic images including a structure of markers, a fluoroscopic imaging device configured to acquire a sequence of images of the target area and of the structure of markers, and a computing device. The computing device is configured to estimate a pose of the fluoroscopic imaging device for at least a plurality of images of the sequence of images based on detection of a possible and most probable projection of the structure of markers as a whole on each image of the plurality of images. The computing device is further configured to construct fluoroscopic-based three-dimensional volumetric data of the target area based on the estimated poses of the fluoroscopic imaging device.

A system for constructing fluoroscopic-based three-dimensional volumetric data of a target area within a patient from two-dimensional fluoroscopic images including a structure of markers, a fluoroscopic imaging device configured to acquire a sequence of images of the target area and of the structure of markers, and a computing device. The computing device is configured to estimate a pose of the fluoroscopic imaging device for at least a plurality of images of the sequence of images based on detection of a possible and most probable projection of the structure of markers as a whole on each image of the plurality of images. The computing device is further configured to construct fluoroscopic-based three-dimensional volumetric data of the target area based on the estimated poses of the fluoroscopic imaging device.

An X-ray imaging apparatus is provided with an X-ray irradiation unit, a detector, an image generation unit, an optical imaging unit for capturing an optical image, a storage unit for storing a trained model, the trained model being configured to output determination information to an input image based on the optical image, the determination information determining a state regarding an imaging range of a predetermined site of the subject or a relative position of the predetermined site to the other site of the subject, a control unit for acquiring the determination information, using the trained model, and a notification unit.

An X-ray imaging apparatus is provided with an X-ray irradiation unit, a detector, an image generation unit, an optical imaging unit for capturing an optical image, a storage unit for storing a trained model, the trained model being configured to output determination information to an input image based on the optical image, the determination information determining a state regarding an imaging range of a predetermined site of the subject or a relative position of the predetermined site to the other site of the subject, a control unit for acquiring the determination information, using the trained model, and a notification unit.

A surgical instrument assembly may include a processor, a surgical instrument configured to operate on an anatomical structure, and a display coupled to the processor and attached to the surgical instrument. The processor can be configured to determine a position of the medical imaging device, from which the medical imaging device can generate an X-ray image that includes holes of an intramedullary nail shown as circles, for instance perfect circles. In an example, the processor identifies the intramedullary nail, so as to determine an intramedullary nail identity, and determines the position of the medical imaging device based on a portion of at least two locking holes of the intramedullary nail and based on the intramedullary nail identity.