Aspects described herein relate to estimating mean arterial pressure (MAP) of a living being. The estimating may include obtaining pulsatile arterial blood pressure (pABP) waveform, obtaining arterial blood flow (ABF) waveform, identifying a set of segments of the pABP waveform in steady state, identifying a set of segments of the ABF waveform in steady state, and estimating the MAP based on the identified segment of the pABP waveform in steady state and the identified segment of the ABF waveform in steady state

Aspects described herein relate to estimating mean arterial pressure (MAP) of a living being. The estimating may include obtaining pulsatile arterial blood pressure (pABP) waveform, obtaining arterial blood flow (ABF) waveform, identifying a set of segments of the pABP waveform in steady state, identifying a set of segments of the ABF waveform in steady state, and estimating the MAP based on the identified segment of the pABP waveform in steady state and the identified segment of the ABF waveform in steady state

Multi-mode capacitive micromachined ultrasound transducer (CMUT) and associated devices systems, and methods are provided. In an embodiment, an intravascular device includes a flexible elongate member having a proximal portion, a distal portion, and a first sensor assembly disposed at the distal portion of the flexible elongate member. The first sensor assembly comprising comprises a first array of capacitive micromachined ultrasonic transducers (CMUTs). The first sensor assembly comprises at least two of a pressure sensor, a flow sensor, or an imaging sensor. In some embodiments, the intravascular device further includes a second sensor assembly comprising a second array of CMUTs.

Multi-mode capacitive micromachined ultrasound transducer (CMUT) and associated devices systems, and methods are provided. In an embodiment, an intravascular device includes a flexible elongate member having a proximal portion, a distal portion, and a first sensor assembly disposed at the distal portion of the flexible elongate member. The first sensor assembly comprising comprises a first array of capacitive micromachined ultrasonic transducers (CMUTs). The first sensor assembly comprises at least two of a pressure sensor, a flow sensor, or an imaging sensor. In some embodiments, the intravascular device further includes a second sensor assembly comprising a second array of CMUTs.

A system and method for noninvasively measuring blood pressure is disclosed. In one embodiment, the system includes a monitoring cuff comprising at least one sensor implanted within the monitoring cuff, the at least one sensor being configured to detect blood flow data in a user, an occlusion cuff configured to inflate and deflate to restrict and permit blood flow in the user, the occlusion cuff being in electrical communication with the monitoring cuff, and a computing device configured to control the inflation, deflation, and pressure applied by the occlusion cuff, and the computing device being configured to record and analyze the blood flow data detected by the monitoring cuff.

An implantable sensor system using one or more sensor implants comprised of micro-electrical mechanical system (MEMS) sensors for the accurate and continuous measurement of physiological hemodynamic signals such as diastolic and systolic blood pressure. Sensor implants are configured to be subcutaneously injected to a placement site adjacent a blood vessel. In some embodiments, sensors comprise micromachined ultrasonic transducers.

An implantable sensor system using one or more sensor implants comprised of micro-electrical mechanical system (MEMS) sensors for the accurate and continuous measurement of physiological hemodynamic signals such as diastolic and systolic blood pressure. Sensor implants are configured to be subcutaneously injected to a placement site adjacent a blood vessel. In some embodiments, sensors comprise micromachined ultrasonic transducers.

The present invention comprises a novel method to utilize the diameter of the internal jugular vein, obtained using an ultrasound machine, to estimate a patient's volume status and cardiac ventricular function. In this technique, the ultrasound machine is used to measure the diameter of the internal jugular vein (IJV) lumen. In addition, the ultrasound machine is used to measure the respiratory variation in the IJV lumen diameter, measured as the difference between the maximum and minimum diameter divided by the maximum diameter and expressed as a percentage. The ultrasound machine is also used to identify a complete approximation of the IJV diameter into 0 millimeters with deep breathing and/or sniff. The above information is used to estimate the patient's volume and cardiac function status.

The present invention comprises a novel method to utilize the diameter of the internal jugular vein, obtained using an ultrasound machine, to estimate a patient's volume status and cardiac ventricular function. In this technique, the ultrasound machine is used to measure the diameter of the internal jugular vein (IJV) lumen. In addition, the ultrasound machine is used to measure the respiratory variation in the IJV lumen diameter, measured as the difference between the maximum and minimum diameter divided by the maximum diameter and expressed as a percentage. The ultrasound machine is also used to identify a complete approximation of the IJV diameter into 0 millimeters with deep breathing and/or sniff. The above information is used to estimate the patient's volume and cardiac function status.

A method includes obtaining a baseline blood pressure at an initial time window; estimating a plurality of intermediate blood pressure change estimates, the intermediate blood pressure change estimates correspond to respective time windows that are subsequent to the initial time window; estimating a final blood pressure change estimate between the initial and final time windows; and obtaining the blood pressure by adding the baseline blood pressure to the final blood pressure change estimate. Estimating the final blood pressure includes estimating a first blood pressure change between the initial time window and the final time window; estimating a plurality of second blood pressure changes, each second blood pressure change is between a respective time window of the respective time windows and the final time window; and estimating the final blood pressure change estimate as a combination of the first blood pressure change and the plurality of second blood pressure changes.