The disclosure provides wearable cardiac arrest detection and alerting device that incorporates a non-invasive sensor based on optical and/or electrical signals transmitted into and received from human tissue containing blood vessels, and that transcutaneously quantifies the wearer's heart rate. The heart-rate quantification enables the detection of the absence of any heart beat by the wearable detection and alerting device indicative of the occurrence of a cardiac arrest, wherein the heart is no longer achieving effective blood circulation in the individual wearing the device. The display on the wearable cardiac arrest detection and alerting device may include the elapsed time since the time of detection of a heart rate that is below a predetermine lower limit value, i.e., the detected occurrence of a cardiac arrest event.

The present invention relates to the field of ultrasounds and imagining of the coronary blood flow of the heart. Patients with coronary microvascular dysfunction (CMD) have poor prognostic with significantly higher rates of cardiovascular events, including hospitalization for heart failure, sudden cardiac death, and myocardial infarction (MI). Despite the urgent clinical need, there are no non-ionizing and non-invasive techniques available in clinic to directly visualize the coronary microvasculature and assess the local coronary microvascular system. Flow imaging remains a difficult task to perform in the heart because of the fast movements of this organ. In order to overcome the limitations of actual imaging methods for the coronary blood flow, the inventors proposed an ultrasound ultrafast imaging method that automatically detect the time periods in which the myocardium velocity is low and estimate the coronary flow velocity and the tissue velocity from the same data acquisition.

The present invention relates to the field of ultrasounds and imagining of the coronary blood flow of the heart. Patients with coronary microvascular dysfunction (CMD) have poor prognostic with significantly higher rates of cardiovascular events, including hospitalization for heart failure, sudden cardiac death, and myocardial infarction (MI). Despite the urgent clinical need, there are no non-ionizing and non-invasive techniques available in clinic to directly visualize the coronary microvasculature and assess the local coronary microvascular system. Flow imaging remains a difficult task to perform in the heart because of the fast movements of this organ. In order to overcome the limitations of actual imaging methods for the coronary blood flow, the inventors proposed an ultrasound ultrafast imaging method that automatically detect the time periods in which the myocardium velocity is low and estimate the coronary flow velocity and the tissue velocity from the same data acquisition.

An ultrasound system includes a transducer array configured to generate analog ultrasound signals. The system includes one or more analog-to-digital converters (ADCs) in communication with the transducer array. The ADCs is configured to convert the analog ultrasound signals to digital ultrasound signals. The system includes a processor circuit in communication with the ADCs. The processor circuit includes digital in-phase/quadrature (I/Q) mixers configured to generate digital continuous wave (CW) Doppler signals based on the digital ultrasound signals. The processor circuit is configured to process the digital CW Doppler signals, generate a graphical representation of a distribution of blood flow velocities over a plurality of cardiac cycles, and output the graphical representation to a display in communication with the processor circuit.

An ultrasound system includes a transducer array configured to generate analog ultrasound signals. The system includes one or more analog-to-digital converters (ADCs) in communication with the transducer array. The ADCs is configured to convert the analog ultrasound signals to digital ultrasound signals. The system includes a processor circuit in communication with the ADCs. The processor circuit includes digital in-phase/quadrature (I/Q) mixers configured to generate digital continuous wave (CW) Doppler signals based on the digital ultrasound signals. The processor circuit is configured to process the digital CW Doppler signals, generate a graphical representation of a distribution of blood flow velocities over a plurality of cardiac cycles, and output the graphical representation to a display in communication with the processor circuit.

A probe is configured with a flushing port and an evacuation port to establish a flow path to remove blood from a resected tissue. The probe comprises a balloon configured to expand and contact the resected tissue to compress filaments and improve access to the underlying blood vessels for coagulation with an energy source. An endoscope can be used to view the tissue, and the balloon may comprise a transparent material or a viewing port to allow imaging of the bleeding tissue through the balloon. The probe may have a light source to illuminate the tissue with a beam oriented at an oblique angle to the tissue surface, which can decrease interference from blood and may allow more localized coagulation of the blood vessel.

The disclosure relates to a method for improving pacing settings of a pace maker, comprising: receiving a set of pacing settings for the pace maker; receiving measurements or fluid mechanics data relating to the heart of a subject for all or part of the pacing settings of the set; estimating hemodynamic forces parameters by elaborating such measurements or inputting hemodynamic forces parameters as received; estimating hemodynamic forces parameters in the heart of the subject by elaborating such hemodynamic forces; selecting an optimal pacing setting of the set, or calculating further pace settings, based on the hemodynamic forces parameters as estimated A corresponding device and computer program are also disclosed.

A medical image processing device of an embodiment includes processing circuitry. The processing circuitry is configured to acquire a contrast-enhanced image of a subject at least after a portal vein dominant phase among contrast-enhanced images of the subject to which a contrast medium has been administered in a process of reaching a post-vascular phase from an artery dominant phase via the portal vein dominant phase, and detect a site where the contrast medium has been washed out as a defective part in the contrast-enhanced image after the portal vein dominant phase.

A medical image processing device of an embodiment includes processing circuitry. The processing circuitry is configured to acquire a contrast-enhanced image of a subject at least after a portal vein dominant phase among contrast-enhanced images of the subject to which a contrast medium has been administered in a process of reaching a post-vascular phase from an artery dominant phase via the portal vein dominant phase, and detect a site where the contrast medium has been washed out as a defective part in the contrast-enhanced image after the portal vein dominant phase.

An ultrasound diagnosis apparatus including: an ultrasound probe having a transducer array; and a processor configured to: perform transmission and reception of an ultrasonic beam from the transducer array toward a subject, into which contrast media including microbubbles is introduced; image a reception signal output from the transducer array to generate an ultrasound image of the subject; acquire trajectories of the microbubbles in a one cross section of the subject by tracking movement of the microbubbles based on the ultrasound image corresponding to the one cross section of the subject; detect, as a feature point, a trajectory, in which a distance between a start point and an end point in a prescribed time range is less than a prescribed value, among the trajectories of the microbubbles; and display the ultrasound image, the acquired trajectories and the detected feature point on the display unit.