An ultrasound signal processor uses an excitation generator to cause displacement of a membrane or surface while a series of ultrasound pulses are applied to the membrane or surface. Phase differences between a transmitted signal and received signal are examined to determine the movement of the membrane or surface in response to the applied excitation. An examination of the phase response of the membrane or surface provides a determination as to whether the fluid type behind the membrane or surface is one of: no fluid, serum fluid, or purulent fluid.

Certain aspects presented herein provide systems and methods utilizing one or more machine learning models in determining a severity of vitreous disease, and in particular, vitreous opacities. Such machine learning models are trained based on historical patient data to determine the severity of vitreous opacities afflicting a current patient. The severity determination may thereafter be utilized to inform treatment decisions for the current patient, including patient suitability for certain types of treatment.

The present disclosure is directed to improvement of a precision ultrasound scanner for imaging the human eye and in particular to method for the manufacture and assembly of an eye piece suitable for use with an ultrasonic arc scanning device. The method disclosed herein describes an improved eye piece for ultrasound imaging that reduces saline leakage around its optically and acoustically transparent membrane and improves the efficiency of assembly.

The present disclosure is directed to improvement of a precision ultrasound scanner for imaging the human eye and in particular to method for the manufacture and assembly of an eye piece suitable for use with an ultrasonic arc scanning device. The method disclosed herein describes an improved eye piece for ultrasound imaging that reduces saline leakage around its optically and acoustically transparent membrane and improves the efficiency of assembly.

Systems and methods are provided for in vivo pre-surgical characterization of lenses, such as cataractous lenses. A method comprises obtaining an electromagnetically-measured value related to the axial thickness of the lens, obtaining an ultrasound-measured value related to the axial thickness of the lens, calculating a relationship value based upon the electromagnetically-measured value and the ultrasound-measured value, and determining a mechanical property value based upon the calculated relationship value. The mechanical property may relate to lens hardness, rigidity, or density, or the amount of energy for a phacoemulsification procedure. A system may comprise an optical interferometer for measuring data to obtain the electromagnetically-measured value and an ultrasound biometer for measuring data to obtain the ultrasound-measured value.

Systems and methods are provided for in vivo pre-surgical characterization of lenses, such as cataractous lenses. A method comprises obtaining an electromagnetically-measured value related to the axial thickness of the lens, obtaining an ultrasound-measured value related to the axial thickness of the lens, calculating a relationship value based upon the electromagnetically-measured value and the ultrasound-measured value, and determining a mechanical property value based upon the calculated relationship value. The mechanical property may relate to lens hardness, rigidity, or density, or the amount of energy for a phacoemulsification procedure. A system may comprise an optical interferometer for measuring data to obtain the electromagnetically-measured value and an ultrasound biometer for measuring data to obtain the ultrasound-measured value.

One embodiment is directed to a system comprising a head-mounted member removably coupleable to the user's head; one or more electromagnetic radiation emitters coupled to the head-mounted member and configured to emit light with at least two different wavelengths toward at least one of the eyes of the user; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering at least one blood vessel of the eye; and a controller operatively coupled to the one or more electromagnetic radiation emitters and detectors and configured to cause the one or more electromagnetic radiation emitters to emit pulses of light while also causing the one or more electromagnetic radiation detectors to detect levels of light absorption related to the emitted pulses of light, and to produce an output that is proportional to an oxygen saturation level in the blood vessel.

One embodiment is directed to a system comprising a head-mounted member removably coupleable to the user's head; one or more electromagnetic radiation emitters coupled to the head-mounted member and configured to emit light with at least two different wavelengths toward at least one of the eyes of the user; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering at least one blood vessel of the eye; and a controller operatively coupled to the one or more electromagnetic radiation emitters and detectors and configured to cause the one or more electromagnetic radiation emitters to emit pulses of light while also causing the one or more electromagnetic radiation detectors to detect levels of light absorption related to the emitted pulses of light, and to produce an output that is proportional to an oxygen saturation level in the blood vessel.

The present disclosure relates to ultrasound imaging and treatment of an eye and in particular directed to an apparatus and method for reducing intraocular pressure by 1) ablating the ciliary process which is the structure responsible for production of aqueous humor and 2) by vibrating the trabecular mesh to stimulate better drainage of fluid through the trabecular mesh and out of the eye. The present disclosure describes an apparatus and method for forming a high precision image of the eye wherein the resolution is sufficient to image, for example, ciliary body and region around the trabecular mesh. The present disclosure further discloses an imaging transducer and an irradiating therapeutic transducer that can be mounted such that they are movable between a plurality of positions.

The present disclosure relates to ultrasound imaging and treatment of an eye and in particular directed to an apparatus and method for reducing intraocular pressure by 1) ablating the ciliary process which is the structure responsible for production of aqueous humor and 2) by vibrating the trabecular mesh to stimulate better drainage of fluid through the trabecular mesh and out of the eye. The present disclosure describes an apparatus and method for forming a high precision image of the eye wherein the resolution is sufficient to image, for example, ciliary body and region around the trabecular mesh. The present disclosure further discloses an imaging transducer and an irradiating therapeutic transducer that can be mounted such that they are movable between a plurality of positions.