The present invention provides compositions and methods for reducing inflammation in the lungs of a mammal that is afflicted by a condition that leads to inflammation in the lungs. The compositions and methods described herein include agents that inhibit inflammasome signaling in the mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s).

Systems and methods are provided for decentralized rail signaling and positive train control. A decentralized train control system may include a plurality of wayside units, configured for placement on or near tracks in a railway network, and one or more train-mounted units, each configured for use in a train operating in a railway network that support use of the decentralized train control system. Each train-mounted unit may configured to receive communicate with any wayside unit and/or train-mounted unit that comes within range, with the communicating including use of ultra-wideband (UWB) signals, and for generating control information based on the UWB signals, for use in controlling one or more functions associated with operation of the train.

Enhanced transit location systems and methods are provided. A method comprises receiving, into a vehicle radio located on a vehicle traveling along a roadway, signals transmitted by wayside radios located along the roadway; and determining a location of the vehicle along the roadway based on the received signals.

Enhanced transit location systems and methods are provided. A method comprises receiving, into a vehicle radio located on a vehicle traveling along a roadway, signals transmitted by wayside radios located along the roadway; and determining a location of the vehicle along the roadway based on the received signals.

A method for extracting and analyzing spatial information of a control and protection zone of rail transit with multiple threshold constraints, including the following steps: 1, performing format conversion on a data file and extracting a plurality of coordinate points; 2, selecting key points from the plurality of coordinate points for data simplification to obtain a simplified limit line, a simplified outer structure edge line and a simplified boundary line of construction; 3, programming the simplified limit line, the simplified outer structure edge line, and the simplified boundary line of construction, calling a database, and reading data therefrom for spatial relationship comparison; 4, determining whether the construction of a rail-involved construction project intrudes into a control and protection zone of rail transit according to a result of the spatial relationship comparison, thus completing the extraction and analysis of the spatial information of the control and protection zone of rail transit.

A control unit for controlling a rolling stock includes a user interface. The control unit is configured to receive, via the user interface, a plurality of user inputs corresponding to a plurality of users servicing the rolling stock, determine whether at least one user of the plurality of users remains servicing the rolling stock, and if at least one user of the one or more users remains servicing the rolling stock, prevent unauthorized movement of the rolling stock. Other example control units, computer systems including one or more control units, and computer-implemented methods for preventing unauthorized movement of a rolling stock are also disclosed.

A control unit for controlling a rolling stock includes a user interface. The control unit is configured to receive, via the user interface, a plurality of user inputs corresponding to a plurality of users servicing the rolling stock, determine whether at least one user of the plurality of users remains servicing the rolling stock, and if at least one user of the one or more users remains servicing the rolling stock, prevent unauthorized movement of the rolling stock. Other example control units, computer systems including one or more control units, and computer-implemented methods for preventing unauthorized movement of a rolling stock are also disclosed.

Systems and methods are provided for worker protection system with ultra-wideband (UWB) based anchors. One or more wayside units placed on or near a track may be configured to form a work zone network, based on ultra-wideband (UWB) communications, corresponding to a work zone in an area surrounding or in proximity to the one or more wayside units. When the work zone network is formed, at least one wayside unit of the one or more wayside units may be configured to obtain ranging information to a train traversing the track, based on communications of UWB signals with at least one train-mounted unit deployed on the train, and the one or more wayside units are configured to generate, based on the ranging information, notifications relating to the train and/or the work zone.

Systems and methods are provided for worker protection system with ultra-wideband (UWB) based anchors. One or more wayside units placed on or near a track may be configured to form a work zone network, based on ultra-wideband (UWB) communications, corresponding to a work zone in an area surrounding or in proximity to the one or more wayside units. When the work zone network is formed, at least one wayside unit of the one or more wayside units may be configured to obtain ranging information to a train traversing the track, based on communications of UWB signals with at least one train-mounted unit deployed on the train, and the one or more wayside units are configured to generate, based on the ranging information, notifications relating to the train and/or the work zone.

An exemplary lantern comprising a signal member which serves as a safety feature to warn workers operating in a railyard of dangerous or potentially dangerous conditions. An exemplary lantern comprising a breakaway handle mechanism that allows the handle of the lantern to break away from the body of the lantern. An exemplary lantern may comprise a ratcheting mechanism that allows the handle to rotate relative to the body of the lantern, thereby allowing the lantern to be arranged on the ground in a variety of different positions.