A photoacoustic measurement probe and a probe unit capable of preventing generation of artifacts in a photoacoustic measurement apparatus are obtained. In a photoacoustic measurement probe having a light emitting unit that emits measurement light toward a subject, an acoustic wave detection element that detects an acoustic wave emitted from a portion of the subject that has received the measurement light, and a housing which has a surface facing the subject at the time of use and in which the light emitting unit and the acoustic wave detection element are housed, at least one slit that is opened to the housing surface and that extends from the housing surface toward the inside of the housing is provided between the light emitting unit and the acoustic wave detection element.

A method of analysis using mass and/or ion mobility spectrometry or ion mobility spectrometry is disclosed comprising: using a first device to generate aerosol, smoke or vapour from one or more regions of a first target of biological material; and el mass and/or ion mobility analysing and/or ion mobility analysing said aerosol, smoke, or vapour, or ions derived therefrom so as to obtain first spectrometric data. The method may use an ambient ionisation method.

A method of analysis using mass and/or ion mobility spectrometry or ion mobility spectrometry is disclosed comprising: using a first device to generate aerosol, smoke or vapour from one or more regions of a first target of biological material; and el mass and/or ion mobility analysing and/or ion mobility analysing said aerosol, smoke, or vapour, or ions derived therefrom so as to obtain first spectrometric data. The method may use an ambient ionisation method.

A measuring unit (103) chronologically measures a heart rate or pulse rate of a measurement subject. A computing unit (104) obtains a statistic of measuring results measured by the measuring unit (103). The computing unit (104) obtains a statistic of a plurality of measuring results measured during a set period of time by the measuring unit (103) and stored in a storage unit. A correction unit (105) corrects a photoacoustic signal detected by a detection unit (102) based on the statistic obtained by the computing unit (104). The correction unit (105) corrects the photoacoustic signal that is detected by the detection unit (102) immediately after the latest value of the heart rate or pulse rate used in the calculation of the statistic by the computing unit (104) is measured. The correction unit (105) performs the correction by adding a value obtained by multiplying the statistic obtained by the computing unit (104) by a pre-set correction coefficient, to the photoacoustic signal detected by the detection unit (102).

Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.

Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.

An apparatus for performing ambient ionization mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped, coil-shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapor onto said collision assembly.

Systems and methods involving a control and processing system interfaceable with a device, a tracking system, and a data storage device, the control and processing system having a processor configured by a set of instructions storable in relation to a nontransient memory device to: identify the at least one device, via the tracking system operating with at least one of an electromagnetic system and a radiofrequency (RF) system, during a medical procedure; obtain an image of a region of interest associated with the medical procedure; process the image to identify a context measure associated with a current state of the medical procedure; obtain a parameter for adaptively configuring the device during the medical procedure, the parameter customizable based on the context measure, the parameter providable for the device according to a prioritized list, and the device reverting to a default configuration when another device is removed from the region of interest; and configure the device according to the parameter.

An apparatus is disclosed comprising a first device for generating aerosol, smoke or vapour from one or more regions of a target, an inlet conduit to an ion analyser or mass spectrometer, the inlet conduit having an inlet through which the aerosol, smoke or vapour passes, and a Venturi pump arrangement arranged and adapted to direct the aerosol, smoke or vapour towards the inlet.

An apparatus is disclosed comprising a first device for generating aerosol, smoke or vapour from one or more regions of a target, an inlet conduit to an ion analyser or mass spectrometer, the inlet conduit having an inlet through which the aerosol, smoke or vapour passes, and a Venturi pump arrangement arranged and adapted to direct the aerosol, smoke or vapour towards the inlet.