A method of guiding performance of an ultrasound imaging procedure, comprising: detecting at least a position of an ultrasound probe; determining a position of an imaging region of the ultrasound probe relative to a target based on the at least detected position of the ultrasound probe; displaying a figure representative of an imaging region together with a reference image associated with the target wherein the appearance of at least part of the figure is dependent on at least the determined position of the imaging region relative to the target; and updating the appearance of at least part of the figure as the ultrasound probe moves relative to the target.

An acoustic-wave measuring device includes: a support table having a support surface configured to support an examination subject, and an opening portion provided in the support surface to measure a predetermined examination site of the examination subject; a container located vertically below the support surface and capable of containing an acoustic matching material in a liquid or gel form; and a receiving element located vertically below the support surface and configured to receive an acoustic wave generated from the examination site, wherein a matching-material bag containing an acoustic matching material in a liquid or gel form or a matching gel having limited flowability and an acoustic control effect, and a placement unit for placement of the matching-material bag or the matching gel thereon are installable between the acoustic matching material contained in the container and the examination site.

A method of analyzing an image of a volume of tissue to determine a risk of developing breast cancer using a volume averaged sound speed within the volume. A method of determining a response to a treatment plan by determining a volume and a volume averaged sound speed of a region of interest within a volume of breast tissue and generating a combined metric from the volume and the volume averaged sound speed over the plurality of instances of time. A method of analyzing an image of a volume of tissue of a breast by applying a spatial filter to at least one ultrasound tomography image at the computing system and generating a stiffness map from the at least one ultrasound tomography image.

Systems and methods for deep tissue visualization using ultrasound and stereo imaging are provided. Various aspects of the present disclosure provide intraoperative identification of sub-tissue surface critical structures (e.g., identification of ureters, nerves, and/or vessels). For example, various surgical visualization systems disclosed herein can enable the visualization of one or more portions of critical structures below the surface of the tissue in an anatomical field in real-time. Such surgical visualization systems can augment the clinician's endoscopic view of an anatomical field with a virtual, real-time depiction of the critical structure as a visible image overlay on the surface of visible tissue in the field of view of the clinician.

Systems and methods for deep tissue visualization using ultrasound and stereo imaging are provided. Various aspects of the present disclosure provide intraoperative identification of sub-tissue surface critical structures (e.g., identification of ureters, nerves, and/or vessels). For example, various surgical visualization systems disclosed herein can enable the visualization of one or more portions of critical structures below the surface of the tissue in an anatomical field in real-time. Such surgical visualization systems can augment the clinician's endoscopic view of an anatomical field with a virtual, real-time depiction of the critical structure as a visible image overlay on the surface of visible tissue in the field of view of the clinician.

Provided are a composition for an acoustic wave probe which includes polysiloxane that has a vinyl group and a phenyl group, polysiloxane that has two or more Si—H groups in a molecular chain, a titanium oxide particle, and a silica particle, in which at least one of the titanium oxide particle (C) or the silica particle (D) is a particle subjected to surface treatment; a silicone resin for an acoustic wave probe; an acoustic wave probe; an acoustic wave measurement apparatus; an ultrasound diagnostic apparatus; an ultrasound probe; a photoacoustic wave measurement apparatus; and an ultrasound endoscope.

For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. Rather than the brute force approach of training the generator from 2D ICE images to output a 2D segmentation, the generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. Where sufficient ground truth data is not available, computed tomography or magnetic resonance data may be used as the ground truth for the sample sparse ICE volumes. The generator is trained to output both the 3D segmentation and a complete volume (i.e., more voxels represented than in the sparse ICE volume). The 3D segmentation may be further used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.

For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. Rather than the brute force approach of training the generator from 2D ICE images to output a 2D segmentation, the generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. Where sufficient ground truth data is not available, computed tomography or magnetic resonance data may be used as the ground truth for the sample sparse ICE volumes. The generator is trained to output both the 3D segmentation and a complete volume (i.e., more voxels represented than in the sparse ICE volume). The 3D segmentation may be further used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.

An ICG fluorescence image measured with an excitation light of 740 nm and a fluorescence of 845 nm is shown in FIG. 10, and an ICG fluorescence image measured with an excitation light of 780 nm and a fluorescence of 845 nm is shown in FIG. 11, respectively. As a result, it was observed that the ICG derivative RGD2-PPA-Cy accumulated in the tumor tissue 30 minutes after tail vein administration, regardless of whether the wavelength of the excitation light was 740 nm or 780 nm.

An ultrasonic device includes a driving circuit to provide drive power, a first transducer array to generate ultrasonic waves, the first transducer array being connected to receive power from the driving circuit, and a second transducer array to detect reflected or elicited ultrasonic waves incident on the device from a target and generate a signal based on those waves, the second transducer array being acoustically transmissive and disposed over the first transducer array such that the generated ultrasonic waves pass through the second transducer array. The second array is tuned to operate on top of the first. The functions of the two arrays may be reversed and the array tuned to operate with the first array receiving and the second array transmitting.