The invention relates to an ultrasound device (1) insertable into a patient body (2) for in-situ ultrasound imaging. The device (1) comprises an ultrasound transducer device (4) having an imaging surface (5) for contacting tissue to be imaged and being attached to a support element (21). The support element (21) comprises a gripping member (21, 23) having a gripping surface configured for being at least temporarily affixed to the tissue, the gripping member (21) at least partly surrounding the imaging surface (5) of the ultrasound transducer device (4) and the gripping surface (23) being made from a deformable material. By means of the gripping member (21, 23), the device (1) can automatically be held at an imaging position. Further, the device (1) does not require an elongated shaft for manipulating the ultrasound module, which could interference with other surgical devices.

A system may include an ultrasound probe and a controller unit configured to communicate with the ultrasound probe. The controller unit may be further configured to select an aiming mode for an ultrasound probe; detect a target of interest; determine a centroid for the detected target of interest; display a center indicator based on the determined centroid; detect that the center indicator is within a threshold number of pixels or distance of a centerline of a field of view of the ultrasound probe; and highlight the generated center indicator, in response to detecting that the center indicator is within the threshold number of pixels or distance of the centerline.

In some aspects, the described systems and methods provide for a method comprising transmitting to a brain of a patient, with at least one transducer, acoustic signals. The method further comprises receiving from the brain, with the at least one transducer, data acquired from the brain including information related to standing waves, distribution of acoustic modes, frequency response, and/or impulse/transient response. The method further comprises determining, from the acquired data, intracranial pressure of the person.

In some aspects, the described systems and methods provide for a method comprising transmitting to a skull of a patient, with at least one transducer, acoustic signals. The method further comprises receiving from the skull, with the at least one transducer, data acquired from the skull including information related to guided waves, distribution of acoustic modes, frequency response, and/or impulse/transient response. The method further comprises determining, from the acquired data, intracranial pressure of the person.

In some aspects, the described systems and methods provide for a method comprising transmitting, with at least one transducer, acoustic signals to a brain of a patient, wherein the at least one transducer is configured to induce excitation of a plurality of acoustic modes. The method further comprises receiving, with the at least one transducer, data acquired from the brain including information related to standing waves, frequency response, impulse/transient response, and/or distribution of acoustic modes. The method further comprises determining, from the acquired data, a distribution of intracranial pressure within the brain of the person.

In some aspects, the described systems and methods provide for a method comprising transmitting to a brain of a patient, with at least one transducer, acoustic signals. The method further comprises receiving from the brain, with the at least one transducer, data acquired from the brain including information related to standing waves, distribution of acoustic modes, frequency response, and/or impulse/transient response. The method further comprises detecting, from the acquired data, a seizure of the person.

In some aspects, the described systems and methods provide for a method comprising transmitting to a brain and/or skull of a patient, with at least one transducer, acoustic signals. The method further comprises receiving from the brain and/or skull, with the at least one transducer, data acquired from the brain and/or skull including information related to standing waves, guided waves, distribution of acoustic modes, frequency response, and/or impulse/transient response. The method further comprises determining, from the acquired data, presence of a tumor within the brain of the person.

In some aspects, the described systems and methods provide for a method comprising transmitting, with at least one transducer, acoustic signals to a brain of a patient, wherein the at least one transducer is configured to induce excitation of a plurality of acoustic modes. The method further comprises receiving, with the at least one transducer, data acquired from the brain including information related to standing waves, frequency response, impulse/transient response, and/or distribution of acoustic modes. The method further comprises determining, from the acquired data, a location of a seizure site within the brain of the person.

For longitudinal monitoring of a patient using quantitative ultrasound (QUS), one or more indicators of region of interest (ROI) position relative to the patient and one or more images from a past QUS imaging for the patient are stored. The indicator is in addition to an image with the ROI. For subsequent QUS imaging of the patient, the indicator is used to position the ROI. In QUS monitoring, a same or fixed anatomy is monitored from examination-to-examination based on placement of the ROI using a displayed indicator for the previous placement.

A monitoring apparatus for monitoring a blood pressure information of a subject is disclosed. The monitoring apparatus comprises an ultrasound transducer for emitting ultrasound waves to a volume of the subject that includes a blood vessel and for receiving ultrasound waves from said volume of the subject, and for providing a first signal on the basis of ultrasound waves received from the volume of the subject. A light source is included for emitting light to the subject and a light sensor is included for detecting light received from the subject and for providing a second signal on the basis of the light received from a skin of the subject. The monitoring apparatus comprises a processing unit for determining: i) a time of arrival of a cardiac pulse in the blood vessel based on the first signal, ii) a point in time when the cardiac pulse reaches the skin of the subject based on the second signal, iii) a pulse transit time between the time of arrival of the cardiac pulse PPG in the blood vessel and the point in time when the cardiac pulse reaches the skin of the subject; and iv) the blood pressure based on the pulse transit time.