Described herein are implantable devices configured to detect an electrophysiological signal. Certain exemplary implantable devices comprise a first electrode and a second electrode configured to engage a tissue and detect an electrophysiological signal; an integrated circuit comprising a multi-transistor circuit and a modulation circuit configured to modulate a current based on the electrophysiological signal; and an ultrasonic transducer configured to emit an ultrasonic backscatter encoding the electrophysiological signal from the tissue based on the modulated current. Also described herein are systems that include one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Further described are computer systems for operating one or more implantable devices, and methods of detecting an electrophysiological signal in a tissue.

A mechanism is provided in a data processing system comprising a processor and a memory, the memory comprising instructions that are executed by the processor to specifically configure the processor to implement a medical imaging story board creation engine. The medical imaging story board creation engine executing in the data processing system receives a patient data structure comprising a medical imaging study comprising a plurality of electronic medical images. The medical imaging story board creation engine analyzes the patient data structure to determine a modality of the medical imaging study. The medical imaging story board creation engine determines, based on the determined modality of the medical imaging study, for each electronic image in the medical imaging study, at least one of an image mode or viewpoint. The medical imaging story board creation engine performs a saliency feature extraction operation on the electronic medical images in the medical imaging study based on the image mode or viewpoint of each of the electronic medical images. The medical imaging story board creation engine selects a subset of electronic medical images based on results of the saliency feature extraction. The medical imaging story board creation engine generates and outputs a collection of selected electronic medical images based on the selection of the subset of electronic medical images to form a medical imaging story board.

Provided are an ultrasound diagnosis apparatus for displaying shear wave data relating to an object and an operation method thereof. The ultrasound diagnosis apparatus includes a processor configured to obtain the shear wave data of the object with respect to each of a plurality of cross sections spaced apart by a predetermined distance and set a region of interest (ROI) in a reference cross section among the plurality of cross sections; and a display displaying a graphic user interface (GUI) representing shear wave data of a region corresponding to a same location as that of the ROI in the plurality of cross sections along a depth direction.

Described herein is an implantable device comprising a radiation-sensitive element (such as a transistor) configured to modulate a current as a function of radiation exposure to the transistor; and an ultrasonic device comprising an ultrasonic transducer configured to emit an ultrasonic backscatter that encodes the radiation exposure to the transistor. Further described herein is an implantable device comprising a radiation-sensitive element (such as a diode) configured to generate an electrical signal upon encountering radiation; an integrated circuit configured to receive the electrical signal and modulate a current based on the received electrical signal; and an ultrasonic transducer configured to emit an ultrasonic backscatter based on the modulated current encoding information relating to the encountered radiation. Further described are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also describe are computer systems for operating implantable devices, methods of detecting radiation, methods of treating a solid cancer in a subject, and methods of monitoring a subject for recurrence of a solid cancer.

The invention relates methods of reducing the risk or preventing the occurrence of an adverse event (AE) or a serious adverse event (SAE) associated with a medical treatment comprising inhalation of nitric oxide.

An ultrasound diagnosis apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to detect a saturation region of a signal based on an ultrasound wave received by an ultrasound probe; and to correct a first signal including an odd-numbered order harmonic component of the saturation region, on a basis of a second signal including an even-numbered order harmonic component of the saturation region.

This disclosure generally relates to systems and methods for facilitating determination of morphology (e.g., shape) and structure (e.g., size, rigidity) and/or penetrating channels (e.g., microchannels) of occlusions (e.g., clots, fluid obstructions, tumors, chronic total occlusions) involving magnetic particles (e.g., nanoparticles, microparticles) controlled by an external magnetic control system.

In one embodiment, a superlens is used to sub-diffraction-limit focus a magnetic field within a volume. A local magnetic field intensity maximum, or hotspot, is thereby created that is focused in two spatial directions substantially parallel to the superlens. The hotspot extends from the superlens through one or more coplanar layers of the volume. An electric field is superimposed over the magnetic field within the volume to be imaged. The superposition of electric and magnetic fields induces localized Lorentz forces. The modulation of the magnetic and/or electric field causes the portion of the volume in the hotspot to vibrate and emit acoustic signals at a frequency suitable for acoustic imaging. An acoustic transducer receives the emitted acoustic signals. The location from which the acoustic signals are emitted is constrained in two dimensions by the superlens. Time-gating the acoustic signals received from the hotspot is used to localize the received acoustic signals in the third dimension.

A method for quantifying an amount of fat contained in a liver or other tissue of a subject in vivo includes varying the temperature of a target area in a subject, imaging thermal strain of the target area using an ultrasound scanner, and quantifying the amount of fat in the targeted area based on the thermal strain imaging. In some embodiments, the thermal strain imaging is performed using high-resolution, phase-sensitive speckle tracking to differentiate between fat-based tissue and water-based tissue.

An ultrasonic diagnostic device according to an embodiment includes processing circuitry. The processing circuitry estimates a health state on the basis of a measurement value measured using ultrasonic image data. The processing circuitry determines an additional examination used to diagnose the health state, on the basis of the estimated health state. The processing circuitry outputs information indicative of the health state and the additional examination.