A rapid diagnostic test device uses driven flow technology to significantly expedite the testing time of a sample. The rapid diagnostic test device can be used to analyze liquids, such as some body fluids, by using labeled molecular affinity binding, such as immunochromatography. The test device can detect an analyte, such as an antibody or antigen, which may indicate a particular condition, the presence of a particular drug, or the like. The device includes an inner member that receives the body fluid. Dripping holes in the inner member, or a sloped surface, creates a stream force of the body fluid against the sample pad of the test strip. A portion of the stream force of the body fluid is directed upward toward the conjugate pad to push the antibody/body fluid sample onto the membrane of the test strip.

An alcohol and drug intervention system and method, comprising: a server component; and a mobile application component wirelessly coupled to the server component; wherein the server component and the mobile application component are collectively operable for, in an interactive manner, receiving input from a user and presenting the user with output based on the input received from the user, wherein the input received from the user comprises one or more of personal information, activity information, and activity related to alcohol and/or drug use, and wherein the output presented to the user comprises one or more of coaching information and counseling information. Optionally, the system further comprises a testing device coupled to the mobile application component and adjusting one or more of the coaching and counseling information based on results obtained from the testing device.

A locomotive is disclosed. The locomotive includes a car body, including an operator cabin, a power source, and an operator health monitor within the operator cabin, the operator health monitor configured to monitor at least one health condition associated with the operator and configured to generate an operator health signal associated with the at least one condition. The locomotive includes an operator warning system within the operator cabin, configured to present the operator with an operator warning in response to an operator warning signal, and an electronic controller. The electronic controller may be configured to determine an operator fatigue score based on, at least, the operator health signal, determine if the operator fatigue score exceeds a warning threshold, and transmit the operator warning signal to the operator warning system if the operator fatigue score exceeds the warning threshold.

The present invention generally relates to systems and methods for monitoring and/or providing feedback for drugs or other pharmaceuticals taken by a subject. In one aspect, the present invention is directed to devices and methods for determining a species within the skin of a subject; and producing feedback to a subject based on the determination of the species. The feedback may be, for example, visual, audible, tactile, a change in temperature, etc. In some cases, information regarding the determination of the species may be transmitted to another entity, e.g., a health care provider, a computer, a relative, etc., which may then provide feedback to the subject in some fashion. In some cases, the feedback may be directly indicative of the species, e.g., whether the species is present, the concentration of the species, whether a by-product of a reaction involving the species is present, whether a compound affected by the species is present, etc. However, the feedback may also be indirect in some embodiments. For example, the subject may be presented with an external reward, e.g., based on the determination of the species within the skin. For instance, a reward such as cash, coupons, songs, discounts, personal items, etc., may be offered based on the level of compliance of the subject. Still other aspects of the invention are generally directed to kits involving such devices (with or without the drug to be monitored), methods of promoting such systems, or the like.

An apparatus for testing a fluid sample including a sample receiving member having an opening for receiving a fluid sample, wherein the sample receiving member comprises a sample collection chamber; a sample retention member, in fluid communication with the sample collection chamber, to retain a portion of the fluid sample; and at least one test strip, in fluid communication with the sample collection chamber, to indicate the presence or absence of at least one analyte in the fluid sample.

In devices that determine levels of substance use, a substance level in a test sample provided to the testing device by a test subject is determined. A sequence of images are captured to include a portion of the face of the test subject providing the test sample and a display of the testing device. A value indicative of the substance level detected within the test sample is determined. A validity indicator indicating validity of the value indicative of the substance level is determined. A current location is determined. The value indicative of the substance level, the validity indicator, and the current location are sent to a remote server.

A method of producing a biologic liquid sampling tablet is disclosed and includes molecularly imprinting a polymer over a matrix of an analyte of interest for biological testing; and removing the matrix from the imprinted polymer to form a porous tablet. The tablet is sized to be inserted in an ampoule or human oral cavity.

A system for accident detection or detecting an unsafe driving condition in a vehicle including a device that measures and transmits at least one output signal; at least one remote device configured to receive, record, and/or display the at least one output signal from the device; a computing device configured to receive the at least one output signal from the device and display the at least one output signal in real-time; and a graphical user interface on the computing device that allows an emergency response professional to view and customize options for monitoring the at least one output signal, wherein the device, the at least one remote device, and the computing device are communicatively connected to each other via a communications network.

A vehicle immobilization system includes a detection element operable to detect a level of an intoxicant in a user's breath. A control module is operable to receive a signal from the detection element indicating the level of intoxicant in the user's breath, and to selectively restrict operation of a vehicle based on the level of intoxicant in the user's breath exceeding a threshold. A wireless relay is operable to replace a standard relay in the vehicle, and to wirelessly communicate with the control module such that the control module is operable to control the wireless relay to selectively restrict operation of the vehicle.

The present invention provides an apparatus for detecting the presence or absence of an analyte in liquid sample, including: a collection chamber, including an opening for collecting a liquid sample; a testing element for testing the analyte in liquid sample; and a cover for covering the opening of the collection chamber; wherein the apparatus further includes a prompting device for prompting if the cover is covered to a specified location, and the prompting device shall at least includes a first element and a second element, the first element is in contact with the second element, wherein one element vibrates to produce a sound. In some preferred ways, the second element produces friction with the first element, to cause one of the elements to generate vibrations. The apparatus in the present invention can allow the prompting sound to be clear and loud.