The present invention provides an apparatus for detecting the presence or absence of an analyte in liquid sample, including: a collection chamber, including an opening for collecting a liquid sample; a testing element for testing the analyte in liquid sample; and a cover for covering the opening of the collection chamber; wherein the apparatus further includes a prompting device for prompting if the cover is covered to a specified location, and the prompting device shall at least includes a first element and a second element, the first element is in contact with the second element, wherein one element vibrates to produce a sound. In some preferred ways, the second element produces friction with the first element, to cause one of the elements to generate vibrations. The apparatus in the present invention can allow the prompting sound to be clear and loud.

The application relates to a chemical monitoring system comprising a skin patch for detecting an analyte in perspiration and a processor adapted to receive parameter data and to return an output indicative of a presence of an analyte in a subject's body based on the parameter data. The skin patch (100) includes a first layer (105) permeable to perspiration; a second layer (110) coupled to the first layer, the second layer being adapted to receive the perspiration; wherein a property of the second layer changes upon receiving the analyte; an electrical detector coupled to the second layer, adapted to detect parameter data indicative of the property of the second layer; and a flexible electronic circuit (140) coupled to the second layer, comprising a readout circuit for reading parameter data from the electronic detector and a transmitter adapted to transmit the parameter data to a processor.

A sweat sensing system comprises a mesh for location over a sweat surface on which sweat is formed or collected, and a vibration system for vibrating the mesh to nebulize sweat droplets. The nebulized sweat droplets are condensed on a sensing surface, and a sweat sensor performs biomarker sensing of the sweat at the sensing surface.

An apparatus for collecting and testing a sample is provided. The apparatus includes a test cavity and a collecting component. The test cavity is connected to the collecting component and the test cavity and the collecting component are in a liquid communication. An inner wall of the test cavity is provided with a first step. The collecting component includes a collecting rod and an absorbing element sleeved on the collecting rod. A connecting end of the collecting rod is provided with a barb. A tail end of the barb is tapered. The barb at the connecting end is clamped to the first step to connect the test cavity with the collecting component. A collecting and testing apparatus with an integrated structure is provided. The integrated structure integrates the collection and test of a sample, reduces a product structure and an operation difficulty of subjects.

Multiplexed transdermal extraction and detection devices and systems for non-invasive monitoring of substances, such as glucose, are disclosed, as are methods of using these devices for substance monitoring in subjects.

A sweat sensing device includes a plurality of sweat collection pads communicating with a sensor. Each of the pads is activated by a timing circuit which allows one or more of the pads to be activated at a selected time and subsequent deactivated after a defined period of time. This allows for selective collection of sweat from a plurality of pads over a prolonged period of time. An impedance measuring circuit can be employed to determine if one or more of the pads becomes disconnected, in order to avoid irritation. Further, the devices can use a common microfluidic device which both transports sweat activating substance, such as pilocarpine, to the surface of the skin and directs sweat away from the skin to a sensing device.

A method and system for monitoring a user's intoxication including receiving a set of signals, derived from a set of samples collected from the user at a set of time points; providing a sobriety task to the user proximal to a time point of the set of time points; generating a performance dataset characterizing performance of the sobriety task by the user; receiving a supplementary dataset characterizing a demographic profile of the user and/or a physiological state of the user; determining a set of values of an intoxication metric, derived from the set of signals; generating a predicted temporal profile of the intoxication metric for the user based upon the set of values, the set of time points, and the supplementary dataset; generating an analysis of the user's sobriety based upon the performance dataset and the predicted temporal profile; and providing a notification to the user based upon the analysis.

A breath collection device can detect changes associated with pathogenesis of a disease, such as COVID-19, including biomarkers of immune response for respiratory symptoms, central nervous system injury, and/or peripheral nervous system injury in user breath and/or odor. The breath collection device can detect concentrations of alcohol, acetone, and carbon monoxide in user breath samples. A breath sample can be received in an internal bladder of the device for sensor analysis. Concentrations of alcohol, acetone, and carbon monoxide can be determined by calibrated calculation. A detection method for alcohol, acetone, and carbon monoxide can provide a non-invasive, rapid, and selective detection of gases in a variety of applications in virus detection as well as agricultural and homeland security.

A system for obtaining clearance comprises a mechanism to identify the user and generate an identification signal; an analytical toilet comprising a bowl to receive excreta from the user; an analyzer configured to analyze the sample to detect one or more antibodies in a sample of the excreta or sputum and to generate an analysis signal; a processor configured to receive the identification signal and the analysis signal; determine therefrom the status of the user with respect to the one or more antibodies; and transmit a report to an authority, the report comprising the identity and the status of the user with respect to the antibodies detected. A method for obtaining clearance comprises linking a user to an analytical toilet; receiving a sample of excreta from the user in the analytical toilet; analyzing the sample of excreta in an analytical toilet to detect one or more antibodies; processing results from the analytical toilet and determining the status of the user with respect to the antibodies detected; submitting the identity and the status of the user with respect to the antibodies detected to an authority.

A system for tracking an infectious disease in a population comprising an analytical toilet configured to analyte a sample of excreta or sputum from an individual in the population, to thereby determine whether the individual is positive for the infectious disease; a processing module configured to link each positive result with the date and time it was determined; a communication module for communicating data comprising the linked positive result and date and time to an authority, thus providing the authority with information required to track the infectious disease in the population is disclosed.