A kit and method for intrauterine insemination is provided. The steps of the method include self-monitoring of a menstrual cycle of a patient by said patient, making an abrasion on the endometrial lining of a uterus of the patient following menstruation by the patient, predicting timing of ovulation by using an ovulation monitoring system or inducing ovulation; preparing sperm for insemination during ovulation by the patient, guiding an intrauterine insemination catheter accompanied by a cervical shield into the patient, depositing a semen sample into the uterine cavity or cervical canal, removing the catheter from the body of the patient while using a holding tool to hold the cervical shield in place at the entrance to the uterine cavity, and leaving the cervical shield in place for a predetermined time period.

An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.

A urine analysis device includes a case configured to be positioned entirely within a toilet, the case having a front face for receiving a stream of urine directly from a user urinating on the toilet a rear face opposite the front face, and a collection port, disposed on either the front face or the rear face, wherein the case contains a test assembly configured to perform an analysis on urine collected through the collection port.

Provided herein are systems and methods that use an electrochemical aptamer-based (EAB) biosensor to detect a plurality of hormone and/or analyte that can be used for fertility and pregnancy monitoring.

Methods, systems, and devices for menstrual cycle onset prediction are described. The method may include receiving physiological data associated with a user from a wearable device, the physiological data including at least temperature data. The method may include fitting the received temperature data to a trigonometric or polynomial function including a plurality of features and calculating a duration between the plurality of features and a corresponding plurality of menstrual cycle onset days. The method may include estimating a future menstrual cycle onset day that the user experiences a first day of a menstrual cycle based on applying the duration to a most recent feature of the trigonometric or polynomial function. In some cases, the method may include causing a graphical user interface of a user device to display an indication of the estimated future menstrual cycle onset day.

Physiological parameters such as respiratory rate and/or heart rate variability can be measured over time for a user and correlated to physiological and/or hormonal cycles such as the menstrual cycle. By determining the phase of such a cycle in this manner, an automatic coach for the user can recommend phase-specific adjustments to activities such as sleep and exercise.

The invention relates to methods of increasing the genetic progress of a line, breed or herd of swine through the use of sex-selected sperm cells in artificial insemination techniques. The invention also encompasses methods of artificially inseminating a swine via deep intrauterine catheter or via a laparoscopic procedure, which allow the use of reduced doses of sex-selected sperm cells.

Provided herein are devices and methods for monitoring biofluids related to ovulation. Such devices include the use of electrochemical aptamer-based (EAB) sensors.

A urine analysis device for positioning within a toilet includes a test assembly having at least one rotatable holder including a plurality of test strips attached to the rotatable holder; an injector configured to inject a controlled volume of urine onto at least one of the test strips; and an analysis system configured to detect a result of urine injection onto the test strip.

A hearable comprises a wearable structure including a speaker, a sensor, and a temperature compensating circuit which measures temperature in an environment of the sensor. A portion of the wearable structure, which includes the sensor and temperature compensating circuit, is disposed within a user’s ear when in use. A sensor processing unit which is communicatively coupled with the temperature compensating circuit: acquires temperature data from the temperature compensating circuit while the portion of the wearable structure is disposed within the ear of the user; builds a baseline model of normal temperature for the user; and compares a temperature measurement acquired from the temperature compensating circuit to the baseline model. In response to the comparison showing a deviation beyond a preset threshold from the baseline model, the sensor processing unit generates a health indicator for the user which is used to monitor an aspect of health of the user.