The present disclosure provides for acid-resistant capsules comprising compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (GI) tract, including a colon. Compositions of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated traveler's diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection.

In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (GI) tract, including a colon; and methods for making and using them. In alternative embodiments, compositions and methods of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated travelers diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection. In alternative embodiments, the invention provides pharmaceuticals and products (articles) of manufacture for delivering these compositions and formulations to an individual, e.g., a human or an animal. The invention also provides devices for delivering a fecal material to a patient.

A specimen collection and delivery apparatus for collecting clinical specimens and delivery of samples thereof to, e.g., microfluidic testing devices for diagnostic analysis is disclosed. The specimen collection and delivery apparatus includes a closure housing for coupling with a sample tube at one end, an open luer for coupling with a complementary luer on a microfluidic device at the other end, and a filter matrix disposed in the interior. The filter matrix is air permeable and liquid impermeable at atmospheric pressure and prevents sample from flowing through the open luer end when coupled to a sample tube containing a specimen. Under vacuum, the liquid sample fraction of the specimen can be drawn through the filter matrix and into the microfluidic testing device through the luer connection for diagnostic analysis.

A device for determining physiological data through analysis of human excrement in a toilet using at least one indicator and/or sensor, and a method for determining physiological data by analysis of human excrement in a toilet by measurement of urine and/or stool values, in order to achieve maximally universal use of the device, including in a wide variety of toilet designs, with reasonable design effort and manageable costs. A measurement system, in which an indicator or sensor can be brought into a measurement position, in which sufficient contact with the urine or stool to be examined occurs via an arm for each measurement, wherein the indicator or sensor is/are designed as (an) independent unit(s), and by a corresponding method in which a plurality of previously determined values are measured and then processed further and forwarded as applicable.

A non-invasive system for sampling gastrointestinal microbiota with their associated environment for discovery, characterization, medical research, diagnostics, and treatment using an ingestible, non-digestible sampling capsule. The capsule device, with ports open for acquiring a sample of gastrointestinal microbiota and content, is placed inside an immediate or delayed release capsule. When the outer capsule dissolves according to its specifications, enteric fluid and content enters the sampling capsule through the ports triggering a hydrophilic stop to release a pulling force to close the ports by enveloping the capsule outer casing over the inner casing, capturing the sample, and holding it sealed until it completes passage through the digestive track, and is recovered from feces for analysis.

A toilet is disclosed. The toilet has a bowl adapted to receive feces, a shelf for receiving feces in the bowl, a mechanism that places a consumable material on the shelf between uses of the toilet, and a removal mechanism for removing the feces and the consumable material from the bowl. The consumable material on the shelf is to separate feces from the shelf.

Disclosed is an integrated device for faeces sampling and occult blood detection, which has functions of quantitative collection, dissolution, filtration, detection with immune test strips of the faecal sample, and is convenient to carry and operate, and the device does not leak any liquid during storage, transportation and detection. The device can accurately collect a constant sample with no pollution and leakage, and can quickly determine results of occult blood without the aid of other items. The device can detect faecal occult blood at any time and at any place, can help to overcome the problem of low rate of inspection due to the inconvenience of faeces submission and inspection, further promote the detection of faecal occult blood, and can improve the early diagnosis and screening rate of colorectal cancer of the population.

A system and a method for treatment of a disorder in a gastrointestinal tract of a subject, using a treatment protocol, the treatment protocol being based at least in part on data relating to other subjects and their responses to treatment with various treatment protocols.

In the inside of a container main body having a first surface into which a stool sampling rod is inserted and a second surface opposed to the first surface, a storage space for storing a storage solution has a wide portion having a width wider than that of the first surface side at an end portion on the second surface side, and the wide portion has a width which enables receiving the nozzle inserted from a first position shifted in the width direction with respect to a coaxial position on an extension line of an axis of the stool sampling rod, and allows the parts of the nozzle and the stool sampling rod to overlap each other in the longitudinal direction.

An analytical toilet is disclosed. The analytical toilet includes a bowl adapted to receive excreta and a detection system to detect a virus, such as a coronavirus. The analytical toilet presents a sample extracted from feces to the detection system and the detection system creates a signal indicating whether or not a coronavirus is present in the sample. Preferably, the detection system comprises a quantitative PCR instrument and a fluorimeter.