Passive devices for non-invasive gastrointestinal (GI) sampling are disclosed. In some embodiments, a device includes a capsule housing containing an absorbent sampling hydrogel. The capsule may be ingested by a patient and subsequently travel through the GI tract. Once the capsule reaches a desired location in the GI tract, GI fluid may flow into the capsule through a sampling aperture of the capsule. The fluid may be absorbed by and stored within the sampling hydrogel for subsequent analysis, and the absorption of the fluid may cause the sampling hydrogel to expand within the capsule. The capsule may further include a sealing member positioned between the sampling hydrogel and the sampling aperture, and the expansion of the sampling hydrogel may press the sealing member against the sampling aperture to seal the capsule.

A catheter for isolating a region in a hollow organ of a mammal, having an elongate body designed to be inserted into a lumen of a mammal hollow organ and equipped with two balloons, the balloons being configured to be inflated to isolate an interior of the hollow organ therebetween; wherein a functional channel extending in the body has a functional opening provided in the body between the balloons; and wherein the functional channel is designed to allow a negative pressure to be produced in the isolated interior to take a biological fluid or biological gaseous medium therefrom or to allow a liquid or gaseous medium to be supplied to the isolated interior; and wherein another channel extending in the body is provided at opposite ends with an inlet and an outlet provided both in the body outside of the body part defined by the balloons.

A system for verifying a sample volume includes a sample reservoir and a volumetric verification device. The sample reservoir defines an inner volume and is configured to receive a volume of bodily fluid. The inner volume of the sample reservoir contains an additive. The volumetric verification device includes a first indicator and a second indicator. The volumetric verification device is configured to selectively engage the sample reservoir to (1) place the first indicator in a first position along a length of the sample reservoir such that the first indicator is substantially aligned with a surface and/or meniscus of the additive and (2) place the second indicator in a second position along the length of the sample reservoir such that the second indicator is substantially aligned with a predetermined fill volume when bodily fluid is transferred to the inner volume.

An endoscope (1) having a suction channel and a suction connector in communication with said suction channel, and a working channel through which a liquid may pass. A valve for diverting the suction through the sampling device through a sample container is provided. The endoscope (1) further includes an actuator (7) for propelling the liquid through said working channel.

A nasal irrigation diagnostic assembly comprising an irrigation device including a fluid collection portion structured to retain a biological sample, in the form of waste solution from the nasal cavity resulting from irrigation. A detection member disposed on said irrigation device is exposed to the biological sample and is structured to determine the existence of at least one analyte within the biological sample of the waste solution. The detection member comprises a plurality of detection zones individually structured to analyze the biological sample upon engagement therewith, wherein said plurality of zones include at least a reaction zone and a detection zone, which respectively include reagents cooperatively and collectively formulated to detect the existence of the at least one analyte within biological sample of the waste solution. A control zone may also be included to indicate the intended operability of at least the detection member.

A device for collecting, preserving and storing a sample of biological fluid comprising a porous medium for collecting and maintaining the membrane integrity of the eukaryotic cells contained in the sample, and their constituents is disclosed, the medium comprising at least 80% by weight of artificial components, advantageously at least 85%, preferably at least 90% of a total weight of the medium; and having a mean flow pore size (MFP) of at least 3 μm.

In some embodiments, a device may include an intraventricular access device and an infusion device. The intraventricular access device may include more than one catheter and a container. In some embodiments, the catheter may include an aspiration lumen and an infusion lumen. A distal end of the intraventricular portion of the catheter may be positionable, during use, in a subject's brain fluid. In some embodiments, the container may be coupled to a proximal end of the aspiration lumen. The proximal end of the aspiration lumen may be in fluid communication with the container. The proximal end of the infusion lumen may be in communication with an infusion pump. In some embodiments, the device inhibits cross contamination between a first fluid in the aspiration lumen and a second fluid in the infusion lumen. In some embodiments, the container may include a barrier positioned between a proximal opening of the aspiration lumen and at least a portion of the infusion lumen adjacent to and/or associated with the container. The barrier may inhibit penetration of a surgical instrument.

A sample capture and testing system can include a primary receptacle for receiving a fluid sample, where the primary receptacle has a sensor for label-free detection of an analyte disposed at one side. The primary receptacle can be incorporated in a needle for in vivo capture and testing of a sample. The primary receptacle can be incorporated into a specimen container and used as part of a point of care device.

A sampling device (9) for the use with an endoscope (1) having a suction channel and a suction connector (4) in communication with said suction channel. The sampling device (9) is adapted for connection to the suction connector (4) and said sampling device (9) is adapted for connection to a vacuum source. The sampling device (9) is adapted for forming a rigid connection with said endoscope (1) when connected to the suction connector thereof (4).

A bodily-fluid transfer device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.