A device for determining physiological data through analysis of human excrement in a toilet using at least one indicator and/or sensor, and a method for determining physiological data by analysis of human excrement in a toilet by measurement of urine and/or stool values, in order to achieve maximally universal use of the device, including in a wide variety of toilet designs, with reasonable design effort and manageable costs. A measurement system, in which an indicator or sensor can be brought into a measurement position, in which sufficient contact with the urine or stool to be examined occurs via an arm for each measurement, wherein the indicator or sensor is/are designed as (an) independent unit(s), and by a corresponding method in which a plurality of previously determined values are measured and then processed further and forwarded as applicable.

The present application discloses a variety of airway sampling devices and associated methods. According to an embodiment, an airway sampling device for taking a sample from a subject's airway is provided with a handle to be gripped by a user when taking the sample and a sampling head carried by the handle, the sampling head comprising a cavity with an opening for entry by the sample and a sample collection membrane located within the cavity for receiving the sample.

Assistive apparatuses or devices, kits, and methods for assisting with removal of a biological sample from an intraosseous device are described. Some of the present assistive apparatuses comprise: a body including a first end and a second end, and defining a channel with a first portion having a first transverse dimension, a second portion disposed between the first portion and the second end and having a second transverse dimension that is smaller than the first transvers dimension, and a longitudinal axis extending through the first portion and the second portion, the body further including a protrusion extending laterally outward relative to the longitudinal axis; where the channel is configured to receive a portion of an intraosseous device having a hub and a cannula extending from the hub, with the first portion of the channel receiving a part of the hub, and the second portion of the channel receiving a part of the cannula while preventing passage of the hub through the second portion.

An endocyte cannula is designed to provide improved and more productive Pap smear tests. The endocyte cannula includes a proximal portion and a distal portion. The proximal portion may include a fitting to connect to a user-actuated tool, such as a syringe. The distal portion may include a corkscrew feature or a lateral wing feature to facilitate movement of the cannula through dense tissue as well as provide scraping or brushing capabilities. The shaped scraping or brushing features may be provided on an attachment that is attachable to a shaft of the endocyte cannula. The attachments may allow customization of the endocyte cannula based on the physiology and anatomy of a patient. The distal portion may further include a plurality of apertures to aspirate mucus and reduce the risk of trauma or perforation. The apertures may extend outside of the attachment or shaped scraping or brushing features, and the distal portion may be narrower than the shaped scraping or brushing features to facilitate access into the endocervical canal and aspiration and collection of a cell sample.

A biological sample collection system can include a sample collection vessel having a closed first end and an open second for receiving a biological sample. The system can additionally include a sealing cap configured to associate with the sample collection vessel, a reagent chamber secured within an interior space of the sealing cap and retaining a measure of sample preservation solution, a shim circumferentially associated with a proximal end of the reagent chamber and spanning the distance between the reagent chamber and the interior sidewall of the sealing cap, and a plug having a diaphragm configured to selectively engage the shim and form a seal for retaining the sample preservation solution within the reagent chamber. Associating the sealing cap with the sample collection vessel displaces the diaphragm from the shim and breaks the seal formed therebetween, opening a fluid path between the reagent chamber and the sample collection chamber.

A multidirectional device for percutaneous procedures. The multidirectional device includes an operation chamber connected to a first end of a sheath via a hinge. A hinge system is operably connected to the operation chamber and allows for multidirectional movements of an operation apparatus disposed within the operation chamber. A housing is disposed on a second end of the sheath, wherein the housing includes controls for the hinge system. A main control system is operably connected to the housing to perform all hinge movement and housing functions and can be accessed remotely by a doctor performing the procedure. In some embodiments, the main control system is integrated into a CT or MRI scanner and is capable of being electronically navigated by artificial intelligence, convolutional neural networks, machine learning, autopilot navigation system, and the like. In other embodiments, a robot is used to control the movements of the multidirectional device.

Collection devices with valves for liquid specimens are disclosed. In an embodiment, the disclosure provides a collection device including a reservoir having a sealed cavity, the sealed cavity being under a negative pressure; a delivery tube in communication with the sealed cavity of the reservoir and having a delivery inlet, a delivery outlet, and a valve disposed between the delivery inlet and the delivery outlet, the valve being configured to control the communication and blocking between the delivery inlet and the delivery outlet, and an angle being formed by an extension line of the delivery inlet an extension line of the delivery outlet; and a piercing component for piercing a tissue is connected with the delivery inlet of the delivery tube.

A biopsy device includes a body, a needle, a cutter, a tissue sample holder, and a gate assembly. The needle extends distally from the body. The cutter is longitudinally translatable relative to the needle and defines a cutter lumen. The tissue sample holder is coupled proximally relative to the body. The cutter lumen of the cutter defines at least a portion of a fluid conduit extending between the cutter and the tissue sample holder. The gate assembly is configured to selectively arrest movement of a tissue sample holder within the fluid conduit between the cutter and the tissue sample holder.

The present invention relates to systems, devices, kits, and methods employing liquid activated devices and systems. In certain embodiments, the liquid activated devices comprise a base substrate and a chamber sealing system (CSS) and/or a sealed reservoir system (SRS). In some embodiments, the CSS is sealed inside the reservoir of the SRS by a liquid degradable membrane. In particular embodiments, a liquid (e.g., saliva) un-seals the reservoir exposing the CSS, which seals the micro-chamber therein upon exposure to the liquid (e.g., trapping some of the liquid in the micro-chamber for analysis).

A biopsy device includes a body, a needle, a cutter, a tissue sample holder, and a gate assembly. The needle extends distally from the body. The cutter is longitudinally translatable relative to the needle and defines a cutter lumen. The tissue sample holder is coupled proximally relative to the body. The cutter lumen of the cutter defines at least a portion of a fluid conduit extending between the cutter and the tissue sample holder. The gate assembly is configured to selectively arrest movement of a tissue sample holder within the fluid conduit between the cutter and the tissue sample holder.