The present disclosure relates to the technical field of biomedical materials, more particularly to a degradable magnesium alloy in-situ composite anastomotic staple and a preparation method thereof. The anastomotic staple, with a composite structure, is mainly composed of Mg—Zn—Nd magnesium alloy with high strength and good plasticity (internal part), and corrosion-resistant MgF.sub.2 (external part), and is formed by in-situ synthesis of MgF.sub.2 with the outer layer of Mg—Zn—Nd magnesium alloy anastomotic staple. The magnesium alloy composite anastomotic staple provided by the present disclosure has good plastic deformation ability and mechanical strength, a low degradation rate, and a high biosafety level, which can meet the in-vivo implantation requirements. In addition, it can gradually degrade in vivo after achieving the medical effects in vivo, avoiding a second operation for removal.

A surgical buttress for use in a surgical stapling apparatus is provided and includes an elongate rectangular body portion defining a width; a neck portion integrally formed with and extending from a distal end of the body portion, the neck portion defining a width; a head portion integrally formed with and connected to a distal end of the neck portion, the head portion defining a width; and a tail portion integrally formed with and extending from a proximal end of the body portion, the tail portion defining a width. The width of the tail portion is less than the width of the body portion.

Described herein are polymeric particles configured for intravascular delivery of pharmaceutical agents, e.g., to a diseased site, and methods of forming and using same. Preparation of these polymer particles is also described.

An improved gastroesophageal reflux preventer and related methods are provided. The improved gastroesophageal reflux preventer may include an absorbable material able to be placed in contact with a body organ and configured to induce a scarification of the body organ in response to absorption by the body organ of the material. In this manner, a proximate sphincter may be tightened, such as to ameliorate reflux through a gastroesophageal sphincter.

In general, systems and methods described herein include active or passive sensing mechanisms, such as sensors, that can monitor at least one exposure condition of an adjunct and any medicant(s) retained therein. In some instances, the active or passive sensing mechanisms can also track the extent of the adjunct's and medicant(s)'s exposure, e.g., frequency, intensity, and/or duration).

In general, systems and methods described herein include active or passive sensing mechanisms, such as sensors, that can monitor at least one exposure condition of an adjunct and any medicant(s) retained therein. In some instances, the active or passive sensing mechanisms can also track the extent of the adjunct's and medicant(s)'s exposure, e.g., frequency, intensity, and/or duration).

In general, systems and methods described herein include active or passive sensing mechanisms, such as sensors, that can monitor at least one exposure condition of an adjunct and any medicant(s) retained therein. In some instances, the active or passive sensing mechanisms can also track the extent of the adjunct's and medicant(s)'s exposure, e.g., frequency, intensity, and/or duration).

Compressible adjuncts for use with a staple cartridge are provided. In one exemplary embodiment, the compressible adjunct includes a non-fibrous adjunct material formed of at least one fused bioabsorbable polymer. The adjunct material is configured to be releasably retained on a staple cartridge and is configured to be delivered to tissue by deployment of staples in the cartridge The adjunct material includes a lattice macrostructure having at least one drug contained therein. The lattice macrostructure is formed of a plurality of unit cells, in which each unit cell is configured to eject a predetermined amount of drug from the adjunct material and the predetermined amount of the drug being a function of a compression profile of the respective unit cell.

Systems and methods for forming an anastomosis between two adjacent walls of a digestive tract are provided. The system can include first and second magnetic implants configured to magnetically couple through two adjacent walls of the digestive tract to compress a portion of the two adjacent walls therebetween and form a necrotic area that becomes surrounded by a scarred edge following a healing time period. The magnetic implant can include a magnetic member and a non-magnetic member. The system can include a retention member extending outwardly from a corresponding one of the first and second magnetic implants, the retention member being configured to retain the magnetic implants in position and prevent passage thereof through the necrotic area during the healing time period, and to maintain an engagement between the magnetic member and the non-magnetic member during the healing time period and enable disengagement thereof following the healing time period.

A tether assembly may be attached to a bone to correct a rotational deformity. The bone may have a growth plate that separates a first section of the bone from a second section of the bone. The tether assembly may have a tether member with a first end, a second end, and a central portion extending between the first end and the second end. The first end may have a closed outer wall that defines and fully bounds a first aperture. The second end may have an open outer wall that defines and partially bounds a second aperture. The open outer wall may define a slot in communication with the second aperture. The first and second ends may be securable to the first and second sections of the bone via coupling members inserted through the first and second apertures and anchored in the first and second sections, respectively.