An organ transplant system provides a pumping and refrigeration unit and a sterile disposable set to maintain a desired temperature of an organ during transplantation and to position the organ adjacent a surgical site during an organ transplantation procedure. Handling and exposure of the organ is minimized while maintaining position and condition of the organ.

A device for delivering a bone material to a surgical site is provided. The device comprises a body having an upper portion and a lower portion. The lower portion of the body is substantially transverse to the upper portion and has an opening for receiving a bone material. An internal chamber is disposed within the upper portion and the lower portion, and a plunger is slidably disposed in at least the internal chamber of the body. The plunger has a distal end configured for delivering the bone material out of the lower portion of the body, wherein movement of the plunger in a first position toward the lower portion of the body delivers the bone material from the lower portion of the body to the surgical site. Methods of delivering the bone material are also provided.

Methods of bioprinting a bio-ink construct on an internal tissue defect or a chondral defect during a minimally invasive surgery on an individual in need thereof are provided, comprising: visualizing the defect; positioning a bioprinter comprising a printhead within proximity of or in contact with the defect; and ejecting a bio-ink from the printhead onto the defect to form a bio-ink layer, thereby generating a bio-ink construct. Further provided are systems for bioprinting a bio-ink construct on an internal tissue defect during a minimally invasive surgery on an individual in need thereof, comprising a control system, an endoscope, and a bioprinter comprising a printhead.

According to the present invention, there are provided a chamber for transplantation, as a planar chamber for transplantation which has a structure in which membranes for immunoisolation face each other, and which is capable of stably enclosing a biological constituent, including a membrane for immunoisolation at a boundary between an inside and an outside of the chamber for transplantation, in which the membranes for immunoisolation which face each other have joint portions that are joined to each other, an interior space includes a point at a distance of 10 mm or longer from any position of the joint portion, and the membrane for immunoisolation has flexibility that allows a distance of 1 mm to 13 mm as the following distance: in a case where a portion of 10 mm from a side surface of one short side of a 10 mm×30 mm rectangular test piece of the membrane for immunoisolation is vertically sandwiched between flat plates, and the flat plates are placed horizontally, a distance between a horizontal plane including a center plane in a thickness direction of the sandwiched portion of the membrane for immunoisolation, and a part, which is farthest from the horizontal plane, of a residual 20 mm-portion projecting from the flat plate; and a device for transplantation including the chamber for transplantation enclosing a biological constituent therein.

The present disclosure provides a dual-blade tendon cutting apparatus and cartridge for multiple apparatuses. Exemplary aspects of the present disclosure relate to a cutting implement that comprises two parallel blades that are spaced apart from one another by a predefined distance. The distance between the blades determines a lateral size of a graft being taken from the quadriceps tendon. To simplify matters for the surgeon, a cartridge is provided with three different blade sets. Much like a razor that has a disposable head, the cutting implement may attach to a desired blade set and be used.

Methods for whip-stitching soft tissue with a needle and a looped suture avoid placing the tissue graft through the suture loop, which also eliminates the need for passing a tissue clamp through the suture loop. The methods described herein can also include combinations of the techniques described.

Systems, instruments, and methods are described in which an apparatus comprises a housing including a scalpet device. The scalpet device includes a scalpet array that includes scalpets arranged in a pattern. The scalpets are deployable from the housing to generate incised skin pixels at a target site. The housing is positioned and the scalpet array is deployed into tissue at the target site. Incised skin pixels are generated when the target site is a donor site, and skin defects are generated when the target site is a recipient site. The incised skin pixels are harvested.

A medical device for thermally insulating a graft to be transplanted includes a cover body or receptacle. The cover body includes a cavity within which the graft is received, in use. The cover body is made of a biocompatible thermally insulating material. The cover body has a shape similar to that of the graft. In use, the medical device is configured to keep the graft received therein sufficiently cool to substantially prevent warm ischaemic injury to the graft.

An organ preservation system is provided. The organ preservation system is embodied in a sleeve adapted to maintain a pre-transplant organ at a temperature lower than ambient temperature through a plurality of bladders interconnected by a deformable mesh. With the organ in the sleeve, each vessel of the organ can pass through separate, deformable holes of the mesh, facilitating ease of identification of each vessel needed for the pending vascular anastomosis.

A tissue collection and processing system for collecting bone fragments and tissue aspirated from a bone. The tissue collection and processing system includes a collection vessel, a collection vessel cap, a processing cover, a first tubing and a fluid withdrawal mechanism. The collection vessel has an opening formed therein to receive bone fragments and tissue aspirated from the bone. The collection vessel cap is capable of engaging the collection vessel to substantially seal the opening. The collection vessel cap or the collection vessel has a first port. The processing cover has an upper surface and a lower surface. The processing cover has a connection port and a bore. The connection port is proximate the upper surface. The bore is fluidly connected to the connection port and extends toward the lower surface. The processing cover has a density that is less than a density of fluid in the aspirated bone fragments and tissue. The fluid withdrawal mechanism is fluidly connected to the connection port with the first tubing to withdraw the fluid from the collection vessel. As fluid is withdrawn from the collection vessel, the processing cover is slidable in the collection vessel.