A method is disclosed comprising obtaining or acquiring image or other data from one or more regions of a target using an imaging sensor. The image or other data may then be used to determine one or more regions of interest of the target. An ambient ionisation ion source may then be used to generate aerosol, smoke or vapour from one or more regions of the target.

In combined methods for treating a patient using time-varying magnetic field, treatment methods combine various approaches for aesthetic treatment. A magnetic field generating device is placed proximate to a body region of the patient. The magnetic field generating device generates a time-varying magnetic field with a magnetic flux density in a range of 0.5 to 7 Tesla. The time-varying magnetic field is applied to the body region of the patient in order to cause a contraction of a muscle within the body region. A second therapy may be used by applying one or more of optical waves, radio frequency waves, mechanical waves, negative or positive pressure or heat to the body region of the patient.

Combined methods for treating a patient using time-varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.

A treatment system can include a channel generation system configured to expose an infected region of a target tissue with a laser beam traveling along an optical axis and focused at a focal volume located in or adjacent to the target tissue. The laser beam can have a wavelength ranging from about 100 nm to about 400 nm. The laser beam can be configured to generate at least a first channel in the infected region. The treatment system can also include a detection system configured to detect a first radiation generated by one or more of (i) the target tissue, (ii) a fungi coupled to the infected region in the target tissue, and (iii) an adjacent tissue located proximal to the target tissue as a result of interaction with the laser beam. The treatment system can also include a delivery system configured to deposit an active treatment agent in the at least first channel.

Systems and methods for a laser-assisted topical treatment of nail fungal infections are provided. The laser-assisted topical treatment includes a laser that is configured to output a beam that penetrates the infected nail and creates a channel therethrough. The laser-assisted topical treatment further includes a treatment agent comprising a vehicle and a drug. The treatment agent is applied to an exterior surface of the infected nail so that the treatment agent may flow into the channel.

Methods for treating nerve damage in a muscle, e.g., denervated muscle tissue (e.g., muscle damaged from traumatic injury), in a patient in need thereof featuring performing a pre-operative muscle biopsy on the denervated muscle tissue; making visible motor end plates (MEPs) in neuromuscular junctions (NMJs) in the biopsy; and performing a nerve transfer (e.g., partial radial nerve to axillary transfer) if (i) the MEPs shown in the biopsy persist and (ii) the MEPs shown in the biopsy retain their structures and exhibit certain morphometric properties. The nerve transfer helps regain neuromuscular function of the denervated muscle tissue. The biopsy may feature the use of two-photon microscopy. In certain embodiments, the method is performed at least 6 months after injury to the patient.

In combined methods for treating a patient using time-varying magnetic field, treatment methods combine various approaches for aesthetic treatment. A magnetic field generating device is placed proximate to a body region of the patient. The magnetic field generating device generates a time-varying magnetic field with a magnetic flux density in a range of 0.5 to 7 Tesla. The time-varying magnetic field is applied to the body region of the patient in order to cause a contraction of a muscle within the body region. A second therapy may be used by applying one or more of optical waves, radio frequency waves, mechanical waves, negative or positive pressure or heat to the body region of the patient.

An injectable electrode which is manufactured in the body by curing from a liquid phase to a solid phase, and therefore molding to the contours of the bodily structures where it is injected.

Arthroscopic cutters are used for resecting tissues, such as meniscal tissues, in meniscectomies or other arthroscopic procedures. The arthroscopic cutters have a shaft assembly with openable-closeable jaws at a working end of the shaft. A handpiece having a motor drive may be detachably coupled to a hub on a hub end of the handpiece. When the shaft is coupled to the handpiece, the motor drive will couple to the jaw structure to open and close the jaw structure to cut meniscal and other tissues.

The invention concerns an implementable semiconductor device that includes an electrode configured to be in contact with biological tissue and at least one capacitor, and wherein the capacitor includes a capacitor electrode having a first surface facing and in contact with the electrode configured to be in contact with biological tissue.