A cryoablation catheter, comprising a balloon (1) and a delivery catheter (2) passing through the balloon (1). The delivery catheter (2) is provided with a fluid inflow cavity (21) and a fluid outflow cavity (22) therein. The fluid inflow cavity (21) extends into the balloon (1), and a side wall of the fluid inflow cavity (21) is provided with a spray head (211) that injects a liquid into the balloon (1). The spray head (211) has a number of spray holes (2111, 2112) circumferentially arranged on the exterior of the fluid inflow cavity (21). An end of the fluid outflow cavity (22) has a cross section (24) that seals the fluid outflow cavity (22), and a side wall of the fluid outflow cavity (22) is provided with a reflow hole (221) in communication with the balloon (1). A fluid flows from the fluid inflow cavity (21) through the nozzle holes (2111, 2112) into the balloon (1). The nozzle holes (2111, 2112) are evenly distributed outside the fluid inflow cavity (21), so that the interior of the balloon (1) is uniformly filled with the refrigeration fluid, ensuring the uniformity of heat exchange at each part of the balloon (1) in an axial direction. The fluid then flows out from the reflow hole (221). The structural design can effectively improve the heat exchange efficiency of the fluid, and the production and processing processes are relatively simple.

A cryoablation catheter, comprising a balloon (1) and a delivery catheter (2) passing through the balloon (1). The delivery catheter (2) is provided with a fluid inflow cavity (21) and a fluid outflow cavity (22) therein. The fluid inflow cavity (21) extends into the balloon (1), and a side wall of the fluid inflow cavity (21) is provided with a spray head (211) that injects a liquid into the balloon (1). The spray head (211) has a number of spray holes (2111, 2112) circumferentially arranged on the exterior of the fluid inflow cavity (21). An end of the fluid outflow cavity (22) has a cross section (24) that seals the fluid outflow cavity (22), and a side wall of the fluid outflow cavity (22) is provided with a reflow hole (221) in communication with the balloon (1). A fluid flows from the fluid inflow cavity (21) through the nozzle holes (2111, 2112) into the balloon (1). The nozzle holes (2111, 2112) are evenly distributed outside the fluid inflow cavity (21), so that the interior of the balloon (1) is uniformly filled with the refrigeration fluid, ensuring the uniformity of heat exchange at each part of the balloon (1) in an axial direction. The fluid then flows out from the reflow hole (221). The structural design can effectively improve the heat exchange efficiency of the fluid, and the production and processing processes are relatively simple.

A thermal control unit for controlling a patient's temperature includes a fluid outlet for delivering temperature-controlled fluid to a patient, a pump, a heat exchanger, and a controller that automatically pauses thermal treatment of the patient prior the patient reaching a target temperature. During the pause, the controller assesses a reaction of the patient and changes a temperature of the fluid only inside the thermal control unit if the patient is likely to reach the target temperature without further thermal treatment. However, if the patient is unlikely to reach the target temperature without further thermal treatment, the controller restarts the thermal treatment. The controller may pause thermal treatment again prior to reaching the target temperature and assess the patient's reaction. In some embodiments, the controller may selectively include and exclude a fluid reservoir in a circulation channel within the thermal control unit.

A thermal control unit for controlling a patient's temperature includes a fluid outlet for delivering temperature-controlled fluid to a patient, a pump, a heat exchanger, and a controller that automatically pauses thermal treatment of the patient prior the patient reaching a target temperature. During the pause, the controller assesses a reaction of the patient and changes a temperature of the fluid only inside the thermal control unit if the patient is likely to reach the target temperature without further thermal treatment. However, if the patient is unlikely to reach the target temperature without further thermal treatment, the controller restarts the thermal treatment. The controller may pause thermal treatment again prior to reaching the target temperature and assess the patient's reaction. In some embodiments, the controller may selectively include and exclude a fluid reservoir in a circulation channel within the thermal control unit.

The invention generally relates to systems and methods for therapeutically modulating nerves in or associated with a nasal region of a patient for the treatment of a rhinosinusitis condition.

The invention generally relates to systems and methods for therapeutically modulating nerves in or associated with a nasal region of a patient for the treatment of a rhinosinusitis condition.

The present disclosure provides a device and a method for cooling living tissues for a medical purpose and other purposes. The cooling device comprises: a container configured to accommodate a cooling medium and thermally coupled with the cooling medium by directly contacting the cooling medium; a cooling generator configured to be thermally coupled with the container by a direct contact and thereby to provide cooling energy to the cooling medium; and a heat sink dissipating heat from the cooling generator, the heat sing being configured to be spaced apart from the cooling generator and to be thermally coupled with the cooling generator without a direct contact with the cooling generator.

The present disclosure provides a device and a method for cooling living tissues for a medical purpose and other purposes. The cooling device comprises: a container configured to accommodate a cooling medium and thermally coupled with the cooling medium by directly contacting the cooling medium; a cooling generator configured to be thermally coupled with the container by a direct contact and thereby to provide cooling energy to the cooling medium; and a heat sink dissipating heat from the cooling generator, the heat sing being configured to be spaced apart from the cooling generator and to be thermally coupled with the cooling generator without a direct contact with the cooling generator.

The present invention relates to methods for use in the selective disruption of lipid-rich cells by controlled cooling. The present invention further relates to a device for use in carrying out the methods for selective disruption of lipid-rich cells by controlled cooling.

The present invention relates to methods for use in the selective disruption of lipid-rich cells by controlled cooling. The present invention further relates to a device for use in carrying out the methods for selective disruption of lipid-rich cells by controlled cooling.