There is provided a computerized method of tracking a position of an intra-body catheter, comprising: physically tracking coordinates of the position of a distal portion of a physical catheter within the physical body portion of the patient according to physically applied plurality of electrical fields within the body portion and measurements of the plurality of electrical fields performed by a plurality of physical electrodes at a distal portion of the physical catheter; registering the physically tracked coordinates with simulated coordinates generated according to a simulation of a simulated catheter within a simulation of the body of the patient, to identify differences between physically tracked location coordinates and the simulation coordinates; correcting the physically tracked location coordinates according to the registered simulation coordinates; and providing the corrected physically tracked location coordinates for presentation.

An augmented reality system includes a head-mountable augmented reality platform (152) having a display to provide guidance to a user. A prediction module (115) is trained in a procedure and is configured to predict a next activity in the procedure based on a current condition. An image generation module (148) is responsive to the prediction module to provide a visual cue of a predicted next activity to the user through the head-mountable augmented reality platform.

A system for adjusting an operating state of a medical electronic device is described. In an aspect, the system includes an optical tracking system configured to detect three or more tracking markers. The system also includes a processor coupled with the optical tracking system. The processor is programmed with instructions which, when executed, configure the processor to: configure an input command by assigning at least one operating state of the medical electronic device to a particular state of at least one of the tracking markers; after receiving a priming command, identify a present state of the tracking markers based on data from the optical tracking system; compare the present state with the particular state assigned to the operating state; and based on the comparison, determine that an input command has been received and adjust the operating state of the medical electronic device to the assigned operating state.

A freely-connectable three-strut parallel orthopedic external fixator including two fixation rings and three struts, connecting holes are circumferentially and uniformly distributed on the ring surfaces of each fixation ring, each strut is provided with two driving translational pairs, a revolute pair and a spherical pair. Two fixation rings are respectively fixedly connected with the bone segments of the fracture site by using medical metal bone pins; adjusting the driving translational pairs of the six struts can achieve six DoF relative movement of the two fixation rings, thereby achieving fracture reduction. The external fixator of the present invention realizes free connection between the two fixation rings, which facilitates fixator installment; number of struts is less than the existing external fixators.

The present disclosure relates to compositions and methods of carbonic anhydrase IX inhibitors. The present disclosure also relates to targeting conjugates of carbonic anhydrase IX inhibitors. The present disclosure also relates to the use of targeting conjugates of carbonic anhydrase IX inhibitors in methods of treating disease and for imaging of disease.

A tracker 30 for a Head-Mounted Display, HMD, unit is provided. The tracker 30 comprises a carrier element 10 carrying one or more markers 16a, 16b that are configured to permit determining a position of the tracker 30. The carrier element 10 comprises at least one magnetic element 32 configured to cooperate with at least one magnetic element 22 provided on the HMD unit 62, or on a base element 20 that is to be fixed to the HMD unit 62, for detachably attaching the carrier element 10 to the HMD unit 62.

Systems and methods of tracking a head of a patient are provided. The system includes a motion tracking system and a head tracker. The head tracker includes a frame, at least one trackable target coupled to the frame, at least one nose pad coupled to the frame, and a pair of adjustable ear coupling members coupled to the frame and shaped for engaging with at least a portion of a back surface of an ear of the patient. The head tracker is configured to apply a clamping force to hold the trackable target in a stable spatial relationship with a location of interest in the head. The motion tracking system includes a sensor for tracking the trackable target and a processor configured for determining a position of the location of interest from the position and orientation of the trackable target and the stable spatial relationship.

An imaging system aka 3d camera operative in conjunction with a tube having two open ends, the system comprising active portions small enough to fit into the tube and an electronic subsystem including a hardware processor operative to receive image/s from the active portions and to generate therefrom at least one 3D image of a scene visible via one of the tube's open ends. The system may comprise a tracker configured to be secured to the tube, and a method for monitoring location, e.g. absolute location, of the tube, accordingly.

A coupling system for securing and positioning a reflective marker in a navigation array is disclosed. The coupling system can include a carrier configured to hold the marker with a reflective element for detection by a surgical tracking system in a socket of the array. The carrier can include a body with an exterior for interfacing with the socket and an open end with engagement features for holding a body of the marker. The carrier is configured to visibly present the reflective element of the marker in the socket when the carrier is disposed in the socket. The carrier can be configured to securely hold the marker to the array when the marker is disposed in the carrier and the carrier is disposed in the array such that the marker cannot be removed from the carrier unless the carrier is removed from the socket.

A medical tube or cannula comprising enhanced imaging structure and/or materials is provided. In some embodiments, an otherwise solid echogenic band may be interrupted by echolucent features and/or materials. In other embodiments, an echogenic band may be adjacent to an echolucent band, while in other embodiments one or more echolucent bands may be provided. In some cases, two or more spaced-apart echolucent bands may be provided. In some embodiments, an echolucent band may comprise an echogenic feature or materials. Generally, the juxtaposition of echogenic and echolucent materials enhances the imaging contrast of an intravascular device and allows easy identification and positioning of the juxtaposed echogenic and echolucent regions.