The invention relates to a sealing device for repair of cardiac and vascular defects or tissue opening such as a patent foramen ovale (PFO) or shunt in the heart, the vascular system, etc. and particularly provides an occluder device and trans-catheter occluder delivery system. The sealing device would have improved conformity to heart anatomy and be easily deployed, repositioned, and retrieved at the opening site.

A method for calculating during use the geometric parameters of an x-ray imaging system, an object or a patient to be observed being placed between the x-ray source and a detector of x-rays having passed through the object or patient, wherein it includes at least the following steps: detecting at least one marker on the object or the patient or in proximity to the object, the marker being of unknown 3D position, acquiring a plurality of 2D images for a plurality of viewpoints of the imaging system, detecting the position of at least one marker in each of the acquired 2D images, estimating the projection matrices corresponding to the projections of the object at various viewing angles and reconstructing in 3D the position of a marker on the basis of the estimation of the projection matrices.

A method and system for facilitating identification and marking of a target in a displayed Fluoroscopic Three-Dimensional Reconstruction (F3DR) of a body region of a patient. The system includes a display and a storage device storing instructions for receiving an initial selection of the target in the F3DR, fining the F3DR based on the initial selection of the target, displaying the fined F3DR on the display, and receiving a final selection of the target in the fined F3DR via a user selection. The system further includes at least one hardware processor configured to execute said instructions. The method and instructions may also include receiving a selection of a medical device in two two-dimensional fluoroscopic images, where the medical device is located in an area of the target, and initially fining the F3DR based on the selection of the medical device.

A registration fixture or plate is configured for use with a medical imaging system. The registration fixture may be an optical magnetic registration plate including a plurality of fiducial markers in arranged in a predefined unique pattern. The pattern can be unambiguously detected on 2D image of the plate produced by the medical imaging system. Association of the 2D imaged pattern of fiducial markers with the actual 3D pattern on the optical magnetic registration plate allows for accurate calculation of projection matrices and co-registration of the 3D and 2D coordinate systems.

Examples of systems and methods described herein may utilize augmented reality devices and pointers in generating intra-operative plans and providing guidance for knee surgery. A pointer may indicate one or more anatomical points. An augmented reality device may detect positions of knee anatomical features based on a position of the pointer and positions of fiducials associated with a marker affixed to body part proximate to a knee, such as a femur or a tibia. The augmented reality device may generate a planned resection plane based on the positions of the knee anatomical features, and determine an actual resection plane based on a view of a resection guide having a marker inserted in the guide. The augmented reality device may provide guidance to position the guide to align the actual resection plane with the planned resection plane.

An apparatus is provided that is visible by both a three dimensional (3D) scanner system of a medical navigation system and a camera of the medical navigation system. The apparatus involves a rigid member and a plurality of markers attached to the rigid member. Each of the plurality of markers includes a reflective surface portion visible by the camera and a distinct identifiable portion visible by the 3D scanner system. The apparatus further involves a connector mechanism to connect the apparatus to a reference location. The apparatus is in a field of view of the 3D scanner system and the camera within a timeframe of the 3D scan.

A system and method for estimating a pose of an imaging device for one or more images is provided.

Systems and methods for marking the location and extent of an anatomical region-of-interest, such as a tumor, using magnetic seeds whose position and orientation are measured or otherwise detected using a detection device that includes two or more magnetic sensors are described. One or more magnetic seeds are implanted to mark and define the center and extent of an anatomical region-of-interest and a magnetic sensor-based detector system is used to accurately identify the location of the magnetic seeds.

A head stabilization device or HFD includes a plurality of integrated markers. The HFD may be in the form of a skull clamp, vacuum bag, combinations thereof, or other supporting structure. The integrated markers include MRI markers detectable by an MRI scanner and fiducial markers detectable by a registration tool of a navigation system. The markers provide a reference point relative to an operation site in a patient for use in a navigation guided procedure and aid in registering or calibrating the location of the patient with captured images used in the navigation guided procedure.