An apparatus to treat a patient, the apparatus comprises a carrier having a proximal end and a distal end, an optical fiber to couple to a light source, a fluid delivery element comprising a nozzle having an orifice on the distal end, and an alignment structure to align the optical fiber with the orifice. A distance extends between the alignment structure and the orifice, such that the light beam emitted from the optical fiber diverges so as to allow energy transmission and fluid flow through the orifice. In some embodiments, the apparatus to ablate tissue comprises a source of pressurized fluid, and the nozzle is coupled to the source of pressurized fluid to release a fluid stream.

A system for working biological tissue, the system comprising: a tool comprising a laser operable to perform at least one action of work; positioning means for positioning the tool relative to the biological tissue to perform the at least one action of work; a controller; storage storing electronic program instructions for controlling the controller; and an input means; wherein the controller is operable, under control of the electronic program instructions, to: receive input via the input means; process the input and, on the basis of the processing, control the positioning means and the tool to work the biological tissue.

A gas removal apparatus and a method for removing gas bubbles from at least a part of a medical device disposed in an interior chamber of a gas removal apparatus. The gas removal apparatus includes an interior chamber, a filling surface, a first opening arranged at an end of the filling surface and that provides a first path into the interior chamber, and a second opening that provides a second path into the interior chamber. When the apparatus is arranged in a liquid receiving position, at least a portion of the at least the part of the medical device is disposed above an uppermost surface of liquid in the interior chamber, and when the apparatus is arranged in another position different from the liquid receiving position, the entirety of the at least the part of the medical device is disposed below an uppermost surface of liquid in the interior chamber.

An electrosurgical device comprises an electrically conductive elongate member for traversing body vasculature defining a hollow lumen with one or more apertures at or near its distal end, wherein electrical energy can flow through the wall of the elongate member; and an energy delivery device in electrical communication with the elongate member is located distal to the end of the elongate member. The energy delivery device includes an electrode for delivering energy. Methods of using the electrosurgical device include cutting through occlusions and creating transseptal punctures.

The invention provides an apparatus for the generation and administration of a micro-nanobubble solution to a tissue, a method for the treatment of a tissue with a solution of micro-nanobubbles, and a kit for the treatment of tissue with micro-nanobubbles.

A surgical system includes an ultrasonic generator configured to provide an ultrasonic drive signal, an ultrasonic transducer coupled to the ultrasonic generator to receive the drive signal and produce mechanical ultrasonic energy, an electrosurgical generator configured to output three-phase RF energy, and an end effector assembly. The end effector assembly includes an ultrasonic blade coupled to the transducer to supply the mechanical ultrasonic energy to tissue to treat tissue. At least a portion of the ultrasonic blade defines a first electrode; second and third electrodes are also provided. The first and second electrodes, the first and third electrodes, and the second and third electrodes are electrically coupled to the electrosurgical generator and configured to conduct the first, second, and third phases, respectively, of the three-phase RF energy therebetween and through tissue to at least one of treat or interrogate tissue.

Provided herein are expandable devices, rail systems, and motorized devices. In one embodiment, an expandable device comprises an expandable sac having a tool housed therein. The expandable device is optionally configured for operation while inside a body cavity. The expandable device optionally comprises at least one rail in the sac, and at least one railed device coupled to the rail for movement there on. Movement of the railed device on the rail is provided by, for example, a motor such as an electromagnetic motor or an inch-worm type motor. Expandable devices can be used, for example, to perform minimally invasive medical procedures requiring access to a body cavity. Expandable devices can also be used, for example, to provide safe and stable transport of instruments to the body cavity.

A medical tubing member is used in a medical system that allows fluid to flow between an inside and outside of a subject. The medical tubing member includes a first tubing member and a second tubing member. The first tubing member is configured to be arranged outside the subject and is configured to be connected to a first line disposed in an endoscope. The first tubing member is configured to supply the fluid from the outside of the subject to the inside of the subject. The second tubing member is configured to be arranged outside the subject and configured to be connected to a second tubular line disposed in the endoscope. The second tubing member is configured to discharge the fluid from the inside of the subject to the outside of the subject. The second tubing member is disposed inside the first tubing member.

An instrument includes an ultrasonic blade, a first fluid port, an irrigation member, a second fluid port, and a fluid communication assembly. The ultrasonic blade defines a distal opening. The ultrasonic blade is operable in a first mode to emulsify tissue that is distally positioned relative to the ultrasonic blade. The ultrasonic blade is further operable in a second mode to transect and seal tissue that is transversely positioned relative to the ultrasonic blade. The first fluid port is in communication with the distal opening of the ultrasonic blade. The irrigation member is positioned adjacent to the distal end of the ultrasonic blade. The second fluid port is in communication with the irrigation member. The fluid communication assembly is configured to couple the first fluid port with a fluid source, couple the first fluid port with a suction source, and couple the second fluid port with the fluid source.

An endoscopic surgical instrument includes at least one endoscopy shaft, with at least one suction and/or rinse unit, with at least one securing element, which is configured to secure the at least one endoscopy shaft on the at least one suction and/or rinse unit in a coupled state, and with at least one fixation unit, which is configured for a captive fixation of the at least one securing element on the at least one suction and/or rinse unit, wherein the at least one fixation unit comprises at least one cover element which, in a mounted state, encompasses the at least one securing element at least partly, wherein the at least one cover element comprises at least one operational recess for an operation of the at least one securing element.