A method of fetal ultrasound monitoring includes detecting contact of a first ultrasound transducer to a mother’s abdomen based on input from a contact sensor in the first ultrasound transducer. A first transducer identifier is received from the first ultrasound transducer, and then the first transducer identifier is correlated with a first transducer label. A first heart rate is measured based on output of an ultrasound device in the first ultrasound transducer, and a heart rate indicator is displayed accordingly. A position of the first ultrasound transducer is identified in a two-dimensional plane, and the first transducer label is displayed on an abdomen image based on the first position.

A multi-sensor patch for simultaneous abdominal monitoring of maternal and fetal physiological data includes a multi-layer flexible substrate. The multi-layer flexible substrate includes a center region and a plurality of electrode regions. An electrode of the plurality of electrodes is located in each of the electrode regions. At least one auxiliary sensor which may be an optical sensor. A module unit is connected to the conductive layer at the center region. The module unit is configured to receive biopotential physiological data from the plurality of electrodes and photosignal data from the optical sensor. The module unit calculates at least fetal heart rate (fHR), maternal heart rate (mHR), and uterine activity (UA) from the biopotential physiological data and fHR, mHR, and SpO2 from the photosignal data.

The present invention relates to a transfer assembly for transferring a preterm baby from a natural womb of a pregnant mammal to a transfer bag, comprising abase device having a pass-through opening configured to allow the preterm baby to pass through the base device, and wherein the base device is connected to a birth canal retractor, said birth canal retractor comprises a flexible sleeve disposed between the base device and an adjustable access ring, which retractor is to be inserted into the birth canal of the pregnant mammal at least with the access ring thereof, and wherein the access ring is configured to be expanded or inflated while in the birth canal, wherein the assembly further comprising a transfer device comprising the transfer bag, said transfer bag being a flexible bag provided with an opening configured to allow the preterm baby to be received in the transfer bag, and wherein the opening is further provided with a coupling member, which coupling member is releasably secured to the base device, and wherein the transfer bag is provided with at least one integrated glove for receiving the hand of a medical practitioner in order to allow the transfer the preterm baby from the natural womb into the transfer bag.

A method of sensing the heart rate and blood oxygen saturation of a maternal patient and a fetal patient can include obtaining maternal electrocardiogram (mECG) data and fetal electrocardiogram (fECG) data with a plurality of electrodes. The method can also include obtaining photosignal data with an optical sensor, the photosignal data including a maternal photosignal component and a fetal photosignal component. Additionally, the method can include applying mECG to the photosignal data to calculate maternal photoplesthograph (mPPG) data, applying the mPPG to the photosignal data to remove the maternal photosignal component from the photosignal data, and applying the fECG to remaining photosignal data to calculate fetal photoplesthograph (fPPG) data.

The disclosed apparatus, systems and methods relate to tracking abdominal orientation and activity for purposes of preventing or treating conditions of pregnancy, respiratory diseases or other types of medical conditions. In certain specific embodiments, the system, device, or method relates to identifying abdominal or sleep position orientation risk values, calculating and updating a cumulative risk value, comparing the cumulative risk value to a threshold, and outputting a warning when the cumulative risk value crosses the threshold.

Methods and apparatus for reducing the risk of neurological injury to a human fetus during labor and before are disclosed, which include the steps of: (1) identifying during labor the risk of neurological injury to a fetus by, conducting an analysis of fetal blood to determine at least a first base excess (BE) value for the fetus; (2) determining a multiple of the median for the BE value at the first period in time, wherein a risk of neurological injury to the fetus is indicated when the BE value is a predefined multiple of a median BE value; and (3) treating the fetus for which the risk of neurological injury is, by intervening in labor to reduce or eliminate the risk of neurological injury to the fetus through any conventional therapeutic measures.

A system and method is provided for monitoring the fetal position and/or orientation of the fetus of an expectant mother. An acoustic sensor array is positioned over the belly. The pattern of acoustic sensor signals is processed to determine a fetal orientation and/or to determine movement over time of the fetus.

A risk stratification method for a patient in a disease state and specifically patients presenting a tumor, includes determining if the patient is a homozygote or heterozygote and further determining the allelic expression for the patient, CC, T/C, or C/T. For patients having the cytosine methylated, they have a C/T allelic expression and patients without a methylated cytosine have a T/C allelic expression. A patient with a TT allelic expression is classified as a highest risk patient, a patient with a T/C allelic expression is classified as a second highest risk patient, a patient with a C/T allelic expression is classified as a third highest risk patient and a patient with a CC allelic expression is classified as a lowest risk patient. The risk stratification method may further include identification of an abnormal expression or mutation/function of a gene product produced by CTCF binding site 6.

The present disclosure describes imaging systems configured to generate volumetric images of a target feature based on anatomical landmarks identified during an ultrasound scan and in accordance with a user-selected view. Systems can include an ultrasound transducer configured to acquire echo signals responsive to ultrasound pulses transmitted toward a target region. A processor coupled with the transducer may present illustrative volumetric images of the target feature, each image corresponding to a particular view, for a user to select. The processor can then identify anatomical landmarks corresponding to the target feature embodied within 2D image frames, and based on the identified landmarks and user-selected view, provide instructions for manipulating the transducer to a target local to generate a 2D image frame specific to the view. Echo signals are then acquired at the target locale and used to generate an actual volumetric image of the target feature corresponding to the user-selected view.

A method for detecting fetal blood oxygen saturation, including: using at least two detection light of different wavelengths, to irradiate a fetus in an examined pregnant woman's abdomen in a time-sharing manner and acquiring first photoplethysmography signals corresponding to the abdomen under irradiation of the respective wavelengths of detection light, and to irradiate a detection site except the examined pregnant woman's abdomen in a time-sharing manner and acquiring second photoplethysmography signals corresponding to the detection site under irradiation of the respective wavelengths of the detection light; determining a target photoplethysmography signal of the fetus that corresponds to the detection light of each wavelength, according to the first photoplethysmography signals and the second photoplethysmography signals that correspond to the detection light of each wavelength; and determining the fetal blood oxygen saturation, according to respective target photoplethysmography signals determined.