Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.

Disclosed herein are apparatuses for manipulation of an ear device within the ear canal of a subject. Also disclosed herein are methods of using said apparatuses for the insertion, removal, or other manipulations of the ear device. Also disclosed herein are methods of making the apparatuses, and kits containing the apparatus with instructions for use.

Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3D) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3D video data itself—rather than using a priori definitions for what should constitute a measurable unit of action—identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action. The systems and methods of the invention can be applied to drug or gene therapy classification, drug or gene therapy screening, disease study including early detection of the onset of a disease, toxicology research, side-effect study, learning and memory process study, anxiety study, and analysis in consumer behavior.

A veterinary vital signs monitoring system, including: (A) two stretchable bands, each having an electrically conductive component; (B) a housing including two fasteners with electrically conductive contacts, each fastener adapted to receive, and lock therein a portion of one of the bands, the conductive contacts adapted to make an electrical connection with electrically conductive components of the bands; and (C) a module housed in the housing and in electrical communication with the conductive contacts, the monitoring module adapted to receive signals relating to vital signs of the animal on which the bands are mounted, via the conductive components thereof.

The invention provides a sensing system for determining a parameter of a set of animals present on a surface area, wherein the sensing system comprises: a controller; at least one range sensor having a Field-of-View to the surface area; wherein the at least one range sensor is configured to at least continually measure heights of animals of the set of animals passing the Field-of-View during a period of time, and to provide a height signal comprising said measured heights during the period of time; wherein the controller is configured to obtain said height signal, and to determine the parameter of the set of animals based on the measured heights during the period of time.

Disclosed herein are apparatuses for manipulation of an ear device within the ear canal of a subject. Also disclosed herein are methods of using said apparatuses for the insertion, removal, or other manipulations of the ear device. Also disclosed herein are methods of making the apparatuses, and kits containing the apparatus with instructions for use.

A health management system includes a risk calculator 301 for receiving input of vital data on a human or an animal, and for calculating a disease occurrence risk in the human or the animal; and a reduction measure specifier 302 for specifying a reduction measure for reducing the disease occurrence risk in the human or the animal.

A CPU of a health management apparatus functions as an acquisition unit, a first derivation unit, and a screen output control unit. The acquisition unit acquires a body-fat percentage which is an obesity parameter indicating the degree of obesity of a target pet and bone density which is a bone parameter indicating the degree of bone strength of the target pet. The first derivation unit derives health conditions of the target pet on the basis of a correlation between the body-fat percentage and the bone density. A screen output control unit performs control to output a medical examination result display screen on which the health conditions are displayed.

A method for analyzing an acoustic signal having a time period and having a plurality of repeated audio patterns, has the following steps: receiving an audio signal having the acoustic signal; determining the audio patterns repeated within the acoustic signal; determining a window length for a plurality of windows, wherein the window length divides the time period of the acoustic signal into the plurality of windows; and windowing the acoustic signal to obtain the plurality of windows.

The current invention relates to the use of a neural network to improve the quality of images obtained from light scattered by an intermediate object that scatters light, such as tissue or a frosted screen. The invention relates to a method of imaging a human or animal bode using a nanocrystal array capable of fluorescing upon excitation from light from a near-infrared light source. This invention also relates to detection means and apparatus used in said methods, as well as to quantum dots useful in said use.