An aerosol dispenser, outer container for an aerosol dispenser and a preform for an outer container, each include an open neck at the top and a closed end bottom. The open neck may include a first surface having a first surface diameter, a second surface disposed interior to the first surface and having a second surface diameter less than the first surface diameter, and a transition distinguishing the first surface from the second surface. For a dispenser and a container, a product delivery device may be disposed on the second surface and not interfere with a valve operable by a user when the valve is attached to the open neck in engagement with the first surface. At least one of the first and the second surfaces may be a sealing surface to prevent escape of propellant from the outer container to ambient when a valve is attached.

A pressurized dispensing system including a plastic bottle and a method of minimizing the formation of stress cracks in a plastic bottle that is a part of a pressurized dispensing system. In a method of manufacturing the pressurized dispensing system, a plastic bottle is filled with a liquid, a valve is crimped onto the plastic bottle, and the plastic bottle is filled with gas so as to pressurize the plastic bottle. The plastic bottle is supported only in the finish region throughout the liquid filling, valve crimping, and gas filling steps. The filled and pressurized plastic bottle is substantially free of stress cracks.

A method and apparatus of making an aerosol container. A polymeric container may be provided. The container may have a closed end bottom and a neck longitudinally opposed to the closed end bottom. The container has an internal container volume. A valve and a bag may be provided and a portion of the valve and the bag may be disposed within the container. The bag has a first bag volume. A portion of the at least one of the neck and the bag may contact a portion of the valve to form a temporary seal. Propellant may be introduced into the container. The bag may be collapsed from the first bag volume to a second bag volume. The pressure of the propellant and the pressure within the bag equilibrate. The valve may be joined to the container and the propellant may be sealed within the container.

An aerosol dispenser, an outer container for an aerosol dispenser and a preform for an outer container. The aerosol dispenser, outer container and preform each have a neck, which in turn has a crimp ring, to receive a valve cup clinched thereto. The crimp ring has slots which act as vents therethrough. The vents may be exposed to pressurized propellant and product due to deformation of the neck during undue internal pressurization. The cross section of the vents diverge in the downward direction to provide both flow area and for product and propellant and adequate area for the valve cup to be corrugatedly clinched to the crimp ring.

The invention comprises a container apparatus and/or a method of manufacture thereof, comprising: a pressure containment housing containing both a first chemical and a second chemical; an interface configured to control dispersal of the first and second chemical out of the container; and a pressure within the container at time of manufacture exceeding ten bar. Generally, the mixture includes: (1) nitrous oxide as a gas, a liquid, a supercritical fluid, or a solid and (2) at least one of molecular hydrogen, helium, molecular nitrogen, carbon dioxide, neon, argon, krypton, and xenon in the form of a gas, liquid, supercritical fluid, or solid.

The invention comprises a container apparatus and/or a method of manufacture thereof, comprising: a pressure containment housing containing both a first chemical and a second chemical; an interface configured to control dispersal of the first and second chemical out of the container; and a pressure within the container at time of manufacture exceeding ten bar. Generally, the mixture includes: (1) nitrous oxide as a gas, a liquid, a supercritical fluid, or a solid and (2) at least one of molecular hydrogen, helium, molecular nitrogen, carbon dioxide, neon, argon, krypton, and xenon in the form of a gas, liquid, supercritical fluid, or solid.

An assembling apparatus efficiently performs a recovery operation and a parts size change operation. A filling line (the assembling apparatus) has parts supply units that supply parts, assembling units that mount one of the parts to another part, and a conveying unit that individually moves carriers 12 capable of storing parts constituting an assembly. The parts supply units are provided at positions away from the assembling units, the assembling units are accommodated in an isolator having an interior maintained in an aseptic state, and gloves to perform an operation on the assembling units are provided on a side surface of the isolator. The supply units store the parts in one of the carriers, the carrier then moves into the isolator, and the assembling units take the part from the carrier, and mounts the part to the other part stored in the same carrier.

The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.

A unit for mixing and dispensing an aerosol precursor composition, and containers to be dispensed therefrom. The unit includes a plurality of bulk material filling stations, the plurality of bulk material filling stations have at least one first filling station with aerosol former and at least one second filling station with a flavor material for creating the aerosol precursor. The unit also includes a bulk consumable pack staging a plurality of containers configured to receive the aerosol precursor, and a robot configured to retrieve a container from the bulk consumable pack and move the container through at least two dimensions to stop at at least two of the plurality of bulk material filling stations.

The present disclosure is related to a method and product of preparing an anti-agglomeration yogurt-based product for use in an aerosol container, comprising: creating a suspension comprised of at least one dairy ingredient and water, pasteurizing the suspension, cooling the suspension to a temperature range to enable culture activity, inoculating the suspension with a culture of yogurt-forming bacteria, homogenizing the suspension, and packaging the suspension.