According to an example aspect of the present invention, there is provided a box-shaped package, comprising: a base, and a cover configured to be placed on the base to close the package, wherein in a closed configuration of the package, the interface between the base and the cover is gas-tight; the base and/or the cover comprise one or more gas-permeable zones which are capable of passing gases, such as air, into and out from the package, particularly in the closed configuration.

A packaging for sterile packaging application includes: a single layer nonwoven fabric obtained from a nonwoven, the nonwoven including meltblown polymer fibers having an average fiber diameter between 2 μm to 10 μm and a standard deviation of the fiber diameter of at least 100%. The nonwoven is thermally bonded.

A packaging for sterile packaging application includes: a single layer nonwoven fabric obtained from a nonwoven, the nonwoven including meltblown polymer fibers having an average fiber diameter between 2 μm to 10 μm and a standard deviation of the fiber diameter of at least 100%. The nonwoven is thermally bonded.

A medical dispensing system with dispensing and pathway components, each of which of a plurality of dispensers and pathways, respectively. The dispensing and pathway components are controlled to minimize contamination between the items being dispensed. Both the dispensing and pathway components have arcs around which the dispensers and pathways are arranged.

There is disclosed an acellular dermal matrix (ADM) graft stored as a packaged ADM graft pocket product prepared by a process that includes providing a portion of ADM tissue having a thickness between 1 mm and 2 mm. The process includes scoring the portion of the ADM tissue into a pre-defined shape to form the domed shape ADM graft. The process includes verifying the thickness of the domed shape ADM graft; shaping the domed shape ADM graft to form an ADM graft pocket configured to receive a breast implant. The process includes packaging the ADM graft pocket to form a packaged ADM graft pocket. The process includes irradiating the packaged ADM graft pocket to a sterility assurance level of a desired level to form the packaged ADM graft pocket product. Other embodiments are also disclosed.

There is disclosed an acellular dermal matrix (ADM) graft stored as a packaged ADM graft pocket product prepared by a process that includes providing a portion of ADM tissue having a thickness between 1 mm and 2 mm. The process includes scoring the portion of the ADM tissue into a pre-defined shape to form the domed shape ADM graft. The process includes verifying the thickness of the domed shape ADM graft; shaping the domed shape ADM graft to form an ADM graft pocket configured to receive a breast implant. The process includes packaging the ADM graft pocket to form a packaged ADM graft pocket. The process includes irradiating the packaged ADM graft pocket to a sterility assurance level of a desired level to form the packaged ADM graft pocket product. Other embodiments are also disclosed.

Provided is a novel container sterilization method in which no liquid agent is used. A container sterilization method is a method of performing sterilization by supplying a sterilization component to a container that is continuously conveyed along a predetermined conveyance path, the container sterilization method including supplying a humid ozone gas to a sterilization area, the humid ozone gas being an ozone gas that has humidity, the sterilization area being partitioned by a sterilization chamber that contains the conveyance path. The humidity of the humid ozone gas to be supplied to the sterilization region is regulated, depending on a temperature of the containers to be conveyed to the sterilization region.

A packaging machine configured to form, fill, and seal individual packages is provided. The packaging machine includes a disinfection/sterilization station configured to treat ready-to-fill packaging containers passing through said disinfection station. The disinfection/sterilization station includes a supply section configured to provide gaseous sterilizing agent into open ends of the ready-to-fill packaging containers passing the supply section, and a holding section arranged downstream the supply section. The packaging machine is configured to keep the ready-to-fill packaging containers at the supply section such that the sterilizing agent will condense on areas of the ready-to-fill packaging container having a temperature below the dew point of the sterilizing agent, and the packaging machine is configured to keep the ready-to-fill packaging containers at the holding section such that the gaseous sterilizing agent will treat areas of the ready-to-fill packaging container having a temperature above the dew point of the sterilizing agent.

A sterilization method includes a circulation step of circulating a sterilizer through a circulation line (53) while the sterilizer is being heated by a heater (H), and a sterilization step of sterilizing a filling chamber (42) by supplying, to the filling chamber (42), the sterilizer heated by the heater (H).

A sterilization method includes a circulation step of circulating a sterilizer through a circulation line (53) while the sterilizer is being heated by a heater (H), and a sterilization step of sterilizing a filling chamber (42) by supplying, to the filling chamber (42), the sterilizer heated by the heater (H).