A diaphragm-based sensor includes a deflectable diaphragm, a base layer opposite the diaphragm, and a corrugated wall extending between the diaphragm and the base layer. The diaphragm is suspended over a cavity enclosed by the diaphragm, the base layer and the corrugated wall. The diaphragm includes a first electrode and the base layer includes a second electrode such that a capacitance between the first and second electrodes changes when the diaphragm is deflected relative to the cavity.

Conformable and wearable sensors with integrated on-chip gate for the detection of biomolecules, chemicals, and other substrates and applications thereof are provided. Biosensor chips can be built with In2O3 nanoribbon field-effect transistors. Biosensor chips can conform to features of a human body, enabling ability for individuals to wear a biosensor.

Described herein is a catheter and method for catheter assembly. The flexible substrate includes a number of layers, where each layer has a number of printed wires. The printed substrate is environmentally protected. The printed substrate is rolled and inserted into the catheter. Connectors are attached to each end of the rolled substrate. The connectors are connected to sensors at a distal end of the catheter and with electrical cards or a cable connector at a proximate end of the catheter. At least one layer of the substrate is connected to a coil in a magnetic sensor. A layer in which the traces are shorted in the distal end is used to measure a magnetic interference. These measurements are used by a processor or hardware to cancel out the magnetic interference effect on the other layers. In an implementation, another printed substrate can be wrapped within the catheter shaft and used for non-magnetic type sensors.

An implantable medical device includes a header configured to be mounted to an end of a device housing that contains an electronics module therein. The header includes an antenna, a sensing electrode, and a header body that at least partially surrounds the antenna and the sensing electrode. The sensing electrode includes a first body portion, a second body portion, and a bridge portion that mechanically and electrically connects the first and second body portions. The first body portion is at least partially exposed to an external environment along a first side of the header, and the second body portion is at least partially exposed to the external environment along a second side of the header that is different from the first side.

A method of selecting or generating a design for a component of a patient interface device, the method including receiving a scan of at least a portion of a patient's face, receiving preference information about the patient, and generating a custom design or selecting a preexisting design for the component of the patient interface device based on the scan of at least a portion of the patient's face and the preference information, wherein a size or shape of the generated custom design for the component or selected preexisting design for the component is based on the preference information.

Poroelastic materials, methods of making such materials, biosensors comprising such materials, and methods of making and using such biosensors. According to one aspect, a poroelastic material is formed by a process that includes depositing a prepolymer composition on a substrate, annealing the prepolymer composition in a pressurized steam environment at a temperature and for a duration sufficient to form a porous medium having a solid matrix formed of a polymer derived from the prepolymer composition, infiltrating the porous medium with a liquid that includes electrically conductive nanomaterials such that the electrically conductive nanomaterials are located within pores of the porous medium, and evaporating the liquid such that the electrically conductive nanomaterials remain in and/or connected through the pores of the porous medium.

The embodiments disclose a method including providing impedimetric biosensor electrodes and circuits on a substrate, providing at least two different biopolymer materials on the conductive impedimetric biosensors electrodes and circuits, applying a predetermined electrical current to the impedimetric biosensor electrodes for establishing a baseline value, providing at least one biologic sample onto the impedimetric biosensors electrodes for detection of at least one disease microorganism, measuring the electrical current after contact with the at least one biologic sample for changes in the baseline value, recording changes in the electrical current measurements, analyzing the electrical current measurements for identifying predetermined detected disease microorganisms electrical current measurements changes, and determining the concentration of a detected disease microorganism.

Various embodiments of a die carrier package and a method of forming such package are disclosed. The package includes one or more dies disposed within a cavity of a carrier substrate, where a first die contact of one or more of the dies is electrically connected to a first die pad disposed on a recessed surface of the cavity, and a second die contact of one or more of the dies is electrically connected to a second die pad also disposed on the recessed surface. The first and second die pads are electrically connected to first and second package contacts respectively. The first and second package contacts are disposed on a first major surface of the carrier substrate adjacent the cavity.

A biological-electrode protection module is a monolithic component including a capacitor and a voltage-limiting component integrated in a common substrate. The capacitor component is connected in the series path between the input and output terminals. The voltage-limiting component is connected between ground and a node in the series path. The voltage-limiting component has a low breakdown voltage no greater than 6 volts and may be a biphasic device operating in the punch-through mode. Moreover, the protection module is connected to or integrated with a set of biological electrodes at a distance no greater than 1 cm. The capacitor may be a 3D capacitor, and common fabrication processes may be used in forming the voltage-limiting component and the capacitor. A JFET may be integrated in the same substrate so that an electrical signal output from the monolithic protection device is already pre-amplified.

This catheter has: a shaft (2) that has a first end and a second end in the longitudinal direction thereof, has a lumen (3) extending in the longitudinal direction, and has formed therein a side hole (4) being in communication with the lumen (3); a protective tube (10) that is inserted in the side hole (4); a first electrode (20) that is disposed outside the shaft (2); and a wire (30) that is electrically connected to the first electrode (20), passes through the inside of the protective tube (10), and extends into the lumen (3) of the shaft (2).