Described herein is an implantable device configured to detect impedance characteristic of a tissue. In certain exemplary devices, the implantable device comprises (a) an ultrasonic transducer configured to emit an ultrasonic backscatter encoding information relating to an impedance characteristic of a tissue based on a modulated current flowing through the ultrasonic transducer; (b) an integrated circuit comprising (i) a variable frequency power supply electrically connected to a first electrode and a second electrode; (ii) a signal detector configured to detect an impedance, voltage, or current in a circuit comprising the variable frequency power supply, the first electrode, the second electrode, and the tissue; and (iii) a modulation circuit configured to modulate the current flowing through the ultrasonic transducer based on the detected impedance, voltage, or current; and the first electrode and the second electrode configured to be implanted into the tissue in electrical connection with each other through the tissue. Further described are systems including one or more implantable devices and an interrogator for operating the implantable device, methods of measuring impedance characteristic of a tissue in a subject, and methods of monitoring or characterizing a tissue in a subject.

Systems, devices and methods allow inductive recharging of a power source located within or coupled to an implantable medical device (IMD) while the device is implanted in a patient. The IMD may include a rechargeable battery having a battery housing; a non-metallic substrate attached to the battery housing, wherein the non-metallic substrate and the battery housing form an outer housing of the implantable medical device; control circuitry formed on the non-metallic substrate within the outer housing of the IMD; a receive coil within the outer housing of the IMD, the receive coil configured to receive energy from outside of the outer housing of the IMD; and recharge circuitry within the outer housing of the IMD and coupled to the receive coil, the recharge circuitry configured to receive the energy from the receive coil, and recharge the rechargeable battery using the received energy.

A blood pressure measurement cuff is a blood pressure measurement cuff to be attached such that it wraps around a measurement site and includes: a curler that is flexible and curves so as to naturally conform to the measurement site; an air bladder containing the curler due to being wrapped around the inner side and outer side of the curler; an inner cloth attached to an outer surface on the measurement site side of the air bladder; and an outer cloth attached to an outer surface on the side opposite to the measurement site of the air bladder.

There is described a method of producing a flexible structure and sensor devices incorporating the former, such as wireless LC sensors, that comprises a plurality of thin-film layers of elastomeric material and at least one layer of micro-wrinkled electrically conductive material. The method includes steps leading to 2D wrinkled metallised polydimethylsiloxane (PDMS) layers enabling considerable flexibility with negligible bending failure for angles up to 180 degrees.

A method of forming an oral device to measure biological variables includes providing a mold configured to impart a contour of an oral retainer sized to extend about a plurality of teeth. The method includes removing the first layer of the retainer from the mold. The method includes attaching at least one sensor to the retainer, the sensor having a profile and defining a boundary edge. The method includes trimming to form a lip of the first layer of material extending beyond the boundary edge of the at least one sensor component. The method includes attaching the first layer of the retainer and at least one sensor component to the mold, forming a second layer of the retainer with the mold, wherein the first layer of retainer retains the mold contour, and wherein the at least one sensor component is disposed between the first and second layer.

Disclosed is an apparatus for estimating bio-information. The apparatus for estimating bio-information includes: a sensor part comprising a pulse wave sensor array configured to detect a pulse wave signal when an object contacts a contact surface of the sensor part, and a load sensor configured to detect a first contact load applied by the object to the contact surface; and a processor configured to obtain contact load distribution of the contact surface based on the pulse wave signal, and to estimate bio-information based on the contact load distribution.

A needle member includes: a tubular side wall through which a hollow portion extends in a longitudinal direction. An opening portion connected to the hollow portion extends laterally through the tubular side wall. The tubular side wall comprises a side wall reinforcement portion located at a position opposing the opening portion, wherein the hollow portion is interposed between the opening portion and the side wall reinforcement portion.

Brain drainage device having a rod-shaped hollow body with an inner drainage channel for insertion through the cranium into the brain, a first sensor arrangement with at least one sensor for measuring a physical parameter, and a signal interface; wherein the rod-shaped hollow body has a first region A which, in the applied state, is designed to protrude into the ventricle situated in the brain; wherein the rod-shaped hollow body has a second region B, which is arranged proximally from the first region, wherein the second region is designed to lie in the region of the brain mass in the applied state; wherein the first sensor arrangement is arranged in the second region in order to measure a physical parameter of the brain mass; wherein the first sensor arrangement is connected to the signal interface such that measurement data determined by the first sensor arrangement are transmitted to a measuring system that is to be connected.

A sensor includes a sealing tape having a first folding line and a second folding line, and an electronic component adhered to a middle area between the first folding line and the second folding line. A first side area of the sealing tape is folded along the first folding line and adhered to the middle area to cover the electronic component. A second side area of the sealing tape is folded along the second folding line and adhered to the first side area to hermetically wrap the electronic component in the sealing tape.