The present disclosure is directed to a holder. The holder includes a main body, the main body including an interior surface and an exterior surface, a film that extends around at least a portion of the circumference of a first end of the main body and covers an opening of the first end of the main body, and a sheet including a first surface and a second surface, the second surface opposed to the first surface, the first surface operably attached to the seal at at least one point, the sheet configured to extend a distance along an interior of the main body from the first end towards a second end, wherein at least a portion of the first surface of the sheet contacts the interior surface of the main body, and wherein a liquid composition contacts a second surface of the sheet.

Fluid delivery devices and methods are described, where the device may comprise a piezoelectric actuator operatively coupled to an ampoule with fluid, under a preloading force. The ampoule may comprise a thin-walled thermoplastic package which includes one or more apertures positioned on the wall of the ampoule. The piezoelectric actuator may be configured to clamp at least partially around the circumference of the ampoule and apply oscillations to its wall. The oscillations, typically in ultrasonic frequency, produce cycles of acoustic pressure in the fluid, leading to ejection of the fluid droplets or streams from the apertures.

A reclosable container for fluid products is provided. The reclosable container has a containment body provided with a neck ending in a dispensing mouth, and a closure member having a gripping element beneath which lies a stopper tip for closing the dispensing mouth and a removable collar associated with the gripping element along a preestablished break area and rigidly attachable to the neck. In a closed configuration, the dispensing mouth is completely covered by the closure member so that it is not possible for a user's fingers to come into contact with the dispensing mouth when opening the container, avoiding contamination of calibrated drops of the fluid products.

A reclosable container for fluid products is provided. The reclosable container has a containment body provided with a neck ending in a dispensing mouth, and a closure member having a gripping element beneath which lies a stopper tip for closing the dispensing mouth and a removable collar associated with the gripping element along a preestablished break area and rigidly attachable to the neck. In a closed configuration, the dispensing mouth is completely covered by the closure member so that it is not possible for a user's fingers to come into contact with the dispensing mouth when opening the container, avoiding contamination of calibrated drops of the fluid products.

A drug-filled synthetic resin ampule includes an ampule body and a drug 8 filled in the ampule body. The ampule body includes a tip-side sealing portion, a hollow portion, and an annular breakable portion provided between the tip-side sealing portion and the hollow portion. The tip-side sealing portion includes a flat plate portion for grasping formed at an upper portion thereof, and an internal ceiling portion exposed to the interior of the hollow portion. The breakable portion includes an annular smallest diameter portion, and the smallest diameter portion is located near an annular circumferential edge portion of the internal ceiling portion and is located above the annular circumferential edge portion of the internal ceiling portion.

A single-serve portion pack may have a multilayer film structure including a protective layer, a print, a base layer and a peelable seal layer. The print is situated in-between the protective layer and the base layer. The protective layer is a polyalkylene terephthalate based layer having a stress value at 20% strain, at 90 C., comprised between 5 and 20 MPa (preferably between 5 and 15 MPa), and a melting peak temperature comprised between 190 and 240 C. (preferably between 200 and 230 C.).

Embodiments of the present disclosure are directed to coated glass articles which reduce glass particle formation caused by glass to glass contact in pharmaceutical glass filling lines.

Embodiments of the present disclosure are directed to coated glass articles which reduce glass particle formation caused by glass to glass contact in pharmaceutical glass filling lines.

A hermetically sealed thermoplastic container or ampoule having a hollow body portion, a neck portion, unitary with the body portion and terminating in a circumferential, inwardly extending sealing flange, and a removable cap. The neck portion defines an access passageway to the hollow body portion a portion of which is configured as a tapered female connector adapted to receive a tapered male connector when the access passageway is open. The outer surface of the neck portion can be provided with lugs for engaging a tapered male connector with a threaded collar.

A hermetically sealed thermoplastic container or ampoule having a hollow body portion, a neck portion, unitary with the body portion and terminating in a circumferential, inwardly extending sealing flange, and a removable cap. The neck portion defines an access passageway to the hollow body portion a portion of which is configured as a tapered female connector adapted to receive a tapered male connector when the access passageway is open. The outer surface of the neck portion can be provided with lugs for engaging a tapered male connector with a threaded collar.