Devices and methods to extract a desired product from organic matter using supercritical fluid extraction processes are described herein. The extraction vessel generally includes a reaction chamber, a water jacket affixed to the reaction chamber capable of separate pressurization, and a closure mechanism with a gasket, a plug, and a cap ring with ACME threading. The extraction vessel may be sealed by hand closure without a need for additional tools to create a seal able to withstand pressures up to 5,000 psi.

The invention is an improved packaging assembly for storing, distributing, treating, mixing, and dispensing tissue and/or cellular material and/or implantable material. The packaging assembly may include pouches, tubes, and a bag made of a sealable, flexible polymeric material that is open at one end and a needle-free swabable connector attached to the pouch at the other end and acting as a port to allow for the introduction or discharge of biological solutions, rinsing solution, and/or preservation solutions into the packaging assembly. The designed thickness of the wall of the packaging assembly facilitates efficient heat/cold transfer, which is useful for successful controlled rate freezing, quick thawing, and resuscitation of viable cells or tissue. The invention is also useful for combining additional biological fluids with the cellular material or tissue, and for efficient mixing of the biological fluids with the tissue and/or cellular material in the assembly.

The invention is an improved packaging assembly for storing, distributing, treating, mixing, and dispensing tissue and/or cellular material and/or implantable material. The packaging assembly may include pouches, tubes, and a bag made of a sealable, flexible polymeric material that is open at one end and a needle-free swabable connector attached to the pouch at the other end and acting as a port to allow for the introduction or discharge of biological solutions, rinsing solution, and/or preservation solutions into the packaging assembly. The designed thickness of the wall of the packaging assembly facilitates efficient heat/cold transfer, which is useful for successful controlled rate freezing, quick thawing, and resuscitation of viable cells or tissue. The invention is also useful for combining additional biological fluids with the cellular material or tissue, and for efficient mixing of the biological fluids with the tissue and/or cellular material in the assembly.

A cap for a screw-threaded container closure or closure plug includes a cap top and an attachment ring. The attachment ring is securingly engageable with the container closure or closure plug. The attachment ring comprises a cam surface and an upwardly facing shoulder above the cam surface. The container closure or closure plug comprises a plurality of lugs engageable by a wrench or other drive tool. Each lug includes a radially inwardly facing guide surface comprising a downwardly and radially inwardly sloping portion and a downwardly facing shoulder extending radially outward below the downwardly and radially inwardly sloping portion. A secure and relatively easy engagement between the cap and container closure or closure plug is thereby obtainable.

A cap for a screw-threaded container closure or closure plug includes a cap top and an attachment ring. The attachment ring is securingly engageable with the container closure or closure plug. The attachment ring comprises a cam surface and an upwardly facing shoulder above the cam surface. The container closure or closure plug comprises a plurality of lugs engageable by a wrench or other drive tool. Each lug includes a radially inwardly facing guide surface comprising a downwardly and radially inwardly sloping portion and a downwardly facing shoulder extending radially outward below the downwardly and radially inwardly sloping portion. A secure and relatively easy engagement between the cap and container closure or closure plug is thereby obtainable.

A threaded closure system includes a threaded opening and a threaded closure, where at least one thread of the threaded opening or the threaded closure has a leading portion with a steeper angle than the rest of the thread.

The invention concerns a plastic closure for fitting on to the neck of a liquid container in positively locking and sealed relationship comprising a head plate (1) provided for covering a container opening and an outer seal (7) which is circumferential along the edge of the head plate (1) and is provided for engagement with the outside of a container neck (20) defining the container opening, and an inner seal (5) which is circumferential within the outer seal (7) and parallel thereto and which is provided for engagement with the inside of the container neck, wherein the outer and the inner seals (7, 5) respectively extend approximately perpendicularly or slightly inclined from an inside (11) of the head plate (1). To provide a closure and also a container having a closure which generally prevent the closure being blown off under a high positive pressure it is proposed according to the invention that the outer seal (7) has a weakened region (6, 6, 6) in at least one circumferential portion so that the outer seal (7) becomes unsealed at a lower internal positive pressure than when the outer seal is of a configuration without the weakened region.

The invention concerns a plastic closure for fitting on to the neck of a liquid container in positively locking and sealed relationship comprising a head plate (1) provided for covering a container opening and an outer seal (7) which is circumferential along the edge of the head plate (1) and is provided for engagement with the outside of a container neck (20) defining the container opening, and an inner seal (5) which is circumferential within the outer seal (7) and parallel thereto and which is provided for engagement with the inside of the container neck, wherein the outer and the inner seals (7, 5) respectively extend approximately perpendicularly or slightly inclined from an inside (11) of the head plate (1). To provide a closure and also a container having a closure which generally prevent the closure being blown off under a high positive pressure it is proposed according to the invention that the outer seal (7) has a weakened region (6, 6, 6) in at least one circumferential portion so that the outer seal (7) becomes unsealed at a lower internal positive pressure than when the outer seal is of a configuration without the weakened region.

A portable bubble water bottle of the present application includes a first space, a second space, an one-way gas valve and a gas cylinder. The second space is located in the first space along the first projection direction. The one-way gas valve connects the first space with the second space. The gas cylinder is located in the second space, and has a gas outlet connected to the one-way gas valve.

A freshness plug includes a solid round body having an internally depressed section, a protrusion extending from the internally depressed section, a shoulder extending from an exterior of the internally depressed section, and malleable flanges below the shoulder.