Described is an automated reagent mixing container for separately storing and automatically mixing together at least two stored reagent components.

Container, including a body delimiting a cavity to contain fluid substance. A mobile bottom, inside the cavity, sealedly movable along the body internal wall. The body sealedly coupled to a collar having a surface resting on the body and a tubular member extending from the bottom thereof. The tubular member defining a first passage through which the fluid substance flows in use. An insert housed within the collar and formed of first and second parts, connected by a first breakable portion. A shutter housed, in a sealed manner, inside the insert and formed of first and second sections mutually connected by a second breakable portion. The second section including a surface to cooperate, in a sealed manner, with the tubular member when the second section is fitted thereon and a breakable wall which, when broken, permits access to the cavity.

A medicine container closure device for recording and broadcasting information about the contents of a container includes a housing that defines an interior space. The housing is configured to couple to a bottle to selectively close the bottle. A power module and a recording-playback assembly are coupled to the housing and are positioned in the interior space. The recording-playback assembly is operationally coupled to the power module. The recording-playback assembly is configured to record and broadcast information regarding the contents of the bottle, such as a name, a usage, a purpose, and a date to refill the contents.

A dispensing closure system includes an upper closure portion and a lower closure portion including an axial flow conduit and a vent conduit. The upper closure portion is axially movable relative to lower closure portion between shipping and dispensing positions. A seal is disposed on the lower closure portion over the flow and vent conduits. A peripheral spacing strip is removably secured to the upper closure portion and engages with either the lower closure or the outside of the container to prevent movement. A piercing probe includes piercing elements in alignment with the flow and vent conduits for piercing the seal. In the shipping position, the piercing elements are spaced from the seal. However, when the spacing strip is removed and the upper closure portion is axially moved to the dispensing position, the piercing elements pierce the seal to open the flow conduit and the vent conduit.

A receptacle for minimizing evaporation of a fluid includes a single-piece body, a fluid-tight seal, a penetrable septum, and a lid coupled to the body. The body includes a first chamber having a first opening. The fluid-tight seal is affixed to a surface of the body that defines the first opening. The fluid-tight seal covers the first opening and is frangible. The septum covers the first opening and the fluid-tight seal. The lid has an opening axially aligned with the first opening. The septum comprises slits forming flaps The first chamber can be the only chamber containing a fluid, or the single-piece body may also include another chamber containing the fluid. The other chamber can be in fluid communication with the first chamber via a conduit. The fluid-tight seal can also cover the opening of the second chamber.

A packaging system includes a container having a closed end an open end, a longitudinal axis running through the closed end and the open end, and an outer surface. A closure assembly fitted to the open end of the container has an access port. The system also includes a detachable cap disposed over the access port, and a label disposed about the container, characterized in that the label has a first region angled relative to the longitudinal axis, which first region consists essentially of a name of an injectable drug product, and a second region angled relative to the longitudinal axis, which second region consists essentially of a concentration of the injectable drug product, whereby the said first and second regions are angled such as to lie in planes that make non-zero as well as non-right angles with the longitudinal axis.

A packaging system includes a container having a closed end an open end, a longitudinal axis running through the closed end and the open end, and an outer surface. A closure assembly fitted to the open end of the container has an access port. The system also includes a detachable cap disposed over the access port, and a label disposed about the container, characterized in that the label has a first region angled relative to the longitudinal axis, which first region consists essentially of a name of an injectable drug product, and a second region angled relative to the longitudinal axis, which second region consists essentially of a concentration of the injectable drug product, whereby the said first and second regions are angled such as to lie in planes that make non-zero as well as non-right angles with the longitudinal axis.

A dispensing closure system includes an upper closure portion and a lower closure portion including an axial flow conduit and a vent conduit. The upper closure portion is axially movable relative to lower closure portion between shipping and dispensing positions. A seal is disposed on the lower closure portion over the flow and vent conduits. A peripheral spacing strip is removably secured to the upper closure portion and engages with either the lower closure or the outside of the container to prevent movement. A piercing probe includes piercing elements in alignment with the flow and vent conduits for piercing the seal. In the shipping position, the piercing elements are spaced from the seal. However, when the spacing strip is removed and the upper closure portion is axially moved to the dispensing position, the piercing elements pierce the seal to open the flow conduit and the vent conduit.

Disclosed is a device useful for preserving tissue samples after extraction from human or animal patients. The device includes a circular blade for taking a tissue sample, the blade being coupled to a sealing cap which mates to one end of a container. A retrieval port is also disclosed for extracting fluids from the container. Methods are also disclosed by which tissue samples may be taken and prepared for storage, processing, culture, or other analysis.

An oral care implement that includes a head having a face with a tuft hole therein. A plurality of bristles are disposed within the tuft hole and arranged in a bristle tuft that extends from the face of the head. The bristle tuft includes a first subset of the bristles and a second subset of the bristles. Each of the bristles has a longitudinal axis and a transverse cross-sectional profile having a major axis and a minor axis, the major axes of the bristles being longer than the minor axes of the bristles. The major axes of the bristles of the first subset may be non-parallel to the major axes of the bristles of the second subset.