A vial assembly may include a vial having a body to hold a liquid material, and a neck extending from the body. The neck may include a multi-use surface configured to permit access to the liquid material. The vial assembly may include a cap to be received by the neck and to cover the multi-use surface. The cap may include a base having a first major surface, and a second major surface opposite of the first major surface, arms extending from the second major surface, and a rupturable reservoir of disinfectant material carried by the base between the first major surface and the second major surface. One or more of the first major surface and the second major surface may be flexible so as to rupture the rupturable reservoir when the cap is received by the neck.

A closure assembly for a cell culture apparatus includes a port and a snap cap. The port has an annular sidewall defining an opening in communication with a cell culture chamber of a cell culture apparatus. The sidewall has (i) external threads for cooperating with internal threads of a twist cap and (ii) an annularly protruding snap cap engagement feature. The snap cap has a top and an annular sidewall extending from the top. The sidewall of the snap cap has an inwardly annularly projecting element configured to engage with the annularly protruding snap cap engagement feature of the port such that, when fully engaged, the snap cap is not readily removed from the port by unaided human force.

A primary packaging container for pharmaceuticals is provided. The container includes a hollow body, an opening, and a closure. The hollow body has an opening and is made of a cycloolefin polymer or a cycloolefin copolymer. The closure has a puncture region. The closure closes the opening with the puncturing region at the opening. The puncturing region is configured to allow introduction of a cannula into the hollow body and resealing the hollow body upon withdraw of the cannula. The closure has an elastomer that is connected to the hollow body so as to be not separable in a non-destructive manner.

A pierceable cap 11 may be used for containing sample specimens. The pierceable cap 11 may prevent escape of sample specimens before transfer with a transfer device 43. The pierceable cap 11 may fit over a vessel 21. An access port in the shell of the pierceable cap 11 may allow passage of a transfer device 43 through the pierceable cap 11. At least one frangible layer 215, 216 may be configured with cross slits 506 in a particular cross slit geometry. The cross slits 506 may contain an openable portion 644 or be covered by a thin membrane 645. The shell 610 and frangible layer(s) 215, 216 may be integrated into a one piece cap 601, or be separate components 634. The membrane on which the cross slits 506 are placed can be flat or contoured to guide the transfer device 43 to the cross slits 506.

A plastic container product, in particular produced by a blow molding, filling and sealing method, comprising a container body (10) having a content of the container and an adjoining head part (12) which delimits an extraction area (14), which is closed by a head membrane (16), which has a connecting seam (38), which passes through a plane (20) spanned by the head membrane (16) and separates at least two penetrable areas (22, 24) on the free end face (26) of the head membrane (16) from each other for extracting the content of the containers, characterized in that the connecting seam (38) seen on the free end face (26) of the head membrane (16) has a course of the seam (36) at least partially deviating from a fictitious rectilinear course (32) extending within this plane (20), which is longer than the rectilinear course (32) and at least partially comprises the penetrable areas (22, 24).

A toothbrush comprising a bristle having a cross-sectional profile with a major axis and a minor axis. In one embodiment, the invention can be an oral care implement comprising: a head; a handle; and at least one bristle extending from a face of the head, the bristle having a longitudinal axis and a transverse cross-sectional profile having a major axis and a minor axis, the major axis being longer than the minor axis.

A device for deterring drug abuse includes a housing configured to contain a drug accessible through an access port. The device includes a physical deterrent configured to move from an unsecured position, wherein the access port of the housing is normally accessible, to a secure position, wherein the access port of the housing is normally inaccessible. The device further includes a locking mechanism that is coupled with the physical deterrent. The locking mechanism has a locked mode, wherein the physical deterrent does not normally move from the secure position to the unsecured position. The locking mechanism is further coupled with a deterrent container having a deterrent substance. The device is configured such that attempts to access the drug when the physical deterrent is in the secure position, and when the locking mechanism is in the locked mode, activate the release of the deterrent substance to the drug.

Described is an automated reagent mixing container for separately storing and automatically mixing together at least two stored reagent components.

A needle includes a hollow needle body. The needle body includes a sharp and a proximal end portion located opposite the sharp and defining an opening. The needle body has at least one thru hole and a lumen. The thru hole is located at or proximate the sharp. The lumen is provided between the thru hole and the opening of the end portion. The needle body is constructed of a blend of a polymeric base material for providing flexibility, and a fiber material for providing rigidity.

A closure having a base with a piercable part, defined by a sidewall extending transversally with respect to the base and a bottom thereby creating an indent therein, the sidewall and/or bottom provided with several lines of weakened material strength, wherein the lines divide the sidewall and/or bottom in several wedge formed parts.