A method reduces microbiological contamination in a closed chamber (6), formed by at least two interconnected components (1, 4), by introducing a germicidal medium in liquid form into the chamber (6). The chamber (6) is formed by and between a cap (4) and a head (2) of a filled container.

An obturation element (1) for a well receiving a chemical or biological solution to be analyzed, including for each well, a plug (4) including an insertion sleeve (5) in the form of a cylinder provided with two truncated areas (15) arranged in a symmetrically opposite manner on the outside of the sleeve to form vents, this insertion sleeve (5) being provided with a bottom wall (9) in which a through-cutout (18) is arranged, oriented radially in the direction of the two truncated areas (15).

A fitment device may include a core formed from a first material having a first low permeability of oxygen. The core may include a securing portion configured to secure to a chassis, and a container portion including at least one side portion at least partially coated with a second material configured to seal to a container, wherein the first material is different than the second material and includes a different gas permeability of oxygen. An aperture may extend between the securing portion and the container portion. Reagent cartridges and methods of manufacturing and using fitment devices are also disclosed.

A sealing cap for a container for holding a medical liquid comprising a cap body, which bounds an interior and has at least one opening, and at least one connection device, which is arranged on the cap body and to which a conveying device for feeding a medical liquid into the container or for removing a medical liquid from the container can be connected. The connection device has a sealing element, arranged on the cap body. The connection device has a break-off piece, which, in an initial state, is firmly connected to the cap body and covers the outer face of the sealing element in the outward direction. The break-off piece is connected to the cap body by means of a pre-determined breaking point. In addition, the sealing element is convex on the outer face.

A hooking and piercing device (1) for vials and tubes provided with a closing cap openable by pressure, comprising a hooking hood (2) with circumferentially distributed hooking toothed sectors (3) and an axial perforated stem (4) which extends axially and centrally out of the hooking hood (2) to be engaged by pressure inside a tube. The axial perforated stem (4) has an axially perforated appendix (6) which extends inside the hooking hood (2) and is shaped like a syringe luer. A frangible closing element (17) on the axial perforated stem (4) may be provided at the end of the axial perforated stem (4) opposite to the one with the luer-shaped appendix (6).

Example apparatus including septums and related methods are disclosed. An example apparatus includes a septum that includes a first surface and a membrane coupled to at least a portion of the first surface. In addition, the example septum includes a second surface and ribs extending between the membrane and the second surface.

The present application relates to a system for dispensing fluid. The system includes a flexible container including a spout that is in fluid communication with an interior region of the container. The system includes a cap configured to be mounted to the spout. The cap includes an opening that leads to a membrane and a first retention mechanism located in the opening. The system includes a piercing tube having a first end configured to puncture the membrane and a second end configured to be connected to a dispensing tube. The piercing tube includes a seal bead and a second retention mechanism. The piercing tube is inserted into the opening of the cap such that the first end punctures the membrane, the first and second retention mechanisms engage each other to retain the piercing tube in the cap, and the seal bead sealingly engages the cap.

A pierceable self-resealing stopper for a container is disclosed. The disclosed stopper is suitable for sealing a container containing reagents for use in a high-throughput analysis system in which reagents in the container are accessed by an aspirator probe piercing the stopper. The stopper is configured for being pierced and resealing itself a large number of times without degradation of the stopper by coring or fragmentation, for example. A set of protrusions extending from a top surface of the stopper is depressed to stretch a thin diaphragm area between the protrusions prior to and during insertion of the probe. After extraction of the probe, the protrusions are allowed to return to a relaxed state, which discontinues stretching of the diaphragm area and reseals the container.

A system includes a cap for a medical fluid container and an attachment part. The cap includes at least one first port. The first port includes a septum and a connection structure. The attachment part includes a hollow spike and a joining structure in fluid communication with the hollow spike. The joining structure is configured for connecting the device for withdrawing fluid from the fluid container and/or for supplying fluid into the fluid container. The connection structure is configured to be connected to a complementary connection structure of the attachment part in a releasable or non-releasable manner such that the hollow spike of the attachment part pierces the septum.

A cap assembly includes an access member configured for attachment to a reservoir. The access member includes a first port that enables needleless extraction of contents from the reservoir, and at least one second port that enables needled extraction of the contents from the reservoir. The cap assembly further includes a valve member positioned in or configured to be positioned in the access member to i) enable needleless extraction of the contents of the reservoir through the first port when the first port is attached to a needless extraction device, ii) enable needled extraction of the contents through the at least one second port, and iii) seal the contents of the reservoir at the first port and at the at least one second port prior to and subsequent to the needleless or needled extraction.