A bladder having a fluid impermeable material layer that is compatible with a liquid held in the bladder and at least one impact protection layer that is conformally arranged to span a surface area of the liquid impermeable material.

Packaging sheets, packaging material comprise one or more packaging sheets and related methods are provided herein. A packaging sheet can include a first substrate having a first surface and an opposing second surface. An adhesive layer can be applied on the first surface of the first substrate. A cohesive layer can he applied on the adhesive layer, such that the cohesive forms a first outer surface of the packaging sheet with the opposing second surface of the first substrate forming a second outer surface. The packaging sheets can, in some embodiments, comprise body bag sheets used to form body bags.

Packaging sheets, packaging material comprise one or more packaging sheets and related methods are provided herein. A packaging sheet can include a first substrate having a first surface and an opposing second surface. An adhesive layer can be applied on the first surface of the first substrate. A cohesive layer can he applied on the adhesive layer, such that the cohesive forms a first outer surface of the packaging sheet with the opposing second surface of the first substrate forming a second outer surface. The packaging sheets can, in some embodiments, comprise body bag sheets used to form body bags.

A flexible container is provided. The flexible container includes four panels. The four panels form (i) a body portion; (ii) a neck portion, and a flare portion that extends from the neck portion; (iii) a tapered transition portion between the body portion and the neck portion; and (iv) the neck portion has a reduced width. The flare portion has an expanded end. The width of the flare portion gradually increases from the neck portion to the expanded end.

A flexible container is provided. The flexible container includes four panels. The four panels form (i) a body portion; (ii) a neck portion, and a flare portion that extends from the neck portion; (iii) a tapered transition portion between the body portion and the neck portion; and (iv) the neck portion has a reduced width. The flare portion has an expanded end. The width of the flare portion gradually increases from the neck portion to the expanded end.

A method of forming and filling a pouch, comprises forming opposing walls of a film; sealing the opposing walls of film together to form at least one pouch; filling an interior section of the at least one pouch through an opening in an upper portion of the at least one pouch with a flowable material; forming a top sealed expressing-shaped region to close the opening in the at least one pouch; and cradling the pouch with a foldable flat that is more rigid than the pouch that can be folded or rolled to compress the pouch to express the flowable material through the expressing shaped region.

A method of forming and filling a pouch, comprises forming opposing walls of a film; sealing the opposing walls of film together to form at least one pouch; filling an interior section of the at least one pouch through an opening in an upper portion of the at least one pouch with a flowable material; forming a top sealed expressing-shaped region to close the opening in the at least one pouch; and cradling the pouch with a foldable flat that is more rigid than the pouch that can be folded or rolled to compress the pouch to express the flowable material through the expressing shaped region.

A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.

A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.

A packaging product and a method of closing a packaging product are provided. Closing a packaging product may include providing a first member of the packaging product having an aperture therein and providing a bubble rivet extending through the aperture and having an expanded hollow head portion on one side of the aperture with a neck portion of the bubble rivet being provided in the aperture. The hollow head portion of the bubble rivet is breakable to enable withdrawal of the head portion through the aperture thereby non-reversibly opening the packaging product.