A mill blank may have a multilayer structure and desirable aesthetics. Such dental mill blanks may include a mill blank portion having a layered structure of two or more layers, and in which the layered structure includes an enamel layer and a core layer, the core layer comprising a first portion that is substantially a frustum, the frustum having a side face forming a part of an interface between the enamel layer and the core layer.

The present invention relates to a block (1) for the CAD/CAM machining of a dental prosthetic element: an insert (2) wherein the dental prosthetic element is intended to be machined, a polymeric layer (5) covering at least one surface of the insert, a mandrel (6) fixed to the insert (2),

characterised in that the insert (2) comprises two parts (3, 4) connected to one another, of which: a first part (3) intended to be machined to form an inlay-core, said first part comprising a composite material comprising one-directional reinforcing fibres, a second part (4) intended to be machined to form a crown, said second part having no reinforcing fibres and comprising a material comprising one or more mineral fillers.

A dental crown and method of use thereof. According to the method provided herein, a dental crown is selected having an appropriate size and shape and an internal contour. The tooth to which the crown is to be applied is prepared to have an external contour. Composite material is injected into the internal contour of the dental crown. The dental crown is placed over the prepared tooth and the deposited composite material is cured using light.

The present invention provides devices and methods for controlled and continuous delivery of drugs into the brain by bypassing the blood brain barrier, without the need for any surgical manipulation of the brain. The respiratory mucosa in the maxillary sinus or in the nasal region is surgically accessed from the oral or maxillofacial region through a window made on the bone overlying the mucosa. The device is used to deliver drugs in a continuous and controlled manner either beneath or above the respiratory mucosa depending on the clinical requirements, drug formulation and the volume of drug used. The drug distributes into the brain from the delivery site by bypassing the blood brain barrier without causing any significant increase of the drug in the peripheral circulation. The device can be used for continuous and controlled drug delivery into the brain by bypassing the blood brain barrier for a number of medical conditions.

The invention relates to a method for the production of a blank of a ceramic material, wherein a first ceramic material and then a second ceramic material of different compositions are filled into a mold and wherein the materials are pressed and after pressing are sintered. Thereby, a layer of the first ceramic material is filled into the mold, a first open cavity is formed in the layer, the second ceramic material is filled into the first open cavity and the materials are pressed together and are then heat-treated. Both the first ceramic material and the second ceramic material contain, or consists of, lithium silicate glass ceramic.

The invention relates to a method for the production of a blank of a ceramic material, wherein a first ceramic material and then a second ceramic material of different compositions are filled into a mold and wherein the materials are pressed and after pressing are sintered. Thereby, a layer of the first ceramic material is filled into the mold, a first open cavity is formed in the layer, the second ceramic material is filled into the first open cavity and the materials are pressed together and are then heat-treated. Both the first ceramic material and the second ceramic material contain, or consists of, lithium silicate glass ceramic.

Methods and systems for tracking a dental tool within an oral cavity for taking and/or updating of a dental impression are described. In some embodiments, a marker, optionally a magnetic marker, is coupled to position movements of a rotatable dental tool. In some embodiments, detected movements of the marker are used, optionally in combination with other tracking data, to map contours which a portion of the rotatable dental tool follows during interaction with a dental surface. Optionally, the interaction occurs during grinding, drilling, and/or other procedures; which may be preparatory, for example, to the manufacture and/or fitting of a dental prosthetic.

Methods and systems for tracking a dental tool within an oral cavity for taking and/or updating of a dental impression are described. In some embodiments, a marker, optionally a magnetic marker, is coupled to position movements of a rotatable dental tool. In some embodiments, detected movements of the marker are used, optionally in combination with other tracking data, to map contours which a portion of the rotatable dental tool follows during interaction with a dental surface. Optionally, the interaction occurs during grinding, drilling, and/or other procedures; which may be preparatory, for example, to the manufacture and/or fitting of a dental prosthetic.

A composition includes granules in which zirconia particles are aggregated. The granules have an average circularity of 0.81 or greater based on a projected image.

A composition includes granules in which zirconia particles are aggregated. The granules have an average circularity of 0.81 or greater based on a projected image.