Systems and methods for removing aerosolized particles from a treatment zone may be employed with dental, medical or veterinarian procedures. An exemplary system may include a hood and corresponding evacuation system that creates a negative-pressure current that draws aerosolized particles away from a treatment zone and into the evacuation system. Such an exemplary system may also include an air curtain generator that creates a curtain comprising streams of pressurized air around the treatment site that may help to direct aerosolized particles into the hood and evacuation system and prevent many such aerosolized particles from escaping the curtain.