A poultry treatment apparatus is disclosed herein. In various aspects, the poultry treatment apparatus may include a tank forming a reservoir at ambient pressure and containing liquid. A pump may be in fluid communication with the tank, and the pump may be in fluid communication with a liquid intake of a first nozzle, and in fluid communication with a liquid intake of a second nozzle to supply liquid under pressure from the tank to the liquid intake of the first nozzle and to the liquid intake of the second nozzle. A compressor may be in fluid communication with an air intake of the first nozzle and with an air intake of the second nozzle to supply compressed air to the air intake of the first nozzle and to the air intake of the second nozzle. In various aspects, the combination of compressed air and liquid under pressure deliver spray from the first nozzle and deliver spray from the second nozzle, and the first nozzle and the second nozzle deliver about the same flow rate of liquid with droplets of similar size. The first nozzle is secured to a boom at a first elevation to deliver spray into a first tier, and a second nozzle secured to the boom at a second elevation to deliver spray into a second tier, the second tier being at a different elevation than the first tier, in various aspects. The tank, the compressor, the pump, and the boom are attached to a cart traversable to deliver spray simultaneously to poultry contained on the first tier and poultry contained on the second tier, in various aspects.

Embodiments of the invention provide multi-stage biodegradable drug delivery platforms and methods for the subcutaneous delivery of therapeutic agents (TA). Embodiments of the platform may be configured to subcutaneously deliver a first dose of a first TA which is absorbed into the body and/or blood stream (BBS) to produce a first therapeutic effect for a first selectable time period (STP), and subsequently after a second STP, deliver a second dose of a second TA which is absorbed into the BBS to produce a second therapeutic effect for a third STP. An embodiment of the platform may comprise a body having a tissue-penetrating end, a primary cavity having a first TA dose and a shell having a secondary cavity having a second TA dose. The first TA dose is released after the first STP and the second TA dose is released after the second STP by biodegradation of the shell.

The disclosure relates to a spray applicator system for accurately and precisely dosing liquid formulations, including vaccines and probiotic formulations, to caged avian animals. In particular, the disclosure relates to spray applicators, having improved acceptance by the avian animals, relative to more disruptive prior spray applicators. The disclosed automated caged spray applicator system is designed to attach to and function with automated poultry feeding systems, routinely used in poultry house settings.

The present invention is directed to a method of treating poultry hatchlings in a hatchling tray. The method comprises of providing a soft gel form capable of being dispensed through a spray nozzle, providing a spray dispensing apparatus, the apparatus being capable of delivering a predetermined volume of the gel as a plurality of small beadlets through a plurality of nozzles, placing the hatchling tray containing the hatchlings beneath the nozzles of the dispensing apparatus, dispensing the predetermined volume of the soft gel containing the therapeutic agent as small beadlets into the hatchling tray and allowing the hatchlings to consume the beadlets. The present invention is also directed to a dispensing apparatus for dispensing a therapeutic agent in a soft gel into a hatchling tray of poultry hatchlings.

A needleless injector which can selectively induce the immune response and a method for introducing DNA including a region coding for an antigen to selectively produce an antibody in a living body of a mammal by using the needleless injector are provided. Disclosed is a needleless injector for injecting a DNA solution into an injection target area without using any injection needle. The needleless injector includes an accommodating unit which accommodates the DNA solution, a predetermined ignition device and a predetermined nozzle unit. A temperature of the predetermined combustion product, which is provided during the pressurization, changes to a neighborhood of ordinary temperature within 20 msec after a pressure, which is applied to the DNA solution on account of the combustion of the igniter powder, reaches an initial peak discharge force during a pressurization process for discharging the DNA solution.

A tissue-removing catheter includes a drive assembly operatively connected to a drive shaft to impart rotation and reciprocation to the drive shaft and thereby rotate and reciprocate a tissue-removing element of the catheter. The drive assembly includes a prime mover configured to generate a rotational drive force and a reciprocating rotor operatively connected to the prime mover to receive the rotational drive force. The rotor is also operatively connected to the drive shaft to impart rotation and reciprocation to the drive shaft. The drive assembly can include a stator configured to constrain rotation and reciprocation of the reciprocating rotor relative to an axis of the rotor. The rotor can define a race that extends around the rotor axis, and the stator can define one or more bearing projections that track through the race as the prime mover rotates the rotor about the rotor axis to drive reciprocation of the rotor.

A tail vein injection system includes at least one memory; and at least one processor connected to the at least one memory. The at least one processor is configured to: calculate information including a position of a tail vein based on one or more images of a tail; adjust a position and a posture of a syringe needle based on the calculated information; and after the adjusting, perform a puncture of the tail vein using the syringe needle.

An atherectomy catheter for use in a vessel includes a catheter body, a nosecone and an annular cutter. The catheter body has a curved portion with a fixed jog section and an adjacent flexible section having a greater flexibility than a remainder of the catheter body. The fixed jog section and the flexible section include a frame having circumferential slits arranged in rows and in a circumferentially offset pattern. The circumferential slits of the flexible section are configured to allow the flexible section to passively bend in multiple directions during positioning of the catheter body within the vessel. The fixed jog section further includes a longitudinal spline having a pre-set curvature. The nosecone is attached to a distal end of the catheter body and includes a cutting window. The annular cutter configured to rotate with respect to the catheter body and positioned within the cutting window.

An atherectomy catheter for use in a vessel includes a catheter body, a nosecone and an annular cutter. The catheter body has a curved portion with a fixed jog section and an adjacent flexible section having a greater flexibility than a remainder of the catheter body. The fixed jog section and the flexible section include a frame having circumferential slits arranged in rows and in a circumferentially offset pattern. The circumferential slits of the flexible section are configured to allow the flexible section to passively bend in multiple directions during positioning of the catheter body within the vessel. The fixed jog section further includes a longitudinal spline having a pre-set curvature. The nosecone is attached to a distal end of the catheter body and includes a cutting window. The annular cutter configured to rotate with respect to the catheter body and positioned within the cutting window.

A handling device for poultry animals, in particular for supporting manual handling of poultry animals, is disclosed, along with a method for handling poultry animals, in particular manually, and the use of the handling device. The handling device includes a guide rail, extending between a first end and a second end, with two guide legs, and a poultry animal support for placing the breast area of a poultry animal thereon.