A method and device for augmentation or rejuvenation of vaginal tissue, which applies negative pressure through a plurality of channels of a hollow body against a region of the vaginal wall to cause microtrauma, edema, or hypertrophy; and optionally introducing a dermal filling or adipose tissue into the vaginal tissue where the region of edema and hypertrophy occurs and while the region remains swollen from the applied pressure.

The disclosure relates to a device for creating an intradermal channel in a skin tissue of a patient, with a thread. The device can include a main body, a penetration element, and a displacement mechanism. The main body can have a lumen. The penetration element can be at a distal end of the main body and have a cannula which is configured to contain the thread in its entirety. The displacement mechanism can have at least a portion thereof permanently contained within the lumen of the main body. The displacement mechanism can be configured to effect a relative motion between the cannula and the thread, thereby to expose at least a portion of the thread to a patient's tissue within an intradermal channel.

The present disclosure relates to a three-dimensional, degradable medical implant for regeneration of soft tissue comprising a plurality of volume-building components and a mesh component which is substantially made of monofilament or multifilament fibers, wherein each volume-building component is attached to at least one point on a surface of the mesh component, and wherein the projected surface area of each volume-building component, when projected on the surface of the mesh component, corresponds to a maximum of one tenth of the surface area of the mesh component.

Medical devices are provided, comprising a medical device and a sensor.

A method of fabricating an object from a heat curable polymer such as silicone is provided. The method is carried out by using additive manufacturing to fabricate a portion of a mold and filling the portion of the mold with the heat curable polymer. The polymer is then heated and the steps of mold fabrication and filling are repeated until the object is fabricated.

A hybrid medical device that can aid in reconstructive or augmentative surgery of the breast is disclosed. The device can utilize a suitable biological collagen tissue matrix combined with a synthetic material, for example, that can impart a high initial strength to the repair site while permitting proper healing and revitalization of the implanted device.

An insertable catheter device includes a shaft including a proximal end and a distal end, an expandable balloon, and an actuator configured to expand and retract the expandable balloon. The actuator includes a fluid conduit that extends through the shaft and is coupled with the expandable balloon to enable inflation and retraction of the expandable balloon via injection or withdrawal of a fluid to or from the expandable balloon via the fluid conduit. The expandable balloon is displaceably retractable into the shaft and extendable from the shaft. A fluid pump is coupled with the fluid conduit to pump the fluid through the fluid conduit. A patch is positioned to be displaced by the expandable balloon when the expandable balloon is inflated, and the expandable balloon is displaceably retractable into the shaft and displaceably extendable from the shaft.

The present invention relates to a hyaluronic acid-based hydrogel which is a hyaluronic acid-peptide crosslinked body crosslinked using a peptide crosslinking agent. More specifically, the present invention relates to a hyaluronic acid-based hydrogel and a method for producing same, wherein a crosslinked body having novel physical properties is obtained using a relatively small amount of a crosslinking agent that forms peptide bonds, unlike conventional crosslinking agents, and the hyaluronic acid-based hydrogel has the advantages of: being safe and having few side effects; the physical properties of a filler being adjustable according to the amount of peptide crosslinking; and having a high elasticity ratio.

A void occlusion device that includes a scaffold defining a plurality of voids and a reinforcement member is described. The scaffold is configured to permit the infiltration of human tissue into the plurality of voids. The reinforcement member extends through at least a portion of the scaffold and is configured to resist compressive forces exerted on the scaffold. Also described are embodiments where the void occlusion device is biocompatible, bioresorbable, elastic, and suitable for radio imaging.

Improved breast prostheses, methods of making breast prostheses, and methods of treatment using such breast prostheses are described.