A method of treating prolapse of a vagina is provided by placing a reinforcing implant inside of the vagina. The method includes inserting a porous sheet of material inside of the vagina through a natural vaginal opening of the patient. The porous sheet of material is an implantable support that is adapted to integrate with tissue inside of the vagina to reinforce and support at least an apical portion of the vagina. The method includes maintaining the apical portion of the vagina in an anatomically natural position by supporting the porous sheet of material inside of the vagina relative to one of a sacrum and a ligament of the patient.

In a method and system for producing an implant, the latter is designed with one or more surfaces extending in the longitudinal direction of the implant. Two or three production stages can be used. In one stage, either a topography with a long wave pattern is produced by means of cutting work, or laser bombardment or further cutting work is used to produce a topography with an intermediate-length wave pattern. In addition, an oxidation process or shot-peening or etching is used to produce an outer layer. When using two of said production stages, said cutting work or said laser bombardment or further cutting work is followed by the oxidation process or the shot-peening or etching method. When using all three production stages, cutting work is followed by laser bombardment, or further cutting work, which in turn is followed for example by the oxidation process. The invention also relates to an implant which is produced using the method and is identified, ordered and produced using the system. The invention permits effective treatment of different implant situations.

The present invention relates to a method of implanting a penile implant for curing impotence of a patient. The method comprises the steps of cutting a skin of the patient, dissecting an area of a corpus cavernosum of a penis of the patient, implanting the penile implant in the corpus cavernosum. The penile implant is implanted by placing a relatively short proximal portion of the penile implant in the root of the penis, placing a flexible relatively long distal portion of the penile implant such that it extends along or in the pendulous or protruding part of the penis.

Systems and methods are disclosed to protect a medical device from scarring a body after implanting the device in the body by creating a bonding matrix on a surface of the device; exposing the surface to hyaluronic acid (HA) or polyethylene glycol (PEG); cross linking the HA or PEG; and preventing capsular contracture after implanting the device in the body.

A scaffolded stent-graft includes a graft material comprising an inner surface and an outer surface. The inner surface defines a lumen within the graft material. The scaffolded stent-graft further includes a scaffold comprising a mesh coupled to the graft material at the outer surface. The scaffold is configured to promote tissue ingrowth therein. In this manner, the scaffold enhances tissue integration into the scaffolded stent-graft. The tissue integration enhances biological fixation of the scaffolded stent-graft in vessels minimizing the possibility of endoleaks and migration.

A medical device for inserting into a hollow organ of the body, said medical device having a compressible and expandable lattice structure made of webs, which are integrally connected to each other by web connectors and which bound closed cells of the lattice structure, wherein the web connectors each have a connector axis extending between two cells which, in a longitudinal direction of the lattice structure, are adjacent to each other. During the transition of the lattice structure from the production state to a compressed state, the web connectors rotate in such a way that an angle between the connector axis and a longitudinal axis of the lattice structure changes, in particular increases, during the transition of the lattice structure from a completely expanded production state to a partially expanded intermediate state.

The invention relates to an implantable prosthetic device for the repair of connective tissue in an animal or a human. In one embodiment, an implantable prosthetic device (100) for the repair of connective tissue (500) in an animal or human is disclosed which comprises a biocompatible pad (101) having an open structure to provide a scaffold for the in-growth of tissue into the pad; and a reinforcement region (206) attached to or formed integrally with the pad. The device is arranged so that it can be attached to tissue by forming a puncture (301) either a) within the reinforcement region, or b) in an area of the pad which is inboard of the reinforcement region, so that a suture (300) can be located through the puncture, the reinforcement region serving to support tensile loading in the device during use by resisting pull-through of the suture.

A new titanium-based implant is disclosed, which is formed by a titanium coating manufactured with biomaterials with applications in osseous implantology. The nanotopographical characteristics of these implants inhibit bacterial adhesion and the formation of a bacterial biofilm on the surface, whilst simultaneously presenting suitable properties for the adhesion, stretching and proliferation of bone-forming cells. Moreover, the invention comprises a method for manufacturing the implant by means of oblique-incidence techniques and the use thereof in osseous implantology.

Compositions including a surface or film comprising nanofibers, nanotubes or microwells comprising a bioactive agent for elution to the surrounding tissue upon placement of the composition in a subject are disclosed The compositions are useful in medical implants and methods of treating a patient in need of an implant, including orthopedic implants, dental implants, cardiovascular implants, neurological implants, neurovascular implants, gastrointestinal implants, muscular implants, and ocular implants.

A method includes mixing a polymer, an organic solvent, and a porogen such that an initial paste is formed. The method also includes in-situ shaping the initial paste; creating a plurality of channels within the shaped paste and removing the organic solvent from the shaped paste such that a solidified perforated paste is formed; and leaching out the porogen from the solidified perforated paste such that a porous scaffold is formed.