There is disclosed a collagen construct comprising a plurality of elongate strips, wherein each strip contains a plurality of collagen fibres that are substantially aligned along the length of the respective strips, and the strips are braided or woven together to produce a collagen construct in the form of a rope that can be used for replacing tendons or ligaments, such as cruciate ligaments. Also disclosed is a method for making or producing the collagen construct from a collagen membrane having a plurality of collagen fibres being substantially aligned parallel to each other in a common direction. The membrane is cut along cut lines that are orientated substantially parallel to that common direction, thereby to separate elongate strips from the membrane. The strips are then braided or woven together to form the collagen construct.

The invention relates to a container (1) for holding a transplant object (2) and to a closure lid (4) and a vessel (3) for such a container (1). To facilitate an improved and reliable analysis and treatment of transplant objects (2), the intention being to implement particularly sparing handling, which is also protected against environmental influences, of the transplant object (2), it is proposed that the container (1) be transmissive for radiation that facilitates radiological imaging and/or a sterilization by means of ionizing radiation of the transplant object (2) held in the container (1) and that the closure lid (4) and/or the vessel (3) have one or more affixment structures (5) for fastening the transplant object (2) in the container (1). Moreover, a method and a system for providing three-dimensional structure data of a transplant object are proposed, by means of which the information obtained by the analysis is rendered better usable for medical staff. Moreover, a method and a system for sterilizing a transplant object (2) by means of ionizing radiation are described.

A tray assembly may include a bottom portion having a bottom wall and first, second, third, and fourth side walls each extending upward from the bottom wall, and a top portion having a top wall and first, second, third, and fourth sides. The top portion is configured to releasably engage the bottom portion. The bottom portion includes at least one notch formed in an upper edge of the first side wall, the at least one notch being configured to receive an elongate shaft of an implant delivery device. A kit for preparing a replacement heart valve implant for delivery may include the tray assembly, at least one rinsing bowl, and a loading tools kit for attaching the replacement heart valve implant to the implant delivery device.

A medical device may include a shaft extending between a proximal end and a distal end. The shaft may include a lumen therein. The medical device may include a handle coupled to the proximal end of the shaft and may include a mode selector. The mode selector may be adapted to transition between a first mode and a second mode of the medical device. The medical device may further include a compressed fluid source. In the first mode, the compressed fluid source may be fluidly coupled with the shaft so as to impart a negative pressure in at least a portion of the lumen. In the second mode, the compressed fluid source may be fluidly coupled with the shaft so as to impart a positive pressure in the at least a portion of the lumen.

A system for heart valve repair includes a packaging assembly for storing the replacement heart valve. The packaging assembly includes a valve support having a base for holding the replacement heart valve, a ring positioned within the valve support and configured to fit around a circumference of the replacement heart valve, and a retention mechanism. The retention mechanism includes a cap and plurality of sutures configured to be attached to the cap and to the replacement heart. The packaging assembly having a locked configuration in which the ring and the valve support are locked together and the sutures tension the replacement heart valve. The packaging assembly is designed to hold and transport a replacement heart valve and fits within a shipment jar.

Aspects of the disclosure relate to storage assemblies including at least part of a delivery device and an implant. The storage assemblies are configured to trap sterilizing ethylene oxide gas using its high water solubility and converting the escaped ethylene oxide to less detrimental ethylene glycol and ethylene chlorohydrin to protect the implant from damage. In one example, the storage assembly includes an inner container housing the implant and sterilizing fluid and an outer container positioned over the inner container, wherein the outer container is at least partially filled with aqueous water. The implant may be a prosthetic heart valve. Aspects of the disclosure also relate to methods of sterilizing the storage assemblies of the disclosure.

Trays and packaging systems for a prosthesis delivery device that permit conversion from a packaged, storage/or shipping configuration to a loading configuration for the loading of a prosthesis. The prosthesis may be a prosthetic heart valve. In the packaged configuration, the delivery device can be supported within the tray, which includes a recess and at least one clip maintaining the delivery device within the recess. In the loading configuration, the delivery device can be arranged for loading of the prosthesis within a bath area of the tray. Optionally, the delivery device can be stored in the packaged configuration in a U-shape. Some embodiments include an additional recess for positioning an indeflator fluid line or tubing. Methods of use are also disclosed.

Ophthalmic tissue delivery devices that include an injector and injector carriers and methods for endothelial keratoplasty surgical procedures are provided. Injectors include a conduit sized to accommodate ophthalmic tissue. One end of the injector is configured for insertion into a patient's eye to inject ophthalmic tissue. Injector carriers include a container, a cap configured to seal an opening of the container. The injector can be coupled to a pressure actuated valve and a syringe where activating the syringe opens the value and allows fluid to flow from the syringe, through the valve, and through the injector to dispense ophthalmic tissue from the injector into a patient's eye without the need to physically contact the ophthalmic tissue.

A device that facilitates preparation of corneal grafts, including an illuminated base; and a corneal graft holder that can be selectively coupled to the illuminated base to illuminate a portion of donor cornea to facilitate preparation of the corneal graft.

A packaging system includes a packaging container and a packaging element. The packaging container include a first half having a base surface and an outer wall defining an inset receiving area, a second half sized and configured to couple to the first half in a locking relationship, and a coupling element extending from the base surface of the first half. The packaging element includes a central coupling body defining an opening sized and configured to receive the coupling element of the packaging container therethrough and a plurality of secondary coupling elements each coupled to an outer perimeter of the central coupling body. A plurality of surgical elements are each coupled to one of the plurality of secondary coupling elements.