The invention relates to biologically functional scaffolds having a porous structure, methods of preparing, and methods of use thereof. The invention also relates to methods of repairing a defect, methods of culturing cells and promoting differentiation of stem cells using the same.

The invention relates to biologically functional scaffolds having a porous structure, methods of preparing, and methods of use thereof. The invention also relates to methods of repairing a defect, methods of culturing cells and promoting differentiation of stem cells using the same.

An implantable lymph node replacement construct (10) comprising a body (12) having a plurality of inlets (24,26) and a lesser number of outlets (30). The body (12) further having an internal structure defining a fluid communication path through the body (12) from the inlets (24,26) to the outlet or outlets (30). The internal structure of the body (12) comprises an inlet portion (38), a convergent portion (40) and an outlet portion (42) such that lymph received by the construct (10) at the inlets (24,26) is conveyed through the inlet portion (38) of the internal structure to the convergent portion (40) whereupon the lymph is combined before passing to the outlet or outlets (30).

A nerve scaffold, including a membrane material and a degradable metal wire. The degradable metal wire is enclosed in the membrane material. The membrane material is biodegradable material, and includes three-dimensional pore structure. The degradable metal wire is horizontally and vertically distributed in the nerve scaffold.

A nerve scaffold, including a membrane material and a degradable metal wire. The degradable metal wire is enclosed in the membrane material. The membrane material is biodegradable material, and includes three-dimensional pore structure. The degradable metal wire is horizontally and vertically distributed in the nerve scaffold.

Dural repair devices that are configured to effectively and reliably repair the damage of a dural tear due to incidental durotomies are provided, along with methods of use. The devices and methods enhance the ability of a surgeon to repair a patients dura mater, or dura, during surgery of the central nervous system. The dural repair device has a multi-layer structure configured to exert a pressure or tamponade effect to compress a patient's dura to its state prior to the spinal surgery. Thus, the dural repair devices and methods of use may reduce the patients risk morbidity, further surgery, spinal headaches, or other injuries and discomforts.

There is disclosed an apparatus, a system and a method for treating asexual dysfunctional female patient. The apparatus comprises at least one expandable prosthesis adapted for implantation in female erectile tissue and adapted to be adjusted to temporarily achieve enlarged status of the female erectile tissue.

There is disclosed an apparatus, a system and a method for treating asexual dysfunctional female patient. The apparatus comprises at least one expandable prosthesis adapted for implantation in female erectile tissue and adapted to be adjusted to temporarily achieve enlarged status of the female erectile tissue.

An organ for transplantation having a kidney, a ureter, and a urinary bladder and an organ structure in which a first ureter, a first urinary bladder, a second ureter and a second urinary bladder are sequentially connected to a kidney can produce urine and excrete the produced urine, and thus is useful for transplantation.

An organ for transplantation having a kidney, a ureter, and a urinary bladder and an organ structure in which a first ureter, a first urinary bladder, a second ureter and a second urinary bladder are sequentially connected to a kidney can produce urine and excrete the produced urine, and thus is useful for transplantation.