An apparatus and method for the distillation of ocean and brackish water that includes a means for using the ambient temperatures of seawater and air to continually transfer the heat energy, from the outer perimeters of the system, back into the, centrally located, evaporation chamber and insulation for preventing heat from escaping to the atmosphere. The insulation comprises a first and second wall surrounding the basic assemblies of a desalination system in which the space between the first and second wall is under low partial vacuum and is partially filled with an insulation material for structural support. The system provides a feed through means that prevent heat transfer through the structural connections between the first and second walls. The system provides an evaporation system for flash evaporation by atomizing the input contaminated water, preheated by the heat of condensation into very small liquid droplets, which are then sprayed into a stream of hot dry air. The liquid rapidly evaporates leaving behind hot dry solids that is recaptured and used to preheat the input contaminated water.

A spray drier system is provided for spray drying a liquid sample such as blood plasma. The spray drier system may include a spray drier device adapted to couple with a spray drier assembly. The assembly may include an enclosure mounted to a frame. The assembly may receive a flow of drying gas which is directed by the enclosure shape towards a spray drying head mounted within the enclosure to the frame. Flows of a liquid sample may be further received by the head, which aerosolizes the liquid sample. Aerosolized liquid sample and drying air may be mixed within a drying chamber of the enclosure to produce dried sample and humid air. The dried sample and humid air may also be separated in a collection chamber of the enclosure, with the humid air exhausted from the enclosure.

A spray drier system is provided for spray drying a liquid sample such as blood plasma. The spray drier system may include a spray drier device adapted to couple with a spray drier assembly. The assembly may include an enclosure mounted to a frame. The assembly may receive a flow of drying gas which is directed by the enclosure shape towards a spray drying head mounted within the enclosure to the frame. Flows of a liquid sample may be further received by the head, which aerosolizes the liquid sample. Aerosolized liquid sample and drying air may be mixed within a drying chamber of the enclosure to produce dried sample and humid air. The dried sample and humid air may also be separated in a collection chamber of the enclosure, with the humid air exhausted from the enclosure.

A technology for protecting a valve seat inside a collection tank from the adherence of frozen particles in a vacuum freeze-drying apparatus and a frozen particle manufacturing method. The inside of a vacuum tank and a collection tank are vacuum evacuated; a raw material liquid is injected into the vacuum tank to produce frozen particles; and the frozen particles are piled up on a surface of a heating/cooling shelf. When the frozen particles on the heating/cooling shelf are transferred into the collection tank through the inside of an auxiliary pipe, the frozen particles do not adhere to a valve seat which surrounds an opening of a main pipe inside the collection tank.

A technology for protecting a valve seat inside a collection tank from the adherence of frozen particles in a vacuum freeze-drying apparatus and a frozen particle manufacturing method. The inside of a vacuum tank and a collection tank are vacuum evacuated; a raw material liquid is injected into the vacuum tank to produce frozen particles; and the frozen particles are piled up on a surface of a heating/cooling shelf. When the frozen particles on the heating/cooling shelf are transferred into the collection tank through the inside of an auxiliary pipe, the frozen particles do not adhere to a valve seat which surrounds an opening of a main pipe inside the collection tank.

The present system is for simultaneous recovery of purified water and dissolved solids from impure high TDS water (1) which is achieved in a single step and eliminates the use of external thermal energy for making the system significantly efficient. It eliminates the use of boiler, cooling tower that reduces the overall capital cost and continuous requirement of external thermal energy for making system efficient. The simultaneous recovery of the purified water and solids from high TDS input effluent reduce the energy intensity of the system. Said system provides a vacuum system as heat pump which enables the system to be self-sufficient in thermal energy requirements for evaporation process and reduces GHG emissions significantly.

Disclosed herein are DKP microcrystals made by an improved method where they do not irreversibly self-assemble into microparticles. The microcrystals can be dispersed by atomization and re-formed by spray drying into particles having spherical shell morphology. Active agents and excipients can be incorporated into the particles by spray drying a solution containing the components to be incorporated into microcrystalline diketopiperazine particles. In particular, the microcrystalline particle compositions are suitable for pulmonary drug delivery of one or more peptides, proteins, nucleic acids and/or small organic molecules.

Disclosed herein are DKP microcrystals made by an improved method where they do not irreversibly self-assemble into microparticles. The microcrystals can be dispersed by atomization and re-formed by spray drying into particles having spherical shell morphology. Active agents and excipients can be incorporated into the particles by spray drying a solution containing the components to be incorporated into microcrystalline diketopiperazine particles. In particular, the microcrystalline particle compositions are suitable for pulmonary drug delivery of one or more peptides, proteins, nucleic acids and/or small organic molecules.

Spray-dried encapsulated flavor powders are described, having particles that are large sized, highly flowable, fully dense, and highly dispersible and/or soluble, with low surface area to volume ratio, and high bulk density. Such flavor powders provide high retention of flavor components, and are advantageously produced by low temperature spray drying processes, e.g., single-step processes in which drying is intensified by techniques variously described herein.

A spray drying apparatus has a spray drying chamber; a liquid feed atomizer; a drying gas disperser; a perforated bottom; and a plenum chamber with an outlet below the perforated bottom. At least one guide plate is provided in the plenum chamber to direct gas, which is passing through the perforated bottom into the plenum chamber, towards the bottom of the plenum chamber. The guide plates have lower edges extending on average down to at least half-way between the perforated bottom of the spray drying chamber and the bottom of the plenum chamber.