Disclosed are methods for separating, recovering, and purifying cannabidiolic acid (CBDA) salts from an organic solvent solution comprising a mixture of cannabinoids. The methods comprise solubilizing the mixture of cannabinoids in C5-C7 hydrocarbon solvents, adding thereto a selected amine to thereby precipitate a CBDA-amine salt therefrom, dissolving the recovered CBDA-amine salt in a selected solvent and then adding thereto a selected antisolvent to thereby recrystallizing a purified CBDA-amine salt therefrom. The recrystallized CBDA-amine salt may be decarboxylated to form a mixture of cannabidiol (CBD) and amine. The CBD amine mixture may be acidified to separate the amine from CBD. The recovered CBD may be concentrated to produce a highly purified CBD. Also disclosed are CBDA-amine salts produced with certain amines selected from groups of secondary amines, tertiary amines, diamines, amino alcohols, amino ethers, and highly basic amines.

A method of making CBD concentrate or CBD Isolate comprises (a) milling a raw material; (b) contacting the milled raw material with an extraction solvent and separating a solid waste material to form a filtered extract; (c) concentrating the filtered extract; (d) washing the concentrated extract to form an organic phase and an aqueous phase; (e) separating the aqueous phase from the organic phase to form a washed extract; (f) removing an organic solvent from the washed extract to form a concentrated washed extract; (g) decarboxylating the concentrated washed extract; (h) vacuum distilling the decarboxylated extract to form a distillate; (i) dewaxing the distillate to form a post-dewax filtrate; (j) applying a vacuum to the post-dewax filtrate to form a post-dewax concentrate; (k) degassing the post-dewax concentrate; and (l) vacuum distilling the degassed concentrate to form a CBD concentrate.

The present invention relates to a novel process for crystallizing high purity lutein and zeaxanthin esters from marigold oleoresin. In another aspect, the present invention relates to the removal of soft and hard waxes by adsorption on diatomaceous earth or other filter aid using acetone or other organic solvent. Another aspect of the present invention relates to achieving high-purity lutein and zeaxanthin esters, including purity levels that are about 90 to 95%.

Embodiments may provide systems and method for purifying natural and/or organically certified nutraceuticals, such as cannabinoids. Embodiments may include refined or unrefined solvents, refined or unrefined plant extracts, refined or unrefined source compounds to be purified to any degree. Embodiments may reduce the concentration of impurities such as other cannabinoids (e.g., THC), terpenes, pesticides, herbicides, mycotoxins, heavy metals, other solvents (e.g., ethanol), waxes, or other impurities. Embodiments may increase the concentration of target compound(s) from its respective source material.

A process for the production of lithium carbonate from an aqueous salt solution at least containing lithium ions, chloride ions and calcium ions; the aqueous salt solution with a lithium content of at least 0.005% by weight and a maximum 0.2% by weight is condensed in a first evaporation step at a temperature between 40° C. and 160° C. until a concentrate I with a water content of ≤70% by weight and >60% by weight is formed. In a second evaporation step, the concentrate I is evaporated at a temperature between 60° C. and 180° C. until a concentrate II with a water content of ≤60% by weight is formed. In a Li concentration step, the lithium content is raised to at least 0.14% by heating the concentrate II to a temperature of at least 60° C. and thus a lithium-rich concentrate III and a residue III are formed.

A precipitation system for precipitating the target component is provided. The precipitation system includes: a reverse osmosis module; a precipitation device; a membrane separation device that includes a semipermeable membrane module including a first chamber and a second chamber separated by a semipermeable membrane, and that makes the feed solution after precipitation of the target component in the precipitation device flow to each of the first chamber and the second chamber and pressurizes the feed solution in the first chamber to transfer water into the second chamber via the semipermeable membrane and thereby concentrate the feed solution in the first chamber and dilute the feed solution in the second chamber; first return means for returning the feed solution concentrated in the membrane separation device to the precipitation device; and second return means for returning the feed solution diluted in the membrane separation device to the reverse osmosis module.

A system and method for crystallization and pelleting of a cannabinoid, including cannabidiol (CBD).

Disclosed are methods for separating, recovering, and purifying tetrahydrocannabinolic acid (THCA) salts from an organic solvent solution comprising a mixture of cannabinoids. The methods comprise solubilizing the mixture of cannabinoids in a selected C5-C7 hydrocarbon solvent, adding thereto a selected amine to thereby precipitate a THCA-amine salt therefrom, dissolving the recovered THCA-amine salt in a selected solvent and then adding thereto a selected antisolvent to thereby recrystallize a purified THCA-amine salt therefrom. The recrystallized THCA-amine salt may be decarboxylated to form a mixture of Δ9-tetrahydrocannabinol (Δ9-THC) and amine. The Δ9-THC amine mixture may be acidified to separate the amine from Δ9-THC. The recovered Δ9-THC may be concentrated to produce a highly purified Δ9-THC. Also disclosed are THCA-amine salts produced with amines selected from groups of diamines, amino alcohols, and tertiary amines.

The present disclosure relates to a method for extracting lithium from salt lake brine and simultaneously preparing aluminum hydroxide. This method includes: a. adding an aluminum salt to the brine to obtain a mixed salt solution A, adding an alkali solution to the mixed salt solution A for co-precipitation reaction, then subjecting to crystallization reaction and solid-liquid separation at the end of the reaction to obtain magnesium-aluminum hydrotalcite solid product and lithium-containing brine, wherein in step a, the alkali solution is an alkali solution free of carbonate ion; b. evaporating and concentrating the lithium-containing brine to obtain a lithium-rich brine, adding an aluminum salt to the lithium-rich brine to obtain a mixed salt solution B, adding an alkali solution dropwise to the mixed salt solution B to perform a co-precipitation reaction and solid-liquid separation after the end of the reaction to obtain a lithium-containing liquid and a lithium-containing layered material filter cake, wherein in step b, the alkali solution is an alkali solution free of carbonate ion; c. dispersing the lithium-containing layered material filter cake in deionized water to form a suspension slurry, then adjusting the pH value of the suspension slurry so as to carry out a lithium deintercalation reaction; d. filtering the slurry obtained after the lithium deintercalation reaction to obtain a lithium-containing solution and aluminum hydroxide filter cake; e. washing the aluminum hydroxide filter cake with deionized water and drying to obtain aluminum hydroxide solid.

A Reflux Rinsing apparatus for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. A pressure vessel contains a liquefied gas solvent, impure crystalline starting material initially, and a purified crystalline mass at the conclusion of the purifying process. A mechanism is provided for providing pressure to contents of the pressure vessel and for heating the lower portion thereof. A timer is also connected to the mechanism, the timer being set to heat the pressure vessel to drive vapors and reflux rinsing to remove impurities at the surface of an impure crystalline mass, to reclaim the solvent, leaving purified crystals and impurities in the pressure vessel, and to open the pressure vessel to remove the purified crystals from the vessel walls and bottom surface and to remove the impurities from the vessel. The angle of a crystal bed in the apparatus can be adjusted.