Single-stage and multi-stage systems and methods for the recovery of critical elements in substantially pure form from lithium ion batteries are provided. The systems and methods include supported membrane solvent extraction using an immobilized organic phase within the pores of permeable hollow fibers. The permeable hollow fibers are contacted by a feed solution on one side, and a strip solution on another side, to provide the simultaneous extraction and stripping of elements from dissolved lithium ion cathode materials, while rejecting other elements from the feed solution. The single- and multi-stage systems and methods can selectively recover cobalt, manganese, nickel, lithium, aluminum and other elements from spent battery cathodes and are not limited by equilibrium constraints as compared to traditional solvent extraction processes.

A system for and method of, processing post-consumer and post-industrial waste streams, producing active ingredients for waste stream processing, processing aqueous waste streams, preparing and collecting a multi-purpose chemical precursor, removing phosphates, nitrates, heavy metals, and other contaminants from aqueous waste streams, collecting and processing a post-consumer and post-industrial product from aqueous waste streams, administering and positioning assets and processes associated with waste stream processing, and scheduling operations for sub-systems of the system.

Disclosed herein are plinabulin polymorphs, compositions, their use and preparation as therapeutic agents. In particular, some embodiments relate to plinabulin monohydrate in a crystalline form.

The present invention primarily concerns a process for producing a plastic material, comprising the steps (i) providing a corn gluten source and a first liquid phase comprising an organic solvent; (ii) extracting solvent-soluble components of the corn gluten source into the first liquid phase; (iii) precipitating a first fraction of the solvent-soluble components out of the first liquid phase, resulting in a second solid phase including the first fraction of the solvent-soluble components and a second liquid phase including a second fraction of the solvent-soluble components; (iv) separating the second solid phase and the second liquid phase; and (v) recovering a flexible plastic material from the second liquid phase or recovering a hard plastic material from the second solid phase.

There is described a method of preparing solid particles of a compound, said method comprising controlling provision of a liquid phase, wherein said liquid phase comprises a solution of the compound, in a first flow direction to a membrane, said membrane defining a plurality of pores; and controlling the supersaturation of the liquid phase after it has passed through the membrane via the plurality of pores, to form solid particles of the compound. The method may comprise a continuous method.

The invention relates to a THC-free cannabinoid concentrate, method of obtaining the same and use thereof. The method of obtaining comprises an alkaline wash to purify lipid extracts.

Processes are described for obtaining highly purified tetrahydrocannabinolic acid (THCa) from Cannabis. Solvent extraction is performed on plant material or extract, followed by removal of impurities using sequential liquid-liquid extractions to purify cannabinoid carboxylic acids therefrom based on chemical properties of carboxylate salts. The product liquor, comprising THCa in solvent, is largely free of impurities, and high in THCa. Further steps can be conducted to obtain a highly enriched solution using chromatography and subsequent crystallization of THCa in 99% purity. THCa can be used as starting material for other products that include THC by decarboxylation. Optionally, triglyceride extraction of a washed aqueous phase can be used to prepare a THCa composition without chromatographic purification. A pre-processing aqueous extraction with pH manipulations may be used to remove biomass prior to solvent extraction, while maintaining THCa and optionally other cannabinoid acids.

Methods and systems for forming crystallized products from solutions. Such a method includes depositing an input material in a solvent mixture comprising a solvent and an anti-solvent, increasing the temperature of the solvent mixture with the input material therein to an elevated temperature for a period of time sufficient to fully dissolve the input material in the solvent mixture to form a solution of the material, and performing a series of temperature cycles on the solution to produce a crystallized product from the material in the solution. The solution is alternated between heating cycles and cooling cycles based on the turbidity of the solution, and the solution is filtered to remove and collect the crystallized product therefrom.

Described is a method of selectively isolating non-rigid structure meroterpenes (for example, cannabidiolic acid) from a complex matrix that may also contain rigid structure meroterpenes (for example, THCa), comprising selectively precipitating the non-rigid structure meroterpenes in the form of a triethylamine salt complex by adding triethylamine; isolating the triethylamine salt complex from the mother liquor; then heating the triethylamine salt complex to vaporize the triethylamine, leaving an isolated neutral non-rigid structure meroterpene. In certain embodiments, the starting product is a cannabis resin that has been solubilized in, for example, d-limonene.

The present application provides a process and system for extraction of rare earth elements using a long-term acid soak. In particular the present application provides a process for extracting rare earth elements from an ore by: (a) soaking the ore with a strong acid at a temperature of less than about 100° C. for at least 1 day; and (b) leaching the acid-soaked ore with an aqueous leaching solution to obtain a leachate comprising the rare earth elements. Optionally, a small amount of water is added to the acid during the acid soaking step and/or an additive comprising one or more metal ions is added to the acid during the acid soaking step.