A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.

A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.

A finger brace may provide flexion and/or lateral support for an injured finger. The finger brace may restrict motion of an injured finger and simultaneously provide a cold compress to an injured finger. The cold compress may be selectively attachable to the finger brace and provide localized treatment to the injured finger. A strap may secure the device onto one or more fingers of a user. The finger brace provides multi-modal treatment to an injured finger.

A wearable icepack holding apparatus is disclosed. The wearable icepack holding apparatus comprises a body and one or more fastening means. The body is configured to be worn on a user's head. The body comprises a first pocket at a first portion of the body. Further, the body comprises a plurality of second pockets at one or more second portions of the body. Each of the first pocket and the plurality of second pockets is configured to hold one or more icepacks. Further, the one or more fastening means are attached at a third portion of the body and are configured to adjust a grip of the body on the user's head.

A wearable icepack holding apparatus is disclosed. The wearable icepack holding apparatus comprises a body and one or more fastening means. The body is configured to be worn on a user's head. The body comprises a first pocket at a first portion of the body. Further, the body comprises a plurality of second pockets at one or more second portions of the body. Each of the first pocket and the plurality of second pockets is configured to hold one or more icepacks. Further, the one or more fastening means are attached at a third portion of the body and are configured to adjust a grip of the body on the user's head.

A cervical collar that facilitates therapeutic hypothermia is provided and includes a cooling device having a front portion and a back portion fixedly coupled to the front portion on one side and removably coupled to the front portion on an opposite side. A fastening device removably couples the back portion to the front portion on the opposite side. The cooling device induces hypothermia in at least a portion of a patient. A sensor is provided that measures a physical characteristic of the patient.

A cervical collar that facilitates therapeutic hypothermia is provided and includes a cooling device having a front portion and a back portion fixedly coupled to the front portion on one side and removably coupled to the front portion on an opposite side. A fastening device removably couples the back portion to the front portion on the opposite side. The cooling device induces hypothermia in at least a portion of a patient. A sensor is provided that measures a physical characteristic of the patient.

Isolated or recombinant anti-HER3 monoclonal antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer.

Isolated or recombinant anti-HER3 monoclonal antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer.

A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.