An endorectal cooling device (ECD) includes an elongated body, a cooling fluid circuit, and a gas bubble removal device. The elongated body includes an insertable portion for insertion into a patient's rectum and an external portion that remains external to the rectum. The cooling fluid circuit is defined in the elongated body from the external portion to the insertable portion and circulates cooling fluid to regulate a temperature of a cooling surface on the insertable portion. The gas bubble removal device can include a coil, a tube, a mesh, and/or a hole that is disposed on or defined in the insertable portion of the elongated body, such as the cooling surface. A low-pressure source, such as a vacuum pump or a Venturi structure, can be fluidly coupled to the gas bubble removal device to remove fluid and bubbles by a suction force after the ECD is inserted into the rectum.

An endorectal cooling device (ECD) includes an elongated body, a cooling fluid circuit, and a gas bubble removal device. The elongated body includes an insertable portion for insertion into a patient's rectum and an external portion that remains external to the rectum. The cooling fluid circuit is defined in the elongated body from the external portion to the insertable portion and circulates cooling fluid to regulate a temperature of a cooling surface on the insertable portion. The gas bubble removal device can include a coil, a tube, a mesh, and/or a hole that is disposed on or defined in the insertable portion of the elongated body, such as the cooling surface. A low-pressure source, such as a vacuum pump or a Venturi structure, can be fluidly coupled to the gas bubble removal device to remove fluid and bubbles by a suction force after the ECD is inserted into the rectum.

Methods, devices, and systems for temperature management of a patient having a viral infection or suffering from sepsis are disclosed. Methods, devices, and systems for raising a regional temperature of the patient to and/or actively maintaining a regional temperature of the patient at a target temperature are disclosed. The use of esophageal heat transfer devices to treat patients having a viral infection or suffering from sepsis is disclosed.

Methods, devices, and systems for temperature management of a patient having a viral infection or suffering from sepsis are disclosed. Methods, devices, and systems for raising a regional temperature of the patient to and/or actively maintaining a regional temperature of the patient at a target temperature are disclosed. The use of esophageal heat transfer devices to treat patients having a viral infection or suffering from sepsis is disclosed.

Provided is a magnetic nanoparticle heating method using resonance, the method including (a) providing magnetic nanoparticles, (b) applying a direct current (DC) magnetic field to the magnetic nanoparticles, and (c) applying an alternating current (AC) magnetic field to the magnetic nanoparticles 100, wherein a temperature change rate dT/dt of the magnetic nanoparticles is increased to at least 10 K/s or more by adjusting at least one of a strength of the DC magnetic field, a frequency of the AC magnetic field, a strength of the AC magnetic field, and a pulse width of the AC magnetic field.

Provided is a magnetic nanoparticle heating method using resonance, the method including (a) providing magnetic nanoparticles, (b) applying a direct current (DC) magnetic field to the magnetic nanoparticles, and (c) applying an alternating current (AC) magnetic field to the magnetic nanoparticles 100, wherein a temperature change rate dT/dt of the magnetic nanoparticles is increased to at least 10 K/s or more by adjusting at least one of a strength of the DC magnetic field, a frequency of the AC magnetic field, a strength of the AC magnetic field, and a pulse width of the AC magnetic field.

Methods, devices, and systems employ cryolysis of oropharyngeal adipose tissues to selectively remove fat cells from the tissues causing obstructive sleep apnea. In various embodiments, a chilled liquid—e.g., a liquid or air—is applied to the target tissue at a temperature and for a duration sufficient to cause cryolysis.

Methods, devices, and systems employ cryolysis of oropharyngeal adipose tissues to selectively remove fat cells from the tissues causing obstructive sleep apnea. In various embodiments, a chilled liquid—e.g., a liquid or air—is applied to the target tissue at a temperature and for a duration sufficient to cause cryolysis.

The present disclosure relates to a vaginal treatment device using LEDs, high-frequency waves, and EMS, the vaginal treatment device including: a main body part configured to be inserted into a vagina and having one or more LED irradiation units configured to irradiate an interior of the vagina with light, and electrode units configured to transfer radio frequency (RF) energy or electro muscular stimulation (EMS) energy into the vagina; a handle part embedded with a battery and having a power source member connected to one end of the main body part and configured to control transmission and reception to/from the LED irradiation units or the electrode units; and a housing part electrically connected to the handle part and configured to charge the battery.

A device comprising a heat-generating component that comprises an alkali metal is provided. The alkali metal in the presence of water at a point of contact of the device undergoes an exothermic reaction to generate heat in situ. The amount of heat generated is proportional to and/or limited by the amount (or moles) of water at the point of contact, and the heat generated is sufficient to achieve an increase in temperature at the point of contact to achieve a therapeutic or beneficial result. In one embodiment, the device is used for reducing sweat production in a subject suffering from excessive sweating or hyperhidrosis. In other embodiments, the device is used to substantially sterilize a surface or render a surface substantially aseptic.