The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid.

The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid.

A device and a method for cooling living tissues for a medical purpose and other purposes are proposed. The device may include a container configured to accommodate a cooling medium, the container including a plurality of divided members each having a contact surface which is thermally coupled with the cooling medium. The device may also include a cooling generator configured to provide cooling energy to the container, and disposed on another surface of the divided member other than the contact surface. The device may further include a lubricating member provided to the contact surface of the divided member, wherein the container is configured to be thermally coupled with the cooling medium via the lubricating member.

A device and a method for cooling living tissues for a medical purpose and other purposes are proposed. The device may include a container configured to accommodate a cooling medium, the container including a plurality of divided members each having a contact surface which is thermally coupled with the cooling medium. The device may also include a cooling generator configured to provide cooling energy to the container, and disposed on another surface of the divided member other than the contact surface. The device may further include a lubricating member provided to the contact surface of the divided member, wherein the container is configured to be thermally coupled with the cooling medium via the lubricating member.

A catheter is disclosed comprising a catheter shaft including a proximal end and a distal end. A flexible framework can be connected to the distal end of the catheter shaft, wherein the flexible framework includes a plurality of heating electrodes and a temperature sensor. The plurality of heating electrodes can be configured to be heated to a first temperature, the first temperature being lower than which radio frequency ablation is performed. The plurality of heating electrodes can be configured to be heated to a second temperature, the second temperature being a temperature at which radio frequency ablation is performed.

A catheter is disclosed comprising a catheter shaft including a proximal end and a distal end. A flexible framework can be connected to the distal end of the catheter shaft, wherein the flexible framework includes a plurality of heating electrodes and a temperature sensor. The plurality of heating electrodes can be configured to be heated to a first temperature, the first temperature being lower than which radio frequency ablation is performed. The plurality of heating electrodes can be configured to be heated to a second temperature, the second temperature being a temperature at which radio frequency ablation is performed.

A system includes an intravascular medical device and a therapeutic medical device. The intravascular medical device includes a heat therapy assembly and an elongated member coupled to the heat therapy assembly. The heat therapy assembly is configured to expand a vessel beyond an initial size of the vessel and deliver energy to a wall of the expanded vessel to heat the wall of the vessel. The therapeutic medical device is communicatively coupled to the heat therapy assembly and configured to control the heat therapy assembly to deliver the energy to ablate smooth muscle cells of the wall of the vessel and substantially denature one or more structural proteins of the wall of the vessel.

In examples, a cold therapy system includes an intravascular medical device and a therapeutic medical device. The intravascular medical device includes a cold therapy assembly and an elongated member. The cold therapy assembly includes one or more surfaces configured to remove heat from the wall of the vessel. The elongated member is coupled to the cold therapy assembly. The therapeutic medical device is communicatively coupled to the cold therapy assembly and is configured to control the cold therapy assembly to ablate smooth muscle cells of the wall of the vessel without substantially denaturating one or more structural proteins of the wall of the vessel.

The present disclosure relates to vision preservation systems for medical devices, such as cryospray devices for use with endoscopes. Exemplary embodiments provide a distal attachment in the form of a shroud or cap that mounts to the end of a flexible endoscope. A purging fluid supply mechanism is provided along the length of the endoscope, providing a channel for purging fluid, such as gas, to communicate between the endoscope tip and an external gas supply. The cap or shroud assembly incorporates a lens clearing flow field adjustment mechanism, such as nozzles, designed to direct warm (room temperature or higher) purging fluid across a lens at the scope tip. Another flow deflection mechanism, such as a guide or nozzle, may be included with the cap to direct purging fluid at an angle away from the lens. Gas, as an example, directed across and toward the lens purges moisture to avoid condensation on the lens and shears debris and bodily fluids away from the field of view. Gas directed or deflected by a guide away from the lens serves the purpose of keeping incoming particles and fluid droplets (e.g. spatter) from impacting on the lens cover. The cap and shroud are designed to avoid entraining moist air from the body cavity or lumen being treated.

The present disclosure relates to vision preservation systems for medical devices, such as cryospray devices for use with endoscopes. Exemplary embodiments provide a distal attachment in the form of a shroud or cap that mounts to the end of a flexible endoscope. A purging fluid supply mechanism is provided along the length of the endoscope, providing a channel for purging fluid, such as gas, to communicate between the endoscope tip and an external gas supply. The cap or shroud assembly incorporates a lens clearing flow field adjustment mechanism, such as nozzles, designed to direct warm (room temperature or higher) purging fluid across a lens at the scope tip. Another flow deflection mechanism, such as a guide or nozzle, may be included with the cap to direct purging fluid at an angle away from the lens. Gas, as an example, directed across and toward the lens purges moisture to avoid condensation on the lens and shears debris and bodily fluids away from the field of view. Gas directed or deflected by a guide away from the lens serves the purpose of keeping incoming particles and fluid droplets (e.g. spatter) from impacting on the lens cover. The cap and shroud are designed to avoid entraining moist air from the body cavity or lumen being treated.