Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.

The present disclosure relates to the technical field of solid-liquid separation of grain fermentation, and provides a solid-liquid separation mechanism and solid-liquid separation method for grain fermentation. A filter screen cylinder mechanism is inserted and mounted at an upper end of a rotating seat. According to the present disclosure, the rotation of the filter screen cylinder mechanism and a rotating disc mechanism has a speed difference, to realize the rolling and solid-liquid separation of fermented grain on an inner wall of the filter screen cylinder mechanism by rolling cylinders; and the rolling and solid-liquid separation is performed on fermented grain on an inner wall of the filter screen plate by the rolling cylinders, and the liquid in the fermented grain on the inner wall of the filter screen plate is rolled out, achieving a more thorough solid-liquid separation.

Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.

A separation device includes a rotating sieve including a mesh, a wall portion that defines a space in which the sieve rotates, a cover member that covers a gap between an annular portion on an outer periphery of the sieve and the wall portion, and an upper frame outside the space in which the sieve rotates, the cover member has an outer portion along the upper frame, an inner portion along the annular portion, and a bent portion between the outer portion and the inner portion, and the bent portion causes the inner portion to follow a change in a relative position between the sieve and the upper frame.

Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.