An apparatus includes a laser source and a scanner. The laser source is configured to generate electromagnetic radiation. The scanner scans at least part of a limbal area of an eye with the electromagnetic radiation generated by the laser source, thereby directing the electromagnetic radiation through an entire thickness of the limbal area of the eye without any contact with the eye and irradiating one or more regions of a trabecular meshwork of the eye with the electromagnetic radiation.

An apparatus includes a laser source and a scanner. The laser source is configured to generate electromagnetic radiation. The scanner scans at least part of a limbal area of an eye with the electromagnetic radiation generated by the laser source, thereby directing the electromagnetic radiation through an entire thickness of the limbal area of the eye without any contact with the eye and irradiating one or more regions of a trabecular meshwork of the eye with the electromagnetic radiation.

Disclosed herein are drug delivery punctal implants and methods of using the implants for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The physical arrangement of drugs within the punctal plugs disclosed herein results, in several embodiments, in advantageous controlled delivery of one or more drugs to the eye of a patient.

A robotic surgery system includes: (1) a positioning stage and (2) at least one manipulator arm mounted to the positioning stage, wherein the manipulator arm includes a track and a tool carriage moveably mounted to the track, and the tool carriage includes a base and a pair of light emitting devices mounted to the base.

In some embodiments, a microsurgical instrument includes a trocar having a rigid, hollow shaft formed with a lumen extending from a proximal end to a distal end of the shaft. The distal end of the shaft may be shaped for tissue penetration. The instrument may further include a composite microcannula slidably engaged with the trocar in the lumen. The microcannula includes a light guide and a flexible hollow tube having an outer diameter less than an inner diameter of the lumen in the trocar. Other embodiments include placing the microcannula in the lumen of the trocar, illuminating the end of the trocar by illuminating the end of the microcannula, advancing the trocar from a selected entry point on an eye into a selected structure in the eye, and extending the illuminated end of the microcannula from the trocar into the selected structure.

A fluid management system for an ophthalmic surgical system includes an irrigation system and an aspiration system. The irrigation system carries fluid toward a handpiece and includes an irrigation pump or a plurality of pumps. The aspiration system carries fluid away from the handpiece and includes an aspiration pump or the plurality of pumps. The pumps include at least one magnetic pump configured to move the fluid. The magnetic pump includes a plug system and a magnetic field system. The plug system includes one or more plugs disposed within a housing, where each plug comprises a magnetic material. The magnetic field system generates a magnetic field to move one or more of the plugs in order to move the fluid in a pumping direction.

A method of corneal implantation with cross-linking is disclosed herein. In one or more embodiments, the method includes the steps of: (i) prior to implantation, treating an implant formed from donor corneal tissue or a tissue culture grown corneal stroma with a solution of sodium dodecyl sulfate (SDS), Triton X-100, benzalkonium chloride (BAK), Igepal, genipin, 100% glycerol, or alcohol for making the implant acellular, and for killing any bacteria, viruses, or parasites prior to implantation; (ii) implanting the implant into a recipient cornea; (iii) applying laser energy to the implant so as to modify the refractive power of the implant while being monitored using a Shack-Hartmann wavefront system so as to achieve a desired refractive power for the implant; and (iv) applying a cross-linking solution and irradiating the implant to cross-link the implant to prevent an immune response to the implant and/or rejection of the implant by a patient.

A method of treating a subject with dry-form age-related macular degeneration (AMD) is disclosed. The method comprises administering into the subretina of the subject a therapeutically effective amount of a pharmaceutical composition comprising human RPE cells, wherein at least 95% of the cells thereof co-express premelanosome protein (PMEL17) and cellular retinaldehyde binding protein (CRALBP), and wherein the trans-epithelial electrical resistance of the cells is greater than 100 ohms to the subject, thereby treating the subject.

The present invention relates to a treatment device comprising: - an ultrasound generation unit (3) comprising an ultrasound module (32) including at least a transducer (321), - a hand-held part (2) comprising a gripping body (21), and a head (23) mounted on the body, the hand-held part and the ultrasound generation unit being designed to be joined together by contactless coupling means such that, when the hand-held part and the ultrasound generation unit are joined, the rotational movement of the upstream base between first and second positions causes the rotational movement of the ultrasound module between the first and second positions.

The invention relates to an arrangement and a software-based application for modifying an internal eye pressure in vivo, having modulating means for modifying the internal eye pressure and sensor means for capturing the internal eye pressure in vivo, and enabling easily operated and quickly reacting changes to the internal eye pressure while avoiding the disadvantages of the prior art, proposing that the modulating means are implemented for modifying the internal eye pressure as a function of the internal eye pressure captured by the sensor means.