A filtration device efficiently sizes removal of unnecessary substances adhering to and deposited on a filter medium of a filter element during filtration and backwashing (cleaning) from target (non-filtered) substances. The filter element captures substances in a fluid on one surface of a filter medium. The captured substances are separated from the filter medium during backwashing. A brush moves relative to the one surface of the filter medium and assists in separating the captured substances and sifting during the relative movement. The backwashing starts when a differential pressure between both surfaces of the filter medium exceeds a predetermined value, or the like while performing the filtration, and returns to filtration after the differential pressure is eliminated or after a predetermined time elapses. The brush sifts the unnecessary substances from the captured substances and passes the removal to the other surface side during the filtration.

Aspects herein include monitoring devices for filtration systems. An embodiment of the monitoring device can include a first fluid conduit and a first pressure sensor, wherein the first pressure sensor is in fluid communication with the first fluid conduit. The monitoring device can also include a second fluid conduit and a second pressure sensor, wherein the second pressure sensor is in fluid communication with the second fluid conduit. The monitoring device can also include a control circuit in electronic communication with the first pressure sensor and the second pressure sensor. The monitoring device can also include a housing, wherein the first pressure sensor, the second pressure sensor and the control circuit are all disposed within the housing. Other embodiments are also included herein.

A control system and a control method for automated controlling of a crossflow filtration system, as well as a corresponding crossflow filtration system, are provided. The control system comprises a measurement value processing unit configured to receive a plurality of sensor signals from a plurality of sensors of the crossflow filtration system; and to determine a plurality of process parameters defining an operation state of the crossflow filtration system based on the plurality of sensor signals.

A device and method for determining a filter element is approaching an end of life obtains vacuum data corresponding to a vacuum at a filter element, and concludes the filter element is approaching an end of life based on the vacuum data as it relates to time in service. The end of life of the filter element may be based on detection of a knee in a vacuum curve derived from the vacuum data, high and low vacuum measurements over a specific time period deviating from one another by more than a prescribed amount, or high and low vacuum curves derived from the vacuum data trending apart from one another by more than a prescribed amount.

An apparatus and method for filtering molten metal, such as aluminum or an aluminum alloy includes at least one ceramic foam filter or any other type of filtration media such as porous tube or alumina balls disposed in a receptacle for the molten metal. A vibrator vibrates at least one of the filter, the receptacle or the metal and may be used to induce priming, filtering and/or drainage of the filter. The vibrator may be retrofitted to an existing filter system and may be adjustable in frequency and amplitude. The vibration may be continuous over a given period or produced in a single shock.

A filtration system includes a variable speed pump having a direct current motor in communication with a source of fluid to be filtered, and a filter assembly having in communication the variable speed pump and with the source of fluid, such that the source of fluid, the variable speed pump and the filter assembly define a kidney-loop filtration circuit in which the fluid is circulated and filtered. A control circuit in communication with the direct current motor varies a voltage supplied to the direct current motor such that the speed of the direct current motor is variable and consequently the flow of fluid through the variable speed pump and through the filter assembly is variable between 0.05 gpm and 0.45 gpm. The direct current motor draws current and produces an output of less than 0.10 hp.

A filtration unit (1) comprising a support (10) arranged to receive a plurality of filter cartridges (11,11), the support configured to allow a displacement of the cartridges between a working position (70), in which a first filter cartridge (11) is arranged with own inlet/outlet apertures (71,71) in communication with a fluid inlet and outlet line portions (7,8), respectively, and at least one standby position (75) configured for receiving a respective second filter cartridge (11), an exchange mechanism (12) configured for causing the displacement of the cartridges between the at least one standby position and the working position, a differential pressure sensor (80) configured for measuring a pressure drop through first filter cartridge arranged in the working position and for generating a differential pressure signal (286) responsive to the pressure drop, a control unit (90) configured for receiving the differential pressure signal (86) and for providing an actuation signal (287) of the exchange mechanism, a program means resident in the control unit (90) and configured for generating the actuation signal (287) when the differential pressure signal indicates a pressure drop value exceeding a predetermined lower threshold value. This way, it is possible to arrange a clean filter cartridge in the at least one standby position, ready to be displaced to the working position in replacement of first filter cartridge, and the at least one second clean filter cartridge is transferred to the working position upon exceeding the differential pressure threshold value, remarkably limiting filter maintenance time and costs in a complex fluid distribution network.

An apparatus and method for filtering molten metal (M), such as aluminum or an aluminum alloy includes at least one ceramic foam filter or any other type of filtration media such as porous tube or alumina balls disposed in a receptacle (12) for the molten metal (M). A vibrator vibrates at least one of the filter, the receptacle (12) or the metal and may be used to induce priming, filtering and/or drainage of the filter. The vibrator may be retrofitted to an existing filter system and may be adjustable in frequency and amplitude. The vibration may be continuous over a given period or produced in a single shock.

The disclosure relates to a fuel filter assembly, a filter element, and a method of draining water from a fuel filter assembly. The fuel filter assembly comprises a filter element with a water collecting space; the filter element being connected to a fuel pipe for feeding an upstream side of the filter element with fuel and for providing filtered fuel from a downstream side of the filter element to a combustion engine or parts thereof; a fuel pump arranged downstream from the filter element, wherein the fuel pump can be operated in a first mode for drawing fuel through the filter element and in a second, reverse mode for feeding fuel back to the filter element; a one-way fuel valve arranged upstream of the filter element allowing for flow towards the upstream side of the filter element; a pressure-actuated one-way drain valve in communication with the water collecting space.

A method for purifying exosomes from a cell culture medium comprising combining at least three (03) treating stages of a sample containing exosomes in the following specific order: (A) filtering the sample containing exosomes by tangential flow filtration (TFF) to obtain a TFF-filtered sample; (B) centrifuging the TFF-filtered sample by sucrose cushion centrifugation (SCC) to obtain a SCC-centrifuged sample; and (C) purifying the SCC-centrifuged sample by bind-elute size exclusion chromatography (BE-SEC) to obtain a purified exosomes. The present invention provides a comprehensive and efficient approach for purifying exosomes from a cell culture medium, facilitating using exosomes in various biomedical applications.